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Ce Document d'orientation sur les indicateurs de performance en matière de sécurité propose une approche systémique pour évaluer le succès des programmes mis en place par les différents intervenants en matière de sécurité chimique. Il laisse par ailleurs aux groupes concernés une certaine latitude pour concevoir des programmes permettant d'évaluer leurs propres performances dans le contexte de la prévention, de la préparation et de l'intervention en matière d'accident chimique. Les indicateurs de performance en matière de sécurité (IPS) aident l'industrie, les autorités et les collectivités à déterminer dans quelle mesure leurs actions contribuent à améliorer la sécurité chimique.

Chemicals --- Safety measures

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This guidance document was originally published in 2012 and updated in 2018 to reflect new and updated OECD test guidelines, as well as reflect on scientific advances in the use of test methods and assessment of the endocrine activity of chemicals. The document is intended to provide guidance for evaluating chemical using standardised test guidelines. Specific objectives include providing a description of the OECD conceptual framework for evaluating chemicals for endocrine disruption, background on the standardised test methods used, and guidance for interpreting the outcome of individual tests. The general approach taken by the document is primarily to provide guidance on how test results might be interpreted based on the outcome of standardised assays. Key questions addressed in the document concern likely mechanisms of endocrine action and any resulting apical effects that can be attributed to such action. The document is not proscriptive but provides suggestions for possible next steps in testing (if any) which might be appropriate for a regulatory authority to take, given the various data scenarios. The guidance document is focused primarily on endocrine modalities included in the conceptual framework; estrogen, androgen, and thyroid mediated endocrine disruption and chemicals that interfer with steroidogenesis.

Endocrine disrupting chemicals.

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Petroleum chemicals industry --- Petroleum chemicals --- Petroleum industry and trade --- Prices

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This Guidance on Developing Safety Performance Indicators (“Guidance on SPI”) was prepared to assist enterprises that wish to implement and/or review Safety Performance Indicator Programmes. The three chapters in this Guidance are designed to help enterprises better understand safety performance indicators, and how to implement SPI Programmes. Specifically, Chapter 1 provides important background information on the Guidance and on SPIs more generally including (i) a description of the target audience for this Guidance, (ii) defi nitions of SPIs and related terms, and (iii) insights on the reasons for implementing an SPI Programme. Chapter 2 sets out a seven-step process for implementing an SPI Programme, along with three examples of how different types of enterprises might approach the establishment of such a Programme. These seven steps build on the experience of a number of enterprises in the UK that worked with the Health and Safety Executive to develop a practical approach for applying performance indicators. Chapter 3 provides additional support for the development of an SPI Programme by setting out a menu of possible elements (targets, outcome indicators and activities indicators). This menu is extensive in light of the different types of potentially interested enterprises, recognising that each enterprise will likely choose only a limited number of the elements to monitor its key areas of concern. Furthermore, it is understood that an enterprise may decide to implement an SPI Programme in steps, focusing fi rst on only a few priority areas, and then expanding and amending its Programme as experience is gained. Annexes provide further support with an expanded explanation of metrics and a summary of targets, along with a glossary, a list of selected references and a copy of the Guiding Principles’ “Golden Rules.”

Hazardous substances --- Chemicals --- Accidents --- Dangerous chemicals --- Dangerous goods --- Dangerous materials --- Dangerous substances --- Hazardous chemicals --- Hazardous goods --- Hazardous materials --- Hazmats --- Materials

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This Guidance Document is addressed to those who are involved in risk assessment and management of chemicals called POPs (persistent organic pollutants) or PBTs (persistent and bio-accumulating toxics). It is about using multimedia models, i.e. generic evaluative models that can calculate overall environmental persistence (Pov) and potential for long-range transport (LTRP) covering multiple compartments such as air, water, sediment and soil: what models you can use to identify and characterize POPs/PBTs, what data to use, and how to use model calculations.

Persistent pollutants --- Environmental aspects --- Persistent chemicals --- Pollutants