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Book
Drug-Loaded Colloidal Systems in Nanomedicine II
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ISBN: 3036553592 3036553606 Year: 2022 Publisher: MDPI - Multidisciplinary Digital Publishing Institute

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This reprint highlights high-quality original research and review papers that include innovative colloidal drug delivery systems and cutting-edge characterization techniques that significantly contribute to the area of nanomedicine. The results presented are of high interest for specialists from a broad spectrum of fields, including biomedical, pharmaceutical, industrial, and biotechnological spheres.


Book
Electrospun Nanomaterials : Applications in Food, Environmental Remediation, and Bioengineering
Authors: ---
Year: 2020 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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The papers collected in this Special Issue entitled “Electrospun Nanomaterials: Applications in Food, Environmental Remediation, and Bioengineering” illustrate the high diversity and potential for implementation of electrospun nanofibers in these fields, including the covering of a wide number of subtopics. Examples of these applications have included bioactive scaffolds, wound healing dressings, compound protective nanoreservoirs and sustained and controlled release systems. An important driver of these applications results from advances in materials science and new nanofiber manufacturing processes. Definitely, such pieces of fundamental research will contribute to the promotion of electrospinning as a focal point in the future development of technological applications at the interface of biological systems, which promise long-term benefits for both health and the environment.


Book
Physiological and Pathological Role of ROS: Benefits and Limitations of Antioxidant Treatment
Authors: --- ---
Year: 2020 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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ROS were long considered one of the key players in tissue injury. Indeed, overproduction of ROS results in oxidative stress, a process leading to the development of many pathological conditions. For the treatment of these conditions, the use of antioxidants was proposed. Over time, it was shown that ROS at low concentrations act as signaling molecules, leading to the regulation of physiological functions. Moreover, several interventions that increase ROS generation activate stress-adaptive responses that extend the lifespan. It was also shown that excessive use of antioxidants can counter the beneficial effects of ROS. Currently, much progress has been made in understanding the role of ROS in human diseases and aging, as well as in the regulation of physiological functions, and in identifying the signaling pathways involved in ROS. However, much remains to be understood about the mutual interactions among signaling pathways underlying organisms’ adaptive responses, their modifications (which occur during aging), and some disease states. The aim of this Special Issue is to underline the effects of ROS production and antioxidant treatment in living organisms, focusing on their impact on health, disease, and aging.


Book
Functional Polymers as Innovative Tools in the Delivery of Antimicrobial Agents
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Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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This Special Issue explored different topics concerning recent progress in the synthesis and characterization of suitable innovative macromolecular systems, proposed as carriers of specific antimicrobial molecules, to be employed in the biomedical and pharmaceutical fields. Many infectious diseases are induced by omnipresent micro-organisms, including bacteria, viruses, protozoa, fungi, and algae, and, consequently, are very common, accounting for a significant share of the global disease burden. Unfortunately, antimicrobial resistance, adverse effects, and the high cost of antimicrobials are crucial health challenges worldwide. One of the common efforts in addressing this issue lies in improving the existing antimicrobial delivery systems. In this regard, nanoparticles as well as three-dimensional hydrophilic systems represent valuable tools able to ensure excellent performances. Biocompatible polymeric particles, entrapping these bioactive molecules, are capable of releasing them over a desired period of time, thereby decreasing the frequency of their administration. At the same time, these systems are able to protect antimicrobial drugs from degradation, enhancing their bioavailability. This Special Issue serves to highlight and capture the contemporary progress recorded in this field.


Book
Measurement Technologies for up- and Downstream Bioprocessing
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Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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This book is devoted to new developments in measurement technologies for upstream and downstream bioprocessing. The recent advances in biotechnology and bioprocessing have generated a number of new biological products that require more qualified analytical technologies for diverse process analytical needs. These includes especially fast and sensitive measurement technology that, early in the process train, can inform on critical process parameters related to process economy and product quality and that can facilitate ambitions of designing efficient integrated end-to-end bioprocesses. This book covers these topics as well as analytical monitoring methods based either on real-time or in-line sensor technology, on simple and compact bioanalytical devices, or on the use of advanced data prediction methods.


