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This book, based on published studies, takes a unique perspective on the 30-year collapse of pharmaceutical industry productivity in the search for small molecule "magic bullet" interventions. The relentless escalation of inflation-adjusted cost per approved medicine in the United States - from 200 million in 1950 to 1.2 billion in 2010 - has driven industry giants to, at best, slavish imitation in drug design, and at worst, abandonment of research and embracing of widespread fraud in consumer marketing.The book adapts formalism across a number of disciplines to the strategy for design of mu

Drug development. --- Drugs --- Medical geography. --- Diseases --- Geographical distribution of diseases --- Geographical pathology --- Geography, Medical --- Geomedicine --- Medical topography --- Pathology, Geographic --- Topography, Medical --- Geography --- Medical climatology --- World health --- Medicaments --- Medications --- Medicine (Drugs) --- Medicines (Drugs) --- Pharmaceuticals --- Prescription drugs --- Bioactive compounds --- Medical supplies --- Pharmacopoeias --- Chemotherapy --- Materia medica --- Pharmacology --- Pharmacy --- Pharmaceutical research --- Development of drugs --- New drug development --- Research. --- Design --- Mathematical models. --- Geographical distribution --- Research --- Development --- Pharmaceutical industry --- Drug industry --- Drug trade --- Medicine industry --- Medicines industry --- Prescription medicine industry --- Chemical industry --- Economic aspects --- Government policy --- E-books