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The Human Genome Project has spawned a Renaissance of research faced with the daunting expectation of personalized medicine for individuals with sickle cell disease in the Genome Era. This book offers a comprehensive and timeless account of emerging concepts in clinical and basic science research, and community concerns of health disparity to educate professionals, students and the general public about meeting this challenging expectation. Contributions from physicians, research scientists, scientific administrators and community workers make Renaissance of Sickle Cell Disease Research in the

Sickle cell anemia. --- Genomics.

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Proudly open access, the Journal of Sickle Cell Disease (JSCD) is committed to upholding rigorous scientific standards while ensuring researchers, clinicians, patients, and the public have unobstructed access to the latest discoveries. We eagerly invite contributions from all corners of the globe, united in our ambition to enhance the lives of all those affected by sickle cell disease.

Sickle cell anemia --- Diseases --- Treatment.

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This text represents multidisciplinary and international efforts and a combination of research and service. Containing information for patients and families, this volume will be useful to those helping children and their families through the treatment, recovery and grieving process.

Cancer in children. --- Sickle cell anemia in children. --- Cancer in children --- Childhood cancer --- Pediatric cancer --- Tumors in children --- Anemia in children --- Psychological aspects. --- Sickle cell anemia in children

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This book addresses a wide range of clinically relevant topics and issues in sickle cell disease. This is written by experts in their own field offering a robust, engaging discussion about the presentations and mechanisms of actions in the multiple complications associated with sickle cell disease. This first of the series addresses pain, which is considered the hallmark of sickle cell presentation. It looks at the basic mechanism of pain in sickle cell disease. A more detailed review of precision medicine gives a clear well laid out presentation that is incisive and yet gives in-depth detail relevant to both the clinician and the researcher in the basic laboratory. The same pattern is shown in the discussion on respiratory, cardiac and neurological complications. The 14 chapters also include an overview of sickle cell disease especially in the paediatric age. The content is organized into well-designed broad sections on overview regarding diagnosis including point of care and the role of digital apps in patient management. A key aspect of the book is the opportunity it affords expert physicians to express well-reasoned opinions regarding complex issues in sickle cell disease. The readership would find that it provides a well-described, concise and immediate applicable answers to complex questions. This is highly recommended for scientists and clinicians alike.

Sickle cell anemia. --- Drepanocytic anemia --- Meniscocytosis --- Sickle cell disease --- Blood hyperviscosity syndrome --- Hemoglobinopathy --- Hemolytic anemia --- Medicine --- Hematology --- Hematopathology --- Health Sciences

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On average, black Americans are sicker and die earlier than white Americans. Uncertain Suffering provides a richly nuanced examination of what this fact means for health care in the United States through the lens of sickle cell anemia, a disease that primarily affects blacks. In a wide ranging analysis that moves from individual patient cases to the compassionate yet distanced professionalism of health care specialists to the level of national policy, Carolyn Moxley Rouse uncovers the cultural assumptions that shape the quality and delivery of care for sickle cell patients. She reveals a clinical world fraught with uncertainties over how to treat black patients given resource limitations and ambivalence. Her book is a compelling look at the ways in which the politics of racism, attitudes toward pain and suffering, and the reliance on charity for healthcare services for the underclass can create disparities in the U.S. Instead of burdening hospitals and clinics with the task of ameliorating these disparities, Rouse argues that resources should be redirected to community-based health programs that reduce daily forms of physical and mental suffering.

Sickle cell anemia --- Discrimination in medical care --- Health services accessibility --- Minorities --- Race discrimination --- Social medicine --- Drepanocytic anemia --- Meniscocytosis --- Sickle cell disease --- Blood hyperviscosity syndrome --- Hemoglobinopathy --- Hemolytic anemia --- Patients --- Medical care --- african americans. --- ambivalence. --- american healthcare system. --- anthropology. --- black americans. --- community based health programs. --- cultural assumptions. --- disease. --- doctor. --- health disparity. --- healthcare services. --- healthcare. --- human condition. --- life and death. --- medical treatment. --- medicine. --- mental suffering. --- national policy. --- pain and suffering. --- physical suffering. --- politics of racism. --- race in america. --- resource limitations. --- sicker. --- sickle cell anemia. --- sickle cell patients. --- sickness. --- symptoms. --- united states of america. --- wealth disparity.