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This 2028 Special Issue presents recent developments and achievements in the field of Mechanism and Machine Science coming from the Italian community with international collaborations and ranging from theoretical contributions to experimental and practical applications. It contains selected contributions that were accepted for presentation at the Second International Conference of IFToMM Italy, IFIT2018, that has been held in Cassino on 29 and 30 November 2018. This IFIT conference is the second event of a series that was established in 2016 by IFToMM Italy in Vicenza. IFIT was established to bring together researchers, industry professionals and students, from the Italian and the international community in an intimate, collegial and stimulating environment.

biomechanical engineering --- wearable robotics --- hand exoskeleton --- mechanism design and optimization --- kinematic analysis --- mechatronics --- Handwheelchair.q --- Disabled sport --- Manual wheelchair --- water wheel --- grain water mill --- wooden teeth gear --- history of mechanism and machine science --- micro-hydro --- renewable energy --- magneto-rheological elastomers --- smart materials --- semi-active isolator --- iron powder --- wearable device --- blood ultrafiltration --- mechatronic device --- renal replacement --- bevel gears --- gear design --- Tredgold --- numerical simulations --- shape memory alloy --- SMA wires --- flexible actuator --- modular actuator --- mathematical model --- experimental test --- tilting pad journal bearing --- nonlinear behavior --- experimental characterization --- stiffness modelling --- performance indices --- condition number --- volumetric isotropy index --- parallel manipulator --- two-stage planetary gearbox --- varying load --- dynamic torque --- efficiency --- rotating machinery --- Intelligent tire --- flex sensor --- PVDF sensor --- energy saving --- vehicle dynamics --- smart systems --- vibroprotection --- seismic --- rolling bearer --- vibration --- non-linear vibrations --- cumulative curves --- singular point --- n/a