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Improving psychological well-being and cognitive health is now listed as the priority on the healthy aging agenda. Depression and cognitive impairment are great challenges for the elderly population. There have been numerous studies on depression and cognitive impairment and dementia. However, the neural correlates of depression and cognitive impairment have not yet been elucidated. With the development of neuroscience and relevant technologies, studies on anatomical and functional neural networks, neurobiological mechanisms of mood and cognition in old age will provide more insight into the potential diagnosis, prevention and intervention in depression and cognitive impairment. For example, longitudinal neuroimaging studies depicting the trajectories of patterns of structural and functional brain networks of mild cognitive impairment may provide potential imaging markers for the onset of dementia. Population-based studies have addressed the potential interaction between mood and cognitive impairment in old age. However, there are few studies to explore the potential neural mechanism of the relationship between depression and cognitive impairment in old age. In all of this process the contribution of multiple biological events cannot be neglected, particularly the underlying influence of chronic diseases and concomitant polymedication as well as the geriatric conditions, like frailty, frequently present in this elderly population, which also compromise the cognitive function and mood determining depression and conducing to worse outcomes with more morbidity and mortality.

mood disorder --- mild cognitive impairment --- Alzheimer

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'A Personal Guide to Living with Progressive Memory Loss serves as a commitment to inclusive education and is a landmark self-help book that focuses on the needs of the person with the diagnosis. It expands what is currently offered to people with memory loss in a sensitive and contemporary way. A must have for every memory clinic and health and human service agency.'. - Linda L. Buettner, Professor at the University of North Carolina at Greensboro, Alzheimer's Association Early Stage Task Force. 'This book empowers people living with dementia, signposting hope, choice and a life to be lived.

Memory disorders --- Impairment, Memory --- Memory, Disorders of --- Memory impairment --- Paramnesia --- Cognition disorders --- Prevention

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Dementia --- Mild cognitive impairment. --- Cognition disorders --- Cognitive disorders --- Psychology, Pathological --- Cognitive impairment, Mild --- Impairment, Mild cognitive --- MCI (Mild cognitive impairment) --- Treatment. --- Diagnosis. --- Cognitive Dysfunction. --- Aging. --- diagnosis. --- therapy. --- Aging --- diagnosis --- therapy

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Traumatic brain injury (TBI) is a nondegenerative, noncongenital insult to the brain from an external mechanical force, possibly leading to permanent or temporary impairment of cognitive, physical, and psychosocial functions, with an associated diminished or altered state of consciousness. The definition of TBI has not been consistent and tends to vary according to specialties and circumstances. The term brain injury is often used synonymously with head injury, which may not be associated with neurological deficits. The definition has also been problematic due to variations in inclusion criteria. Both American and Brazilian data indicate that more than 700,000 people suffer TBI annually, with 20% afflicted with moderate or severe TBI. According to this data, 80% of people who suffered mild TBI can return to work, whist only 20% of moderate, and 10% of victims of severe TBI can return to their daily routine. Cognitive rehabilitation, a clinical area encompassing interdisciplinary action aimed at recovery as well as compensation of cognitive functions, altered as a result of cerebral injury, is extremely important for these individuals. The aim of a cognitive and motor rehabilitation program is to recover an individual's ability to process, interpret and respond appropriately to environmental inputs, as well as to create strategies and procedures to compensate for lost functions that are necessary in familial, social, educational and occupational relationships. In general, the cognitive rehabilitation programs tend to focus on specific cognitive domains, such as memory, motor, language and executive functions. By contrast, the focus of compensatory training procedures is generally on making environmental adaptations and changes to provide grater autonomy for patients. Successful cognitive rehabilitation programs are those whose aim is both recovery and compensation based on an integrated and interdisciplinary approach. The purpose of this Research Topic is to review the basic concepts related to TBI, including mechanisms of injury, severity levels of TBI, the most common findings in mild, moderate and severe TBI survivors, and the most cognitive and motor impairments following TBI, and also to discuss the strategies used to handle patients post-TBI. Within this context, the importance of an interdisciplinary rehabilitation for TBI is underlined.

Traumatic Brain Injury --- Diffuse Axonal Injury --- concussion --- cognitive impairment

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Specific Language Impairment (SLI) may be best thought of as probabilisticallydetermined by multiple risk and protective factors. It follows from this that theunderlying deficits in SLI may vary requiring different approaches to treatmentand allowing for the possibility of different strengths or facilitative effects. Notsurprisingly, a range of interventions have been developed. This chapter reviewsavailable approaches and evidence in light of theories related to SLI deficits indomain-specific or domain-general processes, and evidence tapping potentialprotective factors related to SLI. Finally

Specific language impairment in children. --- SLI (Specific language impairment) in children --- Specific language disability in children --- Language disorders in children