Book
Electrospun Composite Nanofibers for Functional Applications
Authors: --- ---
Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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This reprint includes research articles on various applications of electrospun nanofibers. Nanofibers have potential to be used in tissue engineering, energy harvesting, sensors, separators, water filtration, air filtration, and other applications as well. This Special Issue has received 11 interesting research articles, which covers such application areas.


Book
Drug Delivery Systems Based on Polysaccharides
Authors: ---
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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We live in a constantly changing society, in which life expectancy has continuously increased, and, therefore, important health issues need to be solved. The development of nanotechnology with applications in the medical field—nanomedicine—has been proven to have strong therapeutic potential, especially by combining drugs with natural polymers, polysaccharides being most commonly used in the development of sustained and controlled release systems of biologically active principles. Polymeric nanoparticles loaded with drugs can actively target various diseases, being able to penetrate cells more effectively or succeed in overcoming some physiological barriers such as the blood–brain barrier. Drug-loaded hydrogels are used to treat dermal and dental conditions, and can act as scaffolds for the development of cell cultures with applications in tissue engineering. The recent literature abounds with articles discussing aspects of obtaining new polymer drug systems and their use in various biomedical applications. The editors of this Special Issue of the journal Molecules, entitled Drug Delivery Systems Based on Polysaccharides, are researchers with decades of experience in this field, and they consider justified and useful these several articles which report recent results of drug delivery systems based on polysaccharides and derivatives, respectively, and their biomedical applications. The authors of the articles are experts in the field, and the editors express their gratitude for the kindness and promptness with which they responded to the call to contribute the recently obtained results of their research to this specific edition of the journal Molecules.


Periodical
Biopolimery i kletka
Author:
ISSN: 02337657 19936842

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Periodical
Molecular cell.
ISSN: 10974164 10972765 Year: 1997 Publisher: [Cambridge, Mass.] : Cell Press,

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Book
Promising Detoxification Strategies to Mitigate Mycotoxins in Food and Feed
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ISBN: 3038970271 303897028X Year: 2018 Publisher: MDPI - Multidisciplinary Digital Publishing Institute

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This book is a printed edition of the Special Issue Promising Detoxification Strategies to Mitigate Mycotoxins in Food and Feed that was published in Toxins

Keywords

Trichoderma --- n/a --- photodegradation product --- physical decontamination --- growth performance --- toxigenic Fusarium --- curcumin --- mitigation --- Aspergillus flavus --- food and beverage --- ascladiol --- biological control --- antioxidant capability --- trichothecene --- bioprospecting --- turkey --- processing --- chicks --- Sporobolomyces sp. IAM 13481 --- mycotoxins --- epimer --- Tri101 --- enzymes --- neutral electrolyzed water --- antioxidant function --- purification --- ameliorating effects --- aflatoxin-degrading enzyme --- chemical decontamination --- desoxypatulinic acid --- furan rings --- maize --- atmospheric pressure --- biotransformation --- estrogen receptor (ER) --- oxidative stress --- decontamination --- Bacillus shackletonii --- hyssop --- DBD --- degradation --- TQEF-MS/MS --- CYP450 --- enzymatic detoxification --- low temperature plasma --- Fusarium --- AFBO–DNA --- modified mycotoxin --- Bacillus subtilis ANSB060 --- polarity --- thermal treatment --- serum hormones --- mycotoxins mitigation --- mycotoxin --- zearalenone (ZEA) --- cell viability --- detoxification --- patulin --- biodegradation --- interactions --- intracellular and extracellular enzymes --- Bacillus licheniformis CK1 --- deoxynivalenol --- aflatoxins --- aflatoxin B1 --- biological decontamination --- Corylus avellana --- molecular --- Pichia caribbica --- mild technologies --- microbial patulin degradation --- enzyme --- proteomics --- fatty acids --- spores of Ganoderma lucidum --- inhibition --- residue --- food safety --- cold atmospheric pressure plasma technology --- application --- post-weaning female piglets --- laccase --- aflatoxin biodegradation preparation --- Aflatoxin B1 --- microorganism identification --- AFBO-DNA

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