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"There are 7,000 rare diseases affecting 6%-8% of the global population. That's 3.5 million people in the UK alone. Yet only 200 rare diseases have approved treatments. In recent years, there has been a surge of interest from business and social entrepreneurs in the field of health - including looking at ways to treat rare disease patients better and faster. This book presents some of the latest developments in the world of rare disease entrepreneurship from a global group of experts. It examines the topic from the business angle, considering the drug development process and providing case studies of successful orphan drug enterprises. It also looks at rare diseases from the perspective of the patient, analysing the growing rare disease patient movement, a successful patient group that uses social enterprise techniques, and chapters on key requirements for helping patients with rare diseases through registries and centres of excellence. The book will be an essential toolkit for social and business entrepreneurs who are interested in the world of rare/orphan diseases. It has the rigour of an academic publication, along with the clarity of a lay publication. An original and timely book, Rare Diseases will help to add knowledge and awareness to a vastly under-published subject."--Provided by publisher.

Rare diseases --- Entrepreneurship --- Orphan Drug Production --- Drug therapy --- Organization & administration --- Methods --- Entrepreneur --- Intrapreneur --- Rare disorders --- Uncommon diseases --- Capitalism --- Business incubators --- Diseases --- Pharmaceutical industry --- Drug industry --- Drug trade --- Medicine industry --- Medicines industry --- Prescription medicine industry --- Chemical industry --- E-books

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Children and Drug Safety traces the development, use, and marketing of drugs for children in the twentieth century, a history that sits at the interface of the state, business, health care providers, parents, and children. This book illuminates the historical dimension of a clinical and policy issue with great contemporary significance-many of the drugs administered to children today have never been tested for safety and efficacy in the pediatric population. Each chapter of Children and Drug Safety engages with major turning points in pediatric drug development; themes of children's risk, rights, protection and the evolving context of childhood; child-rearing; and family life in ways freighted with nuances of race, class, and gender. Cynthia A. Connolly charts the numerous attempts by Congress, the Food and Drug Administration, the American Academy of Pediatrics, and leading pediatric pharmacologists, scientists, clinicians, and parents to address a situation that all found untenable.

Pediatric pharmacology --- Drugs --- Medical policy --- Drug Therapy --- Child --- Drug and Narcotic Control --- Health Policy --- History, 20th Century --- 20th Cent. History (Medicine) --- 20th Cent. History of Medicine --- 20th Cent. Medicine --- Historical Events, 20th Century --- History of Medicine, 20th Cent. --- History, Twentieth Century --- Medical History, 20th Cent. --- Medicine, 20th Cent. --- 20th Century History --- 20th Cent. Histories (Medicine) --- 20th Century Histories --- Cent. Histories, 20th (Medicine) --- Cent. History, 20th (Medicine) --- Century Histories, 20th --- Century Histories, Twentieth --- Century History, 20th --- Century History, Twentieth --- Histories, 20th Cent. (Medicine) --- Histories, 20th Century --- Histories, Twentieth Century --- History, 20th Cent. (Medicine) --- Twentieth Century Histories --- Twentieth Century History --- Children --- Minors --- Pharmacology --- History --- history --- standards --- Drug effects --- Effect of drugs on --- United States. --- E-books --- United States --- children medication. --- children. --- drug safety. --- drug. --- drugs children. --- medication. --- pharmaceutical. --- pharmacy. --- pills. --- therapy. --- History, 20th Century. --- Child. --- history. --- standards.

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Cacchioni moves beyond the search for a sexual pharmaceutical drug for women to ask a broader question: how does the medicalization of female sexuality already affect women's lives?

