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The shattered self : the end of natural evolution
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ISBN: 0333674790 0262250683 1282099817 0262267632 9780585388490 9786612099816 0585388490 9780585388496 0262025027 9780262025027 661209981X 9780262267632 9780333674796 0312230117 9780312230111 0262523345 9780262523349 9780262250689 9781282099814 Year: 2001 Publisher: Cambridge ( Mass.): MIT Press,

DNA microarrays and gene expression
Authors: ---
ISBN: 1107130174 1280160411 9786610160419 0511063210 0511119224 1139146947 0511056885 0511322674 0511541775 0511071671 9780511063213 9780511071676 9780511541773 9780521800228 0521800226 9781280160417 9780521176354 0521176352 Year: 2002 Publisher: Cambridge, UK ; New York, NY : Cambridge University Press,

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Abstract

Massive data acquisition technologies, such as genome sequencing, high-throughput drug screening, and DNA arrays are in the process of revolutionizing biology and medicine. Using the mRNA of a given cell, at a given time, under a given set of conditions, DNA microarrays can provide a snapshot of the level of expression of all the genes in the cell. Such snapshots can be used to study fundamental biological phenomena such as development or evolution, to determine the function of new genes, to infer the role individual genes or groups of genes may play in diseases, and to monitor the effect of drugs and other compounds on gene expression. Originally published in 2002, this inter-disciplinary introduction to DNA arrays will be of value to anyone with an a interest in this powerful technology.

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