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This book presents an overview of the most important current developments in the pre-analytical handling of tissue. It addresses in particular potential ways to improve the situation whereby methods employed in the pre-analytical phase – the period from surgical removal of tissue to the start of pathological processing – have remained essentially unchanged for decades with only modest standardization. It is examined how the pre-analytical period can be optimized, resulting not only in an increase in diagnostic quality but also in a reduction in processing time and costs. Among the key topics examined are the so-called cold ischemia time between tissue removal and fixation, the potential superiority of vacuum-based preservation over immediate formalin fixation, two-temperature fixation, molecular analysis methods, and the pre-analytics of specimens from particular tissues. Readers will find this book to be an important update that reveals the full importance of the pre-analytical phase for quality of pathological work-up.

Medicine & Public Health. --- Oncology. --- Pathology. --- Surgery. --- Laboratory Medicine. --- Medicine. --- Medical laboratories. --- Médecine --- Cancérologie --- Pathologie --- Chirurgie --- Medicine --- Health & Biological Sciences --- Oncology --- Disease (Pathology) --- Laboratory medicine. --- Medical sciences --- Diseases --- Medicine, Preventive --- Tumors --- Surgery, Primitive --- Clinical medicine --- Clinical pathology --- Diagnostic laboratory tests --- Laboratory diagnosis --- Laboratory medicine --- Medical laboratory diagnosis --- Diagnosis --- Pathology --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Physicians --- Oncology  . --- Diagnosis, Laboratory --- Health facilities --- Laboratories --- Biology --- Biomedical Research. --- Research. --- Biological research --- Biomedical research --- Health Workforce