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A complete account of the theory of the diffraction of X-rays by crystals, with particular reference to the processes of determining the structures of protein molecules. This book is aimed primarily at structural biologists and biochemists but will also be valuable to those entering the field with a background in physical sciences or chemistry. It may be used at any post-school level, and develops from first principles all relevant mathematics, diffraction and wave theory, assuming no mathematical knowledge beyond integral calculus. The book covers a host of important topics in the area, including: * The practical aspects of sample preparation and X-ray data collection, using both laboratory and synchrotron sources * Data analysis at both theoretical and practical levels * The important role played by the Patterson function in structure analysis, by both molecular replacement and experimental phasing approaches * Methods for improving the resulting electron density map* The theoretical basis of methods used in refinement of protein crystal structures * In-depth explanation of the crucial task of defining the binding sites of ligands and drug molecules * The complementary roles of other diffraction methods: these reveal further detail of great functional importance in a crystal structure.

Chemical and physical crystallography --- fysicochemie --- X-Rays --- Proteins --- Science --- X-rays

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Rocks. Minerals --- General biochemistry --- Chemical and physical cristallography --- Crystallography --- Crystals --- Cristallographie --- Cristaux --- Periodicals --- Periodicals. --- Périodiques --- Crystallography. --- Crystals. --- biochemie --- Leptology --- Crystallographies --- crystal structure determination --- crystal engineering --- structural chemistry --- Powders --- Solids --- Physical sciences --- Mineralogy --- Chemistry --- Materials Science --- Chemical and physical crystallography

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Mineralogy --- Mineralogie. --- Minéralogie --- Cristallographie --- #TS:WAAR --- Allemagne, France --- Periodicals --- E-journals --- Chemistry --- Earth Sciences --- Material Science and Metallurgy --- Crystallography --- General and Others --- Geology --- Metals, Minerals, Ores & Alloys --- Minéralogie --- Mineralogy. --- Physical geology --- Minerals --- mineralogy --- geochemistry --- petrology --- crystallography --- ore deposits --- Chemical and physical crystallography --- Rocks. Minerals --- fysicochemie

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661.14 <063> --- 661.14 <063> Photochemical materials (other than plates, films, papers)--Congressen --- Photochemical materials (other than plates, films, papers)--Congressen --- Chemical and physical cristallography --- Rocks. Minerals --- fysicochemie --- Chemical and physical crystallography --- Molecular crystals --- Liquid crystals --- Cristaux moléculaires --- Cristaux liquides --- Crystals, Liquid --- Light sources --- Molecules --- Chemistry --- Physics --- Analytical Chemistry --- Crystallography --- General and Others

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Rocks. Minerals --- fysicochemie --- Chemical and physical cristallography --- Crystallography --- Cristallographie --- Periodicals --- Périodiques --- Cristallographie. --- #TS:TMTS --- #TS:WMAG --- 55 --- Earth sciences. Geology. Meteorology etc. --- Chemistry --- Analytical Chemistry --- Applied Chemistry --- Physical Chemistry --- Information Science and Systems --- Information Technology --- General and Others --- Chemistry. --- Information Science and Systems. --- Information Technology. --- 55 Earth sciences. Geology. Meteorology etc. --- Journal --- 55 Aardwetenschappen. Geowetenschappen. Geologie. Meteorologie. Weerkunde --- Aardwetenschappen. Geowetenschappen. Geologie. Meteorologie. Weerkunde --- Chemical and physical crystallography --- Crystallography - Periodicals.