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TECHNOLOGY & ENGINEERING --- Military Science --- Medicine, Military --- Drug interactions --- Drug utilization --- Pharmacological Processes --- Drug Information Services --- Occupational Groups --- Environmental Pollutants --- Product Surveillance, Postmarketing --- Biological Products --- Evaluation Studies as Topic --- Complex Mixtures --- Persons --- Pharmacological Phenomena --- Toxic Actions --- Information Services --- Pharmaceutical Services --- Physiological Processes --- Health Services --- Chemicals and Drugs --- Chemical Actions and Uses --- Investigative Techniques --- Physiological Phenomena --- Information Science --- Named Groups --- Phenomena and Processes --- Health Care Facilities, Manpower, and Services --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Health Care --- Adverse Drug Reaction Reporting Systems --- Drug Interactions --- Military Personnel --- Hazardous Substances --- Vaccines --- Medicine --- Health & Biological Sciences --- Military & Naval Medicine --- Evaluation --- Drug interactions. --- Evaluation. --- Interactions, Drug --- Drugs --- Side effects
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Drug-Related Side Effects and Adverse Reactions. --- Environmental Pollutants. --- Food Additives --- toxicity. --- Pollutants, Environmental --- Adverse Drug Event --- Adverse Drug Reaction --- Drug Side Effects --- Drug Toxicity --- Side Effects of Drugs --- Toxicity, Drug --- Adverse Drug Events --- Adverse Drug Reactions --- Drug Event, Adverse --- Drug Events, Adverse --- Drug Reaction, Adverse --- Drug Reactions, Adverse --- Drug Related Side Effects and Adverse Reactions --- Drug Side Effect --- Drug Toxicities --- Effects, Drug Side --- Reactions, Adverse Drug --- Side Effect, Drug --- Side Effects, Drug --- Toxicities, Drug --- Drug Therapy --- Pharmaceutical Preparations --- adverse effects --- toxicity --- Radiation Exposure --- Environmental Exposure --- Environmental Pollution --- Contraindications, Drug --- Drug Interactions --- Clinical Trials, Phase IV as Topic --- Pollutants --- Environmental Pollutant --- Pollutant --- Pollutant, Environmental
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This book focuses of the neurotransmission phenomenon. By definition, neurotransmitters are chemicals that enable communication, i.e., the flow of nerve impulses between nerve cells or between nerve cells and muscles and glands. Recently, one can distinguish excitatory and inhibitory mediators, both of which are endo–exogenous compounds that control the function of the whole organism. From a chemical point of view, neurotransmitters belong to many different structural groups, such as amino acids (such as glycine), peptides (such as substance P, somatostatin), monoamines (such as noradrenaline or dopamine), purine derivatives (such as adenosine), gases (such as nitrogen, NO, carbon monoxide CO), and acetylcholine. From a medical point of view, disturbances in the concentration of neurotransmitters in the body result in the occurrence of mental disorders and diseases (such as depression, schizophrenia, Parkinson’s disease) and contribute to the occurrence of dