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TECHNOLOGY & ENGINEERING --- Military Science --- Medicine, Military --- Drug interactions --- Drug utilization --- Pharmacological Processes --- Drug Information Services --- Occupational Groups --- Environmental Pollutants --- Product Surveillance, Postmarketing --- Biological Products --- Evaluation Studies as Topic --- Complex Mixtures --- Persons --- Pharmacological Phenomena --- Toxic Actions --- Information Services --- Pharmaceutical Services --- Physiological Processes --- Health Services --- Chemicals and Drugs --- Chemical Actions and Uses --- Investigative Techniques --- Physiological Phenomena --- Information Science --- Named Groups --- Phenomena and Processes --- Health Care Facilities, Manpower, and Services --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Health Care --- Adverse Drug Reaction Reporting Systems --- Drug Interactions --- Military Personnel --- Hazardous Substances --- Vaccines --- Medicine --- Health & Biological Sciences --- Military & Naval Medicine --- Evaluation --- Drug interactions. --- Evaluation. --- Interactions, Drug --- Drugs --- Side effects

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This book focuses of the neurotransmission phenomenon. By definition, neurotransmitters are chemicals that enable communication, i.e., the flow of nerve impulses between nerve cells or between nerve cells and muscles and glands. Recently, one can distinguish excitatory and inhibitory mediators, both of which are endo–exogenous compounds that control the function of the whole organism. From a chemical point of view, neurotransmitters belong to many different structural groups, such as amino acids (such as glycine), peptides (such as substance P, somatostatin), monoamines (such as noradrenaline or dopamine), purine derivatives (such as adenosine), gases (such as nitrogen, NO, carbon monoxide CO), and acetylcholine. From a medical point of view, disturbances in the concentration of neurotransmitters in the body result in the occurrence of mental disorders and diseases (such as depression, schizophrenia, Parkinson’s disease) and contribute to the occurrence of dementia (including Alzheimer’s disease), among other diseases. However, the problem is much wider. These disorders can lead to a number of cardiovascular diseases and can lead to the development of vascular diseases of the brain as well as in many other organs. Therefore, pharmacological intervention is a therapy that tries to interfere with regulatory processes year after year. Such treatments improve survival, reduce the frequency of readmission, and improve patients' quality of life.

white matter hyperintensities --- dysautonomia --- genetic polymorphisms --- dementia --- levodopa --- renin-angiotensin system --- orthostatic hypotension --- reserpine-induced fibromyalgia model --- vortioxetine --- ropinirole --- serotonin and dopamine in fibromyalgia --- mouse --- dopamine --- acetylcholine --- glutamate --- BDNF --- serotonin --- neurotransmitters --- statins --- neurodegenerative diseases --- stroke --- depression --- androgenetic alopecia --- 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors --- mixed dyslipidemia --- risk factors --- halogenated pyrazolines --- monoamine oxidase inhibitors --- kinetics --- reversibility --- molecular dynamics --- guanylate cyclase (GC) --- chronic heart failure (CHF) --- pulmonary arterial hypertension (PAH) --- tiagabine --- cardiac voltage-gated ion channels --- molecular modeling --- ECG study --- SGLT2i --- sodium-glucose cotransporter 2 inhibitors --- neuroprotection --- atheroprotection --- mTOR --- type 2 diabetes mellitus --- cognitive impairment --- inflammation --- oxidative stress --- antibiotics --- neurotoxicity --- adverse drug reaction --- neurotransmission --- 5-HT receptors --- gastrointestinal tract

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Pharmacology. Therapy --- Pharmacology --- Environmental toxicology --- Environmental Pollutants --- Pharmaceutical Preparations --- Pharmacologie --- Ecotoxicologie --- Periodicals --- periodicals --- toxicity --- Périodiques --- Drug Toxicity. --- Environmental Pollutants. --- Pharmacology. --- Écotoxicologie --- Périodiques. --- Toxicology. --- Evidence Based Toxicology --- Evidence-Based Toxicology --- Toxinology --- Based Toxicologies, Evidence --- Based Toxicology, Evidence --- Evidence Based Toxicologies --- Evidence-Based Toxicologies --- Toxicologies, Evidence Based --- Toxicologies, Evidence-Based --- Toxicology, Evidence Based --- Toxicology, Evidence-Based --- Pharmacogenetics --- Pharmacologies --- pharmacology --- Agriculture Sciences --- Health Sciences --- Veterinary Science --- Public health --- farmacologie --- toxicologie --- Toxicology --- Pollutants --- Pollutants, Environmental --- Environmental Pollutant --- Pollutant --- Pollutant, Environmental --- Radiation Exposure --- Environmental Exposure --- Environmental Pollution --- Adverse Drug Event --- Adverse Drug Reaction --- Drug Side Effects --- Drug Toxicity --- Side Effects of Drugs --- Toxicity, Drug --- Adverse Drug Events --- Adverse Drug Reactions --- Drug Event, Adverse --- Drug Events, Adverse --- Drug Reaction, Adverse --- Drug Reactions, Adverse --- Drug Related Side Effects and Adverse Reactions --- Drug Side Effect --- Drug Toxicities --- Effects, Drug Side --- Reactions, Adverse Drug --- Side Effect, Drug --- Side Effects, Drug --- Toxicities, Drug --- Drug Therapy --- Contraindications, Drug --- Drug Interactions --- Clinical Trials, Phase IV as Topic --- adverse effects

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Health Sciences --- Pharmacy and Pharmacology --- Therapeutics --- Internal medicine --- Internal medicine. --- Drug-Related Side Effects and Adverse Reactions. --- Drug Therapy. --- Medicine, Internal --- Medicine --- Therapy, Drug --- Chemotherapy --- Pharmacotherapy --- Chemotherapies --- Drug Therapies --- Pharmacotherapies --- Therapies, Drug --- Disease --- Pharmaceutical Preparations --- Pharmacologic Actions --- Adverse Drug Event --- Adverse Drug Reaction --- Drug Side Effects --- Drug Toxicity --- Side Effects of Drugs --- Toxicity, Drug --- Adverse Drug Events --- Adverse Drug Reactions --- Drug Event, Adverse --- Drug Events, Adverse --- Drug Reaction, Adverse --- Drug Reactions, Adverse --- Drug Related Side Effects and Adverse Reactions --- Drug Side Effect --- Drug Toxicities --- Effects, Drug Side --- Reactions, Adverse Drug --- Side Effect, Drug --- Side Effects, Drug --- Toxicities, Drug --- Drug Therapy --- Contraindications, Drug --- Drug Interactions --- Clinical Trials, Phase IV as Topic --- drug therapy --- therapeutic use --- adverse effects --- toxicity --- Internal Medicine

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Pharmacoepidemiology --- Chemotherapy --- Epidemiology --- Drug Therapy --- Drug Utilization --- Epidemiologic Methods --- Pharmacology, Clinical --- Pharmacoépidémiologie --- Médicaments --- adverse effects --- Effets secondaires --- Clinical Pharmacology --- Disease --- Epidemiologic Method --- Epidemiological Methods --- Methods, Epidemiologic --- Epidemiological Method --- Method, Epidemiologic --- Method, Epidemiological --- Methods, Epidemiological --- Utilization, Drug --- Drug Utilizations --- Utilizations, Drug --- Therapy, Drug --- Pharmacotherapy --- Chemotherapies --- Drug Therapies --- Pharmacotherapies --- Therapies, Drug --- Pharmaceutical Preparations --- Drugs --- epidemiology --- methods --- drug therapy --- therapeutic use --- Side effects --- Drug Utilization. --- Drug-Related Side Effects and Adverse Reactions. --- Epidemiologic Methods. --- Epidemiology. --- Pharmacology, Clinical. --- Product Surveillance, Postmarketing. --- Product Surveillance, Post-Marketing --- Drug Surveillance, Postmarketing --- Evaluation Studies, Postmarketing --- Postmarketing Product Surveillance --- Drug Surveillances, Postmarketing --- Evaluation Study, Postmarketing --- Post-Marketing Product Surveillance --- Post-Marketing Product Surveillances --- Postmarketing Drug Surveillance --- Postmarketing Drug Surveillances --- Postmarketing Evaluation Studies --- Postmarketing Evaluation Study --- Postmarketing Product Surveillances --- Product Surveillance, Post Marketing --- Product Surveillances, Post-Marketing --- Product Surveillances, Postmarketing --- Studies, Postmarketing Evaluation --- Study, Postmarketing Evaluation --- Surveillance, Post-Marketing Product --- Surveillance, Postmarketing Drug --- Surveillance, Postmarketing Product --- Surveillances, Post-Marketing Product --- Surveillances, Postmarketing Drug --- Surveillances, Postmarketing Product --- Adverse Drug Event --- Adverse Drug Reaction --- Drug Side Effects --- Drug Toxicity --- Side Effects of Drugs --- Toxicity, Drug --- Adverse Drug Events --- Adverse Drug Reactions --- Drug Event, Adverse --- Drug Events, Adverse --- Drug Reaction, Adverse --- Drug Reactions, Adverse --- Drug Related Side Effects and Adverse Reactions --- Drug Side Effect --- Drug Toxicities --- Effects, Drug Side --- Reactions, Adverse Drug --- Side Effect, Drug --- Side Effects, Drug --- Toxicities, Drug --- toxicity --- Contraindications, Drug --- Drug Interactions --- Clinical Trials, Phase IV as Topic --- Off-Label Use --- Social Epidemiology --- Epidemiologies, Social --- Epidemiology, Social --- Social Epidemiologies