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Book
The bioarchaeology of metabolic bone disease
Authors: --- ---
ISBN: 9780081022788 0081022786 0081010206 9780081010204 Year: 2020 Publisher: London, England : Academic Press,

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Book
Osteoporosis and Related Bone Metabolic Disease
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ISBN: 3036563490 3036563482 Year: 2023 Publisher: Basel, Switzerland : MDPI - Multidisciplinary Digital Publishing Institute,

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Many heterogeneous causes (e.g., metabolic, inflammatory, autoimmune, vascular, and renal diseases, and even drugs), collectively grouped as secondary causes of osteoporosis, may lead to bone loss or damage to architecture through a number of mechanisms. Although these secondary causes of osteoporosis are the most frequently observed causes of unexpected bone loss, they can only be diagnosed via a high degree of suspicion and clinical experience and by performing the appropriate investigations. In inflammatory disorders such as rheumatoid arthritis or chronic inflammatory bowel diseases, as well as vascular diseases, T-cell activation, and consequently pro-inflammatory cascades, trigger the increased expression of T-cell-derived RANKL. In addition, a new biomarker signature of bone-related miRNAs is promising in certain clinical features. Glucocorticoids, often used to control disease activity, decrease the number and function of osteoblasts and inhibit OPG expression. The ubiquitous occurrence of disease-related secondary changes in bone metabolism implies that numerous medical disciplines need to interact. Screening for secondary causes of osteoporosis and the search for new modes of action should present a substantial aspect of osteoporosis manageme.

Metabolic bone disease and clinically related disorders
Authors: ---
ISBN: 0120687003 9786611058906 1281058904 0080536271 9780120687008 9780080536279 Year: 1998 Publisher: Philadelphia : W.B. Saunders Co.,

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Metabolic Bone Disease, Third Edition is the new, expanded edition of the classic text, featuring the latest advancements and research information in this fast-moving field. The Third Edition includes the most up-to-date information on molecular mechanisms, basic biology, pathophysiology, and diagnosis and management strategies of metabolic bone disease.Key Features* Edited by ""fathers of the field""* An expanded version of a classic AP text* Complete coverage of a fast-growing field


Book
The bioarchaeology of metabolic bone disease
Authors: ---
ISBN: 1281308986 9786611308988 0080557910 0123704863 Year: 2008 Publisher: Amsterdam ; Boston : Elsevier/Academic Press,

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The Bioarchaeology of Metabolic Bone Disease provides a comprehensive and invaluable source of information on this important group of diseases. It is an essential guide for those engaged in either basic recording or in-depth research on human remains from archaeological sites. The range of potential tools for investigating metabolic diseases of bone are far greater than for many other conditions, and building on clinical investigations, this book will consider gross, surface features visible using microscopic examination, histological and radiological features of bone, that can be use


Periodical
Clinical cases in mineral and bone metabolism.
Authors: ---
ISSN: 19713266 Year: 2004 Publisher: Roma, Italy : CIC edizioni internazionali,

Dynamics of bone and cartilage metabolism
Authors: --- ---
ISBN: 9780120885626 012088562X 008045626X 9780080456263 9786610637850 1280637854 Year: 2006 Publisher: San Diego : Academic Press,

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This updated edition is a comprehensive treatise that spans the complete range of basic biochemistry of bone and cartilage components to the clinical evaluation of disease markers in bone and joint disorders. With contributions from over 75 international experts, this latest edition is indispensable reading for those involved in skeletal research as well as for rheumatologists, endocrinologists, clinical biochemists, and other clinical disciplines participating in the management of patients with bone and cartilage diseases.*Part I provides an up-to-date account of current knowledge of


Book
Osteoporosi e malattie metaboliche dell'osso : Clinica e diagnostica
Authors: ---
ISBN: 8847013569 9786612827877 8847013577 1282827871 Year: 2009 Publisher: Milano : Springer Milan : Imprint: Springer,

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L’osteoporosi è una complessa condizione patologica che può presentarsi in tutte le fasce di età, alla cui insorgenza concorrono molteplici fattori. Ne deriva pertanto la necessità di una rigorosa conoscenza eziopatogenetica fondamentale, oltre che clinica e diagnostica. Le conoscenze sempre più avanzate nel campo del metabolismo osseo, della clinica e farmacologia, hanno condizionato e reso necessario un adeguamento tecnico da parte dei medici specialisti ed in particolare del radiologo, in passato focalizzato sul solo aspetto diagnostico e oggi sempre più proiettato verso nuove prospettive di studio. L’opera si articola in sei parti distinte: dalla biologia, istologia e fisiopatologia del tessuto osseo (Parte I) si passa alla semeiotica, epidemiologia, fattori di rischio e prevenzione dell’osteoporosi (Parte II) e successivamente alla fisiopatologia, genetica e clinica dell’osteoporosi e delle malattie metaboliche dell’osso (Parte III). Di significativo impatto risulta la Parte IV, focalizzata sui diversi aspetti diagnostici dell’osteoporosi (diagnostica clinica, radiologica e di medicina nucleare) e resa ancora più preziosa da un’eccellente iconografia, quanto mai dimostrativa e scelta con rigorosa cura. Nella Parte V e nella Parte VI vengono infine trattati rispettivamente la terapia e le complicanze ortopediche e riabilitazione fisica. Si tratta di un testo chiaro, caratterizzato da una bibliografia precisa e aggiornata e da un’iconografia curata nei minimi particolari, da cui traspaiono l’esperienza e l’elevata capacità didattica degli Autori, sicuramente utile e interessante per tutti coloro che nell’ambito della propria attività professionale hanno necessità di approfondire le tematiche inerenti l’osteoporosi e le malattie del metabolismo osseo.


Periodical
JBMR : journal of bone and mineral research.
Author:
ISSN: 15234681 Year: 2024 Publisher: Oxford : Oxford University Press,

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The 'JBMR: Journal of Bone and Mineral Research' publishes highly impactful original manuscripts, reviews, and special articles on basic, translational and clinical investigations relevant to the musculoskeletal system and mineral metabolism. Specifically, the journal is interested in original research on the biology and physiology of skeletal tissues, interdisciplinary research spanning the musculoskeletal and other systems, and systems biology topics using large scale '-omics' approaches. The journal welcomes clinical research on the pathophysiology, treatment and prevention of osteoporosis and fractures, as well as sarcopenia, disorders of bone and mineral metabolism, and rare or genetically determined bone diseases.


Periodical
Bone.
Author:
ISSN: 18732763 Year: 1985 Publisher: Elmsford, NY : Pergamon,

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