Pharmaceutical industry --- Women --- Sexual disorders --- Sex disorders --- Sexual diseases --- Sex (Biology) --- Psychosexual disorders --- Female sexuality --- Drug industry --- Drug trade --- Medicine industry --- Medicines industry --- Prescription medicine industry --- Chemical industry --- Social aspects. --- Sexual behavior. --- Drug use. --- Treatment. --- Sexual Dysfunctions, Psychological --- Drug Industry --- Sexual Behavior --- Sociological Factors --- Women's Health --- Woman's Health --- Womens Health --- Health, Woman's --- Health, Women's --- Health, Womens --- Social Attributes --- Social Characteristics --- Social Traits --- Sociological Characteristics --- Sociological Phenomena --- Attribute, Social --- Attributes, Social --- Characteristic, Sociological --- Characteristics, Social --- Characteristics, Sociological --- Factor, Sociological --- Factors, Sociological --- Phenomena, Sociological --- Social Attribute --- Social Trait --- Sociological Characteristic --- Sociological Factor --- Trait, Social --- Traits, Social --- Industries, Pharmaceutic --- Industry, Drug --- Industry, Pharmaceutic --- Industry, Pharmaceutical --- Pharmaceutical Industry --- Drug Industries --- Industries, Drug --- Industries, Pharmaceutical --- Pharmaceutic Industries --- Pharmaceutic Industry --- Pharmaceutical Industries --- Girls --- Woman --- Women's Groups --- Girl --- Women Groups --- Women's Group --- Social aspects --- Sexual behavior --- Drug use --- Treatment --- drug therapy --- drug effects --- E-books --- asexuality. --- big pharma. --- female sexual dysfunction. --- heteronormativity. --- medicalization. --- queering heterosex. --- sexual pain. --- sexual pharmaceuticals. --- Industrie pharmaceutique --- Femmes --- Troubles sexuels --- Aspect social --- Sexualité --- Usage des drogues --- Traitement

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The Agreement on Trade Related Aspects of Intellectual Property rights (TRIPS) requires all WTO members to adopt certain minimum standards for the protection of intellectual property rights including the rights of holders of patents for pharmaceutical products. The adoption of the standards delineated by the TRIPS Agreement appears to have resulted in significant loss of public health policy flexibilities for developing country members with respect to regulating the grant and use of pharmaceutical patents and controlling the cost of medicines. The Agreement, however, provides inherent flexibil

