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Short non-coding RNA molecules, microRNAs (miRNAs), post-transcriptionally regulate gene expression in living cells. In recent years, miRNAs have been found in a wide spectrum of mammalian body fluids including blood plasma, saliva, urine, milk, seminal plasma, tears and amniotic fluid as extracellular circulating nuclease-resistant entities. The changes in miRNA spectra observed in certain fluids correlated with various pathological conditions suggesting that extracellular miRNAs can serve as informative biomarkers for certain diseases including cancer. However, the mechanism of generation and a biological role of extracellular miRNAs remain unclear. The current theories regarding extracellular miRNA origin and function suggest that these miRNAs can be either non-specific 'by-products' of cellular activity and cell death or specifically released cell-cell signaling messengers. The goal of this Research Topic is to bring together up-to-date knowledge about the extracellular miRNA and its role in disease diagnostics and, possibly, inter-cellular communication.
MicroRNA. --- Blood plasma. --- Blood --- Genetics. --- Epigenetics. --- Diseases. --- extracellular miRNA --- exosomal miRNA --- blood plasma --- blood serum --- circulating miRNA --- Argonaute Proteins --- cell-cell communication --- biological fluids
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Dextran. --- Fermentation gum --- Blood plasma substitutes --- Carbohydrates --- Glucans --- Glucose --- Sugar --- Manufacture and refining --- By-products
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Blood substitutes are solutions designed for use in patients who need blood transfusions, but for whom whole blood is not available, or is not safe. This interest has intensified in the wake of the AIDS and hepatitis C epidemics. Blood Substitutes describes the rationale, current approaches, clinical efficacy, and design issues for all blood substitutes now in clinical trials. The many summary diagrams and tables help make the book accessible to readers such as surgeons and blood bankers, who have less technical expertise than the biochemists and hematologists who are designing and test
Blood substitutes. --- Blood plasma substitutes. --- Blood expanders --- Plasma substitutes --- Plasma volume expanders --- Blood plasma --- Hematologic agents --- Artificial blood --- Erythrocyte substitutes --- Hemoglobin substitutes --- Oxygen-transport fluids (Hematology) --- Red cell substitutes --- Synthetic blood --- Blood products --- Transfusion-free surgery
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This publication aims to provide practical guidance to all those involved in the management of blood programmes. Following an introduction to the blood cold chain management process, seven chapters provide a detailed description of blood bank refrigerators, plasma freezers, platelet agitators, plasma thawing equipment, blood transport boxes and coolants, temperature monitoring devices, as well as other blood cold chain accessories. Each chapter provides WHO minimum performance specifications for the equipment, and selected product information on equipment evaluated by WHO. A specific chapter i
Bloedplaatjes --- Bloedplasma --- Blood plasma --- Blood platelets --- Blood--Plasma --- Plaatjes [Bloed] --- Plaquettes sanguines --- Plasma (Bloed) --- Plasma (Blood) --- Plasma (Sang) --- Plasma sanguin --- Platelets --- Thrombocytes --- Trombocyten --- Blood. --- Blood --- Blood banks --- Hematologic equipment industry --- Tissue Preservation --- Preservation, Biological --- Biological Specimen Banks --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Blood Cells --- Health Facilities --- Investigative Techniques --- Body Fluids --- Cells --- Specimen Handling --- Laboratory Techniques and Procedures --- Fluids and Secretions --- Anatomy --- Health Care Facilities, Manpower, and Services --- Diagnosis --- Health Care --- Refrigeration --- Blood Platelets --- Blood Banks --- Blood Preservation --- Equipment and Supplies --- Plasma --- Medicine --- Health & Biological Sciences --- Hematologic Diseases --- Equipment and supplies --- Collection and preservation --- Transfusion --- Refrigerators. --- Equipment and supplies. --- Refrigeration and refrigerating machinery --- Body fluids --- Fear of blood --- Standards --- Guidebooks
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Complement has long been regarded as a pivotal effector arm of the innate im-mune response, eliciting important immunoregulatory functions in the context of inflammation and also serving as a vital link between the innate and adaptive immune response. In the post-genomic era, our knowledge of the innate immune system is enriched by findings that point to novel functions that do not strictly correlate with immunological defense and surveillance, immune modulation or inflammation. Several studies indicate that complement proteins exert functions that are either more complex than previously thought, or go well beyond the innate immune character of the system. The advent of high-throughput platforms for genome and proteome-wide profiling, together with the enormous amount of raw genetic information that has accumulated in the databases, have stirred new expectations in biomedical research. They have led complementologists to revisit established biological systems, such as the complement system, from a global and integrative perspec-tive. Complement research is now faced with the challenge of trying to integrate isolated biochemical pathways into complex gene and protein regulatory cir-cuits. In this respect, scientists from around the world convened at the Third Aegean Conferences Workshop on Complement Associated Diseases, Animal Models, and Therapeutics (June 5–10, 2005), to discuss recent advances in this fast evolving field. This volume represents a collection of topics on the "novel" functions of complement, pathophysiology, protein structures, design of complement inhibitors, and complement assays discussed during the conference.
Complement (Immunology) --- Blood proteins. --- Plasma proteins --- Serum proteins --- Blood plasma --- Proteins --- Serum --- Alexin --- Complements (Immunity) --- Blood proteins --- Immunology. --- Microbiology. --- Emerging infectious diseases. --- Pathology. --- Infectious Diseases. --- Disease (Pathology) --- Medical sciences --- Diseases --- Medicine --- Medicine, Preventive --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Microbial biology --- Biology --- Microorganisms --- Immunobiology --- Life sciences --- Serology --- Infectious diseases.
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Polysaccharides. --- Polysaccharides --- Cellulose --- Dextran --- Organic Chemistry --- Chemistry --- Physical Sciences & Mathematics --- Cellulose. --- Dextran. --- Fermentation gum --- Chemistry. --- Organic chemistry. --- Polymers. --- Biochemistry. --- Polymer Sciences. --- Organic Chemistry. --- Biochemistry, general. --- Blood plasma substitutes --- Carbohydrates --- Glucans --- Glucose --- Sugar --- Wood --- Manufacture and refining --- By-products --- Chemistry, Organic. --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Medical sciences --- Organic chemistry --- Polymere --- Polymeride --- Polymers and polymerization --- Macromolecules --- Composition --- Polymers .
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Low temperature plasmas --- Plasma. --- Therapeutic use. --- Blood Plasma --- Fresh Frozen Plasma --- Blood Plasmas --- Fresh Frozen Plasmas --- Frozen Plasma, Fresh --- Frozen Plasmas, Fresh --- Plasma, Blood --- Plasma, Fresh Frozen --- Plasmas --- Plasmas, Blood --- Plasmas, Fresh Frozen --- Serum --- Cold plasmas --- Plasmas, Low temperature --- Plasma (Ionized gases)
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The Foundations of Vacuum Coating Technology, Second Edition, is a revised and expanded version of the first edition, which was published in 2003. The book reviews the histories of the various vacuum coating technologies and expands on the history of the enabling technologies of vacuum technology, plasma technology, power supplies, and low-pressure plasma-enhanced chemical vapor deposition. The melding of these technologies has resulted in new processes and products that have greatly expanded the application of vacuum coatings for use in our everyday lives. The book is unique in that it makes extensive reference to the patent literature (mostly US) and how it relates to the history of vacuum coating. The book includes a Historical Timeline of Vacuum Coating Technology and a Historical Timeline of Vacuum/Plasma Technology, as well as a Glossary of Terms used in the vacuum coating and surface engineering industries.
Manufacturing processes --- Vacuum. --- Plasma. --- Vacuum technology. --- Automation. --- Industrial vacuum --- Vacuum --- Vacuum in industry --- Ultrahigh vacuum --- High vacuum technique --- Electric discharges through gases --- Blood Plasma --- Fresh Frozen Plasma --- Blood Plasmas --- Fresh Frozen Plasmas --- Frozen Plasma, Fresh --- Frozen Plasmas, Fresh --- Plasma, Blood --- Plasma, Fresh Frozen --- Plasmas --- Plasmas, Blood --- Plasmas, Fresh Frozen --- Serum --- Vacuums --- Industrial applications
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The book describes the properties, analytical methods and the applications of different polyvinylpyrrolidone excipients (povidone, crospovidone, copovidone etc.) for use in pharmaceutical preparations. This group of excipients is one of the most important excipients used in modern technology to produce drugs. The book is intended for all persons working in the research, development and quality control of drugs. It gives a survey of all applications in solid, liquid and semisolid dosage forms including many drug formulation examples and more than 600 references to the literature.
Povidone. --- Excipients. --- Drug emulsifying agents --- Drug formulation agents --- Drug stabilizing agents --- Drug suspending agents --- Emulsifying agents for drugs --- Suspending agents for drugs --- Drugs --- Stabilizing agents --- Ethenylpyrrolidinonehomopolymer --- Polyvidon --- Polyvinylpyrrolidone --- PVP --- Blood plasma substitutes --- Pyrrolidine --- Pharmacy. --- Polymers. --- Analytical biochemistry. --- Polymer Sciences. --- Analytical Chemistry. --- Analytic biochemistry --- Biochemistry --- Chemistry, Analytic --- Polymere --- Polymeride --- Polymers and polymerization --- Macromolecules --- Chemistry --- Medicine --- Materia medica --- Pharmacology --- Bioanalytic chemistry --- Bioanalytical chemistry --- Analytical chemistry --- Polymers . --- Analytical chemistry. --- Analysis, Chemical --- Analytic chemistry --- Chemical analysis
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Pathological haematology --- Hematology --- Hématologie --- Periodicals --- periodicals --- Périodiques --- Hematology. --- Health Sciences --- Life Sciences --- Clinical Medicine --- Diagnostics --- Diseases --- Endocrinology --- Pathology --- Cytology, Cell Biology --- Micro and Molecular Biology --- Hématologie --- Périodiques --- EBSCOASP-E EJMEDEC EPUB-ALPHA-E EPUB-PER-FT MDHEMATO WILEY-E --- Haematology --- periodicals. --- Internal medicine --- Blood --- Hematologie. --- Health. --- Health --- MDHEMATO --- Hematology - Periodicals --- body fluids --- cardiovascular system --- blood cells --- blood plasma --- arterioles --- blood donors --- blood groups --- blood transfusion --- blood viscosity --- blood volume --- fungemia --- hematology --- haematology --- medical sciences --- blood sampling --- Biological Sciences --- blood --- blood banks --- blood chemistry --- blood circulation --- blood coagulation --- blood stasis --- hematologic agents --- hematologic diseases --- hematologic tests --- hematopoiesis
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