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Urologic cancers are an umbrella term for cancers of the prostate, kidney, bladder, penis, and testis. Routine use of advanced imaging modalities for various reasons has increased the incidental detection of some of these cancers at an early stage. Robot-assisted surgery for nephrectomy, prostatectomy, cystectomy, and retroperitoneal lymph node dissection have improved surgical outcomes of localized disease. The introduction of targeted therapies since 2006 has revolutionized the management of metastatic kidney cancer. Despite these advances, the five-year survival of patients with advanced renal cancer is still poor and we need a better understanding of the disease. The book Urologic Cancers brings together an international team of clinicians and basic scientists to provide an up-to-date overview of a wide spectrum of topics that comprise epidemiological, pathological, clinical, and biological aspects of urologic cancers. From the epidemiological spectrum, the most recent information on the epidemiology of testicular cancer and penile cancer are presented. From the clinical spectrum, the characteristics and management of divergent urothelial neoplasms, the role of surgery in the management of testicular and kidney cancer, biopsy approaches for better detection and diagnosis of prostate cancer, the role of family history and germline genetics in prostate cancer disease profiling and screening, and the need for the implementation of quality assurance programs to improve prostate cancer care discussed. The biological aspects of disease mechanisms focus on various emerging molecular pathways and how these can be targeted to develop novel therapeutics. The contents of the book will be of interest to healthcare professionals, basic scientists and clinicians interested in urologic cancers.
urologic cancers --- prostate cancer --- kidney cancer --- testicular cancer --- bladder cancer --- penile cancer --- Urologic Neoplasms. --- Testicular Neoplasms. --- Penile Neoplasms. --- Kidney Neoplasms. --- Urinary Bladder Neoplasms.
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Male Reproductive Cancers: Epidemiology, Pathology and Genetics presents a thoughtful, comprehensive and up-to-date overview of the etiology of the prostate gland and the testes, summarizing decades of research in the three most important etiological disciplines: epidemiology, pathology and genetics. This book is comprised of four distinct sections: Epidemiology, Pathology, Molecular Genetics, and Inherited Susceptibility, with each section divided into chapters categorized by disease. Section A reviews the epidemiology of prostate and testicular cancer, with an emphasis on clinical and environmental factors associated with these diseases. Section B begins by describing various pathological features of prostate cancer, followed by descriptions of the wide variety of testicular cancers as well as a brief section on the use of tumor markers for monitoring disease. Section C focuses on somatic genetic changes in prostate and testicular cancers using new technologies such as comparative genomic hybridization and gene expression profiling. Section D concentrates on the progress made toward understanding inherited susceptibility to prostate cancer and to testicular cancer.
Generative organs, Male -- Cancer -- Genetic aspects. --- Generative organs, Male -- Cancer. --- Generative organs, Male --- Prostatic Neoplasms --- Testicular Neoplasms --- Germinoma --- Neoplasms, Germ Cell and Embryonal --- Genital Neoplasms, Male --- Endocrine Gland Neoplasms --- Testicular Diseases --- Prostatic Diseases --- Genital Diseases, Male --- Endocrine System Diseases --- Urogenital Neoplasms --- Neoplasms by Site --- Gonadal Disorders --- Neoplasms by Histologic Type --- Male Urogenital Diseases --- Neoplasms --- Diseases --- Oncology --- Medicine --- Health & Biological Sciences --- Cancer --- Genetic aspects --- Genetic aspects. --- Cancer. --- Male generative organs --- Male generative tract --- Male genital system --- Male genital tract --- Male genitalia --- Male reproductive system --- Male reproductive tract --- Medicine. --- Cancer research. --- Human genetics. --- Oncology. --- Biomedicine. --- Cancer Research. --- Human Genetics. --- Cancer in men --- Andrology --- Generative organs --- Oncology . --- Genetics --- Heredity, Human --- Human biology --- Physical anthropology --- Tumors --- Cancer research
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