Antiretroviral agents. --- Antiretroviral agents --- Delivery of Health Care --- Anti-Retroviral Agents --- Africa --- Intellectual Property --- Industry --- Patient Care Management --- Geographic Locations --- Antiviral Agents --- Technology, Industry, and Agriculture --- Jurisprudence --- Health Care Quality, Access, and Evaluation --- Geographicals --- Social Control, Formal --- Health Services Administration --- Technology, Industry, Agriculture --- Health Care --- Anti-Infective Agents --- Therapeutic Uses --- Health Care Economics and Organizations --- Sociology --- Pharmacologic Actions --- Social Sciences --- Chemical Actions and Uses --- Anthropology, Education, Sociology and Social Phenomena --- Chemicals and Drugs --- Africa South of the Sahara --- Health Services Accessibility --- Drug Industry --- Anti-HIV Agents --- Patents as Topic --- Medicine --- Health & Biological Sciences --- Clinical Immunology --- Trademarks --- Patents as Topics --- Trademark --- Anti-AIDS Drugs --- Anti-HIV Drugs --- AIDS Drugs --- Anti-AIDS Agents --- Agents, Anti-AIDS --- Agents, Anti-HIV --- Anti AIDS Agents --- Anti AIDS Drugs --- Anti HIV Agents --- Anti HIV Drugs --- Drugs, AIDS --- Drugs, Anti-AIDS --- Drugs, Anti-HIV --- Industries, Pharmaceutic --- Industry, Drug --- Industry, Pharmaceutic --- Industry, Pharmaceutical --- Pharmaceutical Industry --- Drug Industries --- Industries, Drug --- Industries, Pharmaceutical --- Pharmaceutic Industries --- Pharmaceutic Industry --- Pharmaceutical Industries --- Accessibility, Health Services --- Contraceptive Availability --- Health Services Geographic Accessibility --- Program Accessibility --- Access to Health Care --- Accessibility of Health Services --- Availability of Health Services --- Accessibility, Program --- Availability, Contraceptive --- Health Services Availability --- Chemical Actions --- Actions, Chemical --- Actions, Pharmacologic --- General Social Development and Population --- Healthcare Economics and Organizations --- Therapeutic Effects --- Effects, Therapeutic --- Uses, Therapeutic --- Anti-Microbial Agents --- Antiinfective Agents --- Antimicrobial Agents --- Microbicides --- Agents, Anti-Infective --- Agents, Anti-Microbial --- Agents, Antiinfective --- Agents, Antimicrobial --- Anti Infective Agents --- Anti Microbial Agents --- Community-Based Distribution --- Contraceptive Distribution --- Delivery of Healthcare --- Dental Care Delivery --- Distribution, Non-Clinical --- Distribution, Nonclinical --- Distributional Activities --- Healthcare --- Healthcare Delivery --- Healthcare Systems --- Non-Clinical Distribution --- Nonclinical Distribution --- Delivery of Dental Care --- Health Care Delivery --- Health Care Systems --- Activities, Distributional --- Activity, Distributional --- Care, Health --- Community Based Distribution --- Community-Based Distributions --- Contraceptive Distributions --- Deliveries, Healthcare --- Delivery, Dental Care --- Delivery, Health Care --- Delivery, Healthcare --- Distribution, Community-Based --- Distribution, Contraceptive --- Distribution, Non Clinical --- Distributional Activity --- Distributions, Community-Based --- Distributions, Contraceptive --- Distributions, Non-Clinical --- Distributions, Nonclinical --- Health Care System --- Healthcare Deliveries --- Healthcare System --- Non Clinical Distribution --- Non-Clinical Distributions --- Nonclinical Distributions --- System, Health Care --- System, Healthcare --- Systems, Health Care --- Systems, Healthcare --- Science, Social --- Sciences, Social --- Social Science --- Administration, Health Services --- Health Services --- Regulation --- Social Control --- Control, Social --- Controls, Social --- Formal Social Control --- Formal Social Controls --- Regulations --- Social Controls --- Healthcare Quality, Access, and Evaluation --- Constitutional Law --- Court Decision --- Law --- Legal Aspects --- Legal Obligations --- Legal Status --- State Interest --- Litigation --- Medical Jurisprudence --- Aspect, Legal --- Aspects, Legal --- Constitutional Laws --- Court Decisions --- Decision, Court --- Decisions, Court --- Interest, State --- Interests, State --- Jurisprudence, Medical --- Law, Constitutional --- Laws --- Laws, Constitutional --- Legal Aspect --- Legal Obligation --- Litigations --- Obligation, Legal --- Obligations, Legal --- State Interests --- Status, Legal --- Antiviral Drugs --- Antivirals --- Agents, Antiviral --- Drugs, Antiviral --- Care Management, Patient --- Management, Patient Care --- Tertiary Sector --- Industries --- Sector, Tertiary --- Sectors, Tertiary --- Tertiary Sectors --- Intellectual Properties --- Properties, Intellectual --- Property, Intellectual --- Antiretroviral Agents --- Agents, Anti-Retroviral --- Agents, Antiretroviral --- Anti Retroviral Agents --- Anti-retroviral agents --- Antiretroviral drugs --- Antiretrovirals --- organization & administration --- Antiretroviral Therapy, Highly Active --- Medically Underserved Area --- Pharmacological and Toxicological Phenomena --- Drug Therapy --- Infection --- Parasites --- Public Policy --- Defamation --- Lawyers --- Interferon Inducers --- Virus Diseases --- Viruses --- Virus Inactivation --- Commerce --- Ethics, Business --- Ownership --- Inventions --- Antiviral agents --- Infections --- Access To Medicines --- Access to Contraception --- Access to Health Services --- Access to Medications --- Access to Therapy --- Access to Treatment --- Contraception Access --- Contraceptive Access --- Medication Access --- Access To Medicine --- Access to Contraceptions --- Access to Medication --- Access to Therapies --- Access to Treatments --- Access, Contraception --- Access, Contraceptive --- Access, Medication --- Contraception, Access to --- Contraceptive Accesses --- Medication Accesses --- Medication, Access to --- Therapy, Access to --- Treatment, Access to --- Health Care Economics --- Health Economics --- Healthcare Economics --- Care Economic, Health --- Economic, Health --- Economic, Health Care --- Economic, Healthcare --- Economics, Health Care --- Health Care Economic --- Health Economic --- Healthcare Economic --- Therapeutic Effect --- Therapeutic Use --- Effect, Therapeutic --- Use, Therapeutic --- Anti-Infective Agent --- Anti-Microbial Agent --- Antimicrobial Agent --- Microbicide --- Agent, Anti-Infective --- Agent, Anti-Microbial --- Agent, Antimicrobial --- Anti Infective Agent --- Anti Microbial Agent --- Antiviral --- Antiviral Agent --- Antiviral Drug --- Agent, Antiviral --- Drug, Antiviral --- Subsaharan Africa --- Africa, Sub-Saharan --- Sub-Saharan Africa --- Access To Care, Health --- Access to Care --- Access to Medicines --- Access to Cares --- Access to Medicine --- Care, Access to --- Cares, Access to --- Medicine, Access to --- Medicines, Access to --- Accessibilities, Health Services --- Agreement on Trade-Related Aspects of Intellectual Property Rights