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Although there have been significant advancements in minimally invasive spinal surgery techniques in the last few decades, optimal outcomes for chronic low back pain remain elusive. A number of promising clinical trials have been conducted using tissue engineering and biological interventions for disc degeneration. Written by renowned innovators, this is the first book that covers implementation of these groundbreaking approaches for disc disease. The text begins with key fundamentals including anatomy and physiology, pathophysiology, imaging and biomechanics to delineate healthy versus diseased spine. Subsequent sections discuss treatment strategies, research findings, and future developments. Throughout each chapter, renowned spine surgeons and scientists share clinical pearls gleaned from hands-on experience.

Intervertebral Disc Degeneration --- Complications.

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

Epilepsy --- MRI - Magnetic resonance imaging --- Chiari --- Syringomyelia (syrinx) --- Intervertebral Disc --- Glioma --- Ventriculomegally --- SPECT (single photon emission tomography) --- PET - Positron Emission Tomography --- Encephalitis --- Meninges

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This book collects the articles published in the Special Issue “Polymeric Materials: Surfaces, Interfaces and Bioapplications”. It shows the advances in polymeric materials, which have tremendous applications in agricultural films, food packaging, dental restoration, antimicrobial systems, and tissue engineering. These polymeric materials are presented as films, coatings, particles, fibers, hydrogels, or networks. The potential to modify and modulate their surfaces or their content by different techniques, such as click chemistry, ozonation, breath figures, wrinkle formation, or electrospray, are also explained, taking into account the relationship between the structure and properties in the final application. Moreover, new trends in the development of such materials are presented, using more environmental friendly and safe methods, which, at the same time, have a high impact on our society.

Artificial muscle --- chitosan --- graphene oxide --- antifouling coatings --- tissue engineering --- biodegradable --- polymer cross-linking --- UV/ozone --- inmiscibility --- bioapplications --- antibacterial --- polypropylene --- degradation --- protein-repellent polymer --- micro- and nanopatterned films --- oral biofilms --- bio-based --- composite films --- stimuli-responsive materials/smart surfaces --- surface modification/functionalization --- caries inhibition --- superhydrophobic --- blends --- nanosecond laser surface modification --- biofouling --- degenerative disc disease --- surface-attached polymer network --- total disc replacement --- surface wettability --- bonding agents --- polydimethylsiloxane --- natural biofilms --- Electrical stimulation --- microparticles --- hemicelluloses --- superhydrophilic --- fossil --- surface segregation --- honeycomb --- prolonged drug release --- hydrogel --- conformational entropy --- Electroactive biomaterials --- antimicrobial --- ABS (Acrylonitrile-Butadiene-Styrene) --- intervertebral disc --- calcium chloride --- sustainable --- biodegradable polymers --- friction and wear --- Drug delivery --- alginate modification --- breath figures --- spinal fusion --- blends and (nano)composites --- composites --- antimicrobial polymer --- periodontal pathogens --- polymeric composites --- scaffolds --- corn stalk fiber --- worn surface morphology --- irradiance --- friction composite --- antimicrobial coatings --- gradient wrinkles --- porous surfaces --- Electrically conductive polymers --- oxygen barrier property --- food packaging --- spinal anatomy --- Smart composites --- recycling --- packaging --- hybrids --- bio-based polymers --- coatings --- poly(x-chlorostyrene) --- eco-friendly --- multidimensional scale analysis --- single-stranded conformation polymorphism --- Bioelectric effect --- spray drying --- herniated disc