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Amyloid protein aggregates are involved in ''protein-misfolding diseases'' of enormous social and economic impact, still with no effective therapies. The most prevalent amyloid pathologies are related to neurodegenerative diseases, but amyloidosis also affects other organs. The majority of the studies includes serious health connotations on amyloids. However, not all amyloid fibers play a detrimental role in host. An increasing number of studies shows an important beneficial role as ''functional amyloids''. This book opens an exciting door to provide up-to-date information about the function and the mechanisms of the amyloid formation process from the structural, biophysical, biomedical, and nanotechnological perspective, combining the new findings on toxic and functional amyloids studies using theoretical and experimental approaches to fight against amyloid-based diseases.
Amyloidosis. --- Amyloid degeneration --- Lymphoproliferative disorders --- Proteins --- Metabolism --- Disorders --- Cardiovascular medicine
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Amyloidosis. --- Amyloid degeneration --- Lymphoproliferative disorders --- Proteins --- Metabolism --- Disorders
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Amyloidosis is a benign, slowly progressive condition characterized by the presence of extracellular fibrillar proteins in various organs and tissues. It has systemic or localized forms. Both systemic and localized amyloidosis have been a point of interest for many researchers and there have been a growing number of case reports in the literature for the last decade. The aim of this book is to help the reader become familiar with the presentation, diagnosis and treatment modalities of systemic and localized amyloidosis of specific organs or systems and also cover the latest advancements in therapy.
Amyloidosis. --- Amyloid degeneration --- Lymphoproliferative disorders --- Proteins --- Metabolism --- Disorders --- Infectious & contagious diseases
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Amyloidoses are a heterogeneous group of diverse etiology diseases. They are characterized by an endogenous production of abnormal proteins called amyloid proteins, which are not hydrosoluble, form depots in various organs and tissue of animals and humans and cause dysfunctions. Despite many decades of research, the origin of the pathogenesis and the molecular determinants involved in amyloid diseases has remained elusive. At present, there is not an effective treatment to prevent protein misfolding in these amyloid diseases. The aim of this book is to present an overview of different aspects of amyloidoses from basic mechanisms and diagnosis to latest advancements in treatment.
Amyloidosis. --- Amyloid degeneration --- Lymphoproliferative disorders --- Proteins --- Metabolism --- Disorders --- Infectious & contagious diseases
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Neurodegenerative diseases are severe, rapidly developing, and currently incurable conditions that result in progressive degeneration and the death of neurons. This causes dementia, movement problems, and essentially loss of personal identity. Amyloids attempts to answer the following questions: (1) why do we develop these severe neurodegenerative diseases? (2) what histological and physiological changes are observed upon development and progression of these diseases? and (3) how can we treat amyloid-associated diseases?
Amyloidosis --- Diagnosis. --- Amyloid degeneration --- Lymphoproliferative disorders --- Proteins --- Metabolism --- Disorders --- Medicine --- Endocrinology --- Health Sciences
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Amyloidosis is an uncommon disorder characterized by the deposition of extracellular amyloid proteins in tissues. Significant advancement has been made recently, which not only provides insight in to the pathophysiology of the disease but also helps to discover new therapies to fight the deadly disease. If accurate diagnosis and typing are made early, effective or even curative therapies are available. Unfortunately, because of the rarity of the disease and its protean clinical manifestations, patients may be misdiagnosed, especially at early stage of the disease, and this could lead to missed opportunities to effective therapy. The aim of the book is to help readers become familiar with the clinical presentation of amyloidosis and to review the latest diagnostic and therapeutic development.
Amyloidosis. --- Amyloid degeneration --- Lymphoproliferative disorders --- Proteins --- Metabolism --- Disorders --- Infectious & contagious diseases
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Authoritative reviews and updates discuss recent advances in radiation therapy in treatment of Hodgkins lymphoma, B-cell nodal and extranodal lymphomas, follicular lymphoma and cutaneous T-cell lymphoma; mantle cell lymphoma, and leukemia. In addition, reviews of current developments in PET imaging in lymphoma, radioimmunotherapy, and radiation and transplant, are included. This volume of Radiation Medicine Rounds gives the radiation oncology professional a complete overview of current best practice and emerging modalities for radiation treatment of hematologic malignancies.Hematologic Maligna
Lymphoproliferative disorders. --- Immunoproliferative disorders --- Lymphoproliferative syndrome --- Cell proliferation --- Immunological deficiency syndromes --- Lymphatics --- Lymphomas --- Diseases
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Lymphoproliferative disorders --- Immunoproliferative disorders --- Lymphoproliferative syndrome --- Cell proliferation --- Immunological deficiency syndromes --- Lymphatics --- Lymphomas --- Diseases
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Leukemia, Lymphoid --- Chronic Disease --- Waldenström Macroglobulimenia --- Lymphocytic leukemia. --- Lymphoproliferative disorders. --- Immunoproliferative disorders --- Lymphoproliferative syndrome --- Cell proliferation --- Immunological deficiency syndromes --- Lymphatics --- Lymphomas --- Leukemia, Lymphocytic --- Lymphatic leukemia --- Lymphoid leukemia --- Leukemia --- Lymphoproliferative disorders --- Diseases
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The Third Edition of Knowles Neoplastic Hematopathology has been thoroughly updated by the world's experts to cover all aspects of neoplastic hematopathology, a field that covers disorders of the bone marrow, spleen, and lymphatic system. Now in full-color, this completely revised and expanded edition integrates the basic science, modern diagnostic techniques, and clinical aspects of malignant diseases affecting these organs. It is the most comprehensive, encyclopedic textbook concerning neoplastic hematopathology available on the market today.
Lymphoproliferative disorders --- Hematopoietic system --- Hematopoietic system. --- Bone marrow --- Hemopoietic system --- Hematopoiesis --- Immunoproliferative disorders --- Lymphoproliferative syndrome --- Cell proliferation --- Immunological deficiency syndromes --- Lymphatics --- Lymphomas --- Cytopathology. --- Cancer --- Diseases. --- Diseases --- Hematopoietic System --- Bone Marrow Diseases --- Hematologic Neoplasms --- Leukemia --- Lymphoproliferative Disorders --- pathology
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