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From patient referral to post-therapy management, Chimeric Antigen Receptor (CAR) T-Cell Therapies for Cancer: A Practical Guide presents a comprehensive view of CAR modified T-cells in a concise and practical format. Providing authoritative guidance on the implementation and management of CAR T-cell therapy from Drs. Daniel W. Lee and Nirali N. Shah, this clinical resource keeps you up to date on the latest developments in this rapidly evolving area. Covers all clinical aspects, including patient referral, toxicities management, comorbidities, bridging therapy, post-CAR monitoring, and multidisciplinary approaches to supportive care. Includes key topics on associated toxicities such as predictive biomarkers, infections, and multidisciplinary approaches to supportive care. Presents current knowledge on FDA approved CAR T-cell products as well as developments on the horizon. Editors and authors represent leading investigators in academia and worldwide pioneers of CAR therapy.
Oncology. Neoplasms --- T cells --- Tumor antigens. --- Receptors, Chimeric Antigen --- Neoplasms --- Immunotherapy, Adoptive. --- Receptors, Antigen, T-Cell. --- Cell- and Tissue-Based Therapy. --- Receptors. --- therapeutic use. --- therapy.
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The T Cell Receptor FactsBook contains entries on all the 176 functional variable, diversity, joining, and constant regions of the human T cell receptor, including alpha, beta, gamma, and delta loci. Introductory chapters summarize information of T cell receptor chain synthesis, chromosomal location, and an overview of the human T cell receptor loci.
T cells. --- T cells Receptors--Handbooks, manuals, etc. T-cell receptor genes--Handbooks, manuals, etc. --- T-cell receptor genes. --- Receptors, Antigen, T-Cell --- Genes, T-Cell Receptor --- Genes --- Receptors, Antigen --- Genome Components --- Receptors, Immunologic --- Receptors, Cell Surface --- Genome --- Membrane Proteins --- Genetic Structures --- Proteins --- Genetic Phenomena --- Amino Acids, Peptides, and Proteins --- Phenomena and Processes --- Chemicals and Drugs --- Microbiology & Immunology --- Biology --- Health & Biological Sciences --- T cells --- T-cell receptor genes --- Receptors --- T lymphocytes --- Thymus-dependent cells --- Thymus-dependent lymphocytes --- Thymus-derived cells --- Lymphocytes
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Immunotherapy. --- Cancer --- Genetic engineering. --- Treatment. --- T cells. --- Neoplasms --- Receptors, Antigen, T-Cell --- T-Lymphocytes --- Immunotherapy, Adoptive. --- therapy. --- therapeutic use. --- immunology. --- Adoptive Immunotherapy --- CAR T-Cell Therapy --- Cellular Immunotherapy, Adoptive --- Chimeric Antigen Receptor Therapy --- Immunotherapy, Adoptive Cellular --- Adoptive Cellular Immunotherapy --- Adoptive Cellular Immunotherapies --- Adoptive Immunotherapies --- CAR T Cell Therapy --- CAR T-Cell Therapies --- Cellular Immunotherapies, Adoptive --- Immunotherapies, Adoptive --- Immunotherapies, Adoptive Cellular --- T-Cell Therapies, CAR --- T-Cell Therapy, CAR --- Therapies, CAR T-Cell --- Therapy, CAR T-Cell --- Receptors, Chimeric Antigen --- Killer Cells, Lymphokine-Activated --- Cytapheresis --- Lymphocytes, Tumor-Infiltrating --- Monocytes, Activated Killer --- Designed genetic change --- Engineering, Genetic --- Gene splicing --- Genetic intervention --- Genetic surgery --- Genetic recombination --- Biotechnology --- Transgenic organisms --- Cancer therapy --- Cancer treatment --- Therapeutic immunology --- Clinical immunology --- Therapeutics --- T lymphocytes --- Thymus-dependent cells --- Thymus-dependent lymphocytes --- Thymus-derived cells --- Lymphocytes --- Therapy --- Immunological aspects --- Treatment
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