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Book
Respiratory physiology of vertebrates : life with and without oxygen
Author:
ISBN: 9780521878548 0521878543 9780521703024 0521703026 9780511845178 9780511676703 0511676700 0511681194 9780511681196 0511845170 051173977X 1107210909 1282525867 9786612525865 0511677960 0511683170 0511679211 Year: 2010 Publisher: Cambridge : Cambridge University Press,

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Abstract

How do vertebrates get the oxygen they need, or even manage without it for shorter or longer periods of time? How do they sense oxygen, how do they take it up from water or air, and how do they transport it to their tissues? Respiratory system adaptations allow numerous vertebrates to thrive in extreme environments where oxygen availability is limited or where there is no oxygen at all. Written for students and researchers in comparative physiology, this authoritative summary of vertebrate respiratory physiology begins by exploring the fundamentals of oxygen sensing, uptake and transport in a textbook style. Subsequently, the reader is shown important examples of extreme respiratory performance, like diving and high altitude survival in mammals and birds, air breathing in fish, and those few vertebrates that can survive without any oxygen at all for several months, showing how evolution has solved the problem of life without oxygen.


Book
Management of high altitude pathophysiology
Authors: --- ---
ISBN: 0128140003 0128139994 9780128140000 9780128139998 Year: 2018 Publisher: London, England : Academic Press,


Book
Anoxia
Author:
ISBN: 9535151851 953307664X Year: 2012 Publisher: IntechOpen

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Abstract

This book reviews how severe oxygen deprivation affects biological systems - from the molecular to the ecological level. The contributing authors come from diverse regions of the world, which proves the interest in the academic analysis of oxygen deprivation. The diversity in the experimental approach scientists take, in order to understand the influence oxygen deprivation has on living systems, is apparent throughout this book. One of the presented ideas deals with the exploration and examination of the physiological, cellular and genetic characteristics of killifish embryos and nematodes exposed to anoxia. Furthermore, the book includes material on the mechanisms regulating hypoxia and anoxia tolerance and their implications of on human health issues. Finally, new methodologies to examine oxygen deprivation and the impact of human-related activities on oxygen level, within important ecological systems such as Lake Victoria, are presented. There is no doubt that the oxygen molecule is central to every stratum of biological systems.


Book
Hypoxia and Anoxia
Authors: --- ---
ISBN: 1789848296 1789848288 1838817514 Year: 2018 Publisher: IntechOpen

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Abstract

The molecular deprivation of oxygen is manifested by hypoxia, a deficiency of oxygen and anoxia, or the absence of oxygen supply to the tissues. This book entitled Hypoxia and Anoxia will cover a broad range of understanding on hypoxia and anoxia from molecular mechanisms to pathophysiology. Hypoxia and anoxia stimulate multiple systems through specific cell signal transduction pathways and regulate several transcriptional factors like HIF-1, REST to encode genes for VEGF, Epo, etc. This book will also highlight different types of hypoxia and anoxia along with their impact on apoptosis, cardiovascular pathophysiology, and glucose regulatory mechanisms. This book will be a ready reckoner to give a deep understanding of the oxygen-sensing environment in vivo for researchers, academicians, and clinicians throughout the world.


Book
Hypoxia
Author:
ISBN: 9781620817902 162081790X 1620817691 9781620817698 Year: 2013 Publisher: Hauppauge, N.Y.

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Abstract

Antioxidant and redox regulation of genes
Authors: --- ---
ISBN: 1281033626 9786611033620 0080527299 0126366705 9780126366709 9780080527291 9781281033628 Year: 2000 Publisher: San Diego Academic Press

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Abstract

This volume addresses oxidant-reduction or redox and antioxidant sensitive molecular mechanisms and how they are implicated in different disease processes. Possible strategies to pharmacologically and/or nutritionally manipulate such redox-sensitive molecular responses are emphasized.Key Features:* Reactive species as intracellular messengers* Redox regulation of cellular responses* Clinical implications of redox signaling and antioxidant therapy


Book
High altitude sickness - solutions from genomics, proteomics and antioxidant interventions
Authors: ---
ISBN: 9811910073 9811910081 Year: 2022 Publisher: Singapore : Springer,

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Abstract


Periodical
Hypoxia.
ISSN: 23241128 Year: 2013 Publisher: Auckland : Dove Medical Press,


Book
Hypoxia : Translation in Progress
Authors: --- ---
ISBN: 1489976760 1489976787 Year: 2016 Publisher: New York, NY : Springer US : Imprint: Springer,

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Abstract

The latest in a series of books from the International Hypoxia Symposia, this volume spans reviews on key topics in hypoxia, and abstracts from poster and oral presentations. The biannual International Hypoxia Symposia are dedicated to hosting the best basic scientific and clinical minds to focus on the integrative and translational biology of hypoxia. Long before ‘translational medicine’ was a catchphrase, the founders of the International Hypoxia Symposia brought together basic scientists, clinicians and physiologists to live, eat, ski, innovate and collaborate in the Canadian Rockies. This collection of reviews and abstracts is divided into six sections, each covering new and important work relevant to a broad range of researchers interested in how humans adjust to hypoxia, whether on the top of Mt. Everest or in the pulmonary or cardiology clinic at low altitude. The sections include: Epigenetic Variations in Hypoxia High Altitude Adaptation Hypoxia and Sleep Hypoxia and the Brain Molecular Oxygen Sensing Physiological Responses to Hypoxia Dr. Robert Roach is the Director of the Altitude Research Center at the University of Colorado. He specializes in the study of physiological adaptations by humans to high altitude, with a recent emphasis on the genomic responses to allow humans to thrive in hypoxia. Dr. Peter Wagner is a Distinguished Professor of Medicine and Bioengineering at the University of California, San Diego. His research addresses the theoretical and experimental basis of oxygen transport and its limitations in the lungs and skeletal muscles in health and disease. Dr. Peter Hackett is a world-renowned high altitude expert and altitude research pioneer. He is a leading authority on altitude illness, high altitude climbing, wilderness medicine, and the effects of altitude on people living and working in the mountains.


Book
Intermittent Hypoxia and Human Diseases
Authors: ---
ISBN: 1447129059 1447160223 1283911833 1447129067 Year: 2012 Publisher: London : Springer London : Imprint: Springer,

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Abstract

The scientific field of intermittent hypoxia and its effects on living organisms is surrounded by divergent and controversial findings. Does the condition play pathogenic roles in disease states, such as sleep apnea, chronic pulmonary disease, cardiovascular disease and cancer? Or does exposure to intermittent hypoxia actually induce protective responses? Dealing with these long-standing controversies and new concepts, Intermittent Hypoxia and Human Diseases provides an open forum for the most up-to-date scientific understanding of both adaptive (beneficial) and maladaptive (detrimental) responses to intermittent hypoxia and their potential pathogenic and prophylactic roles in the development and progression of major human diseases. The Editors and their extremely experienced contributors have assembled this highly disease-oriented book and all the fundamental research findings are selectively presented as mechanistic explanations of a particular human disease. It is therefore especially prepared for the interests of clinicians, allied healthcare professionals, athletic trainers, and translational medical researchers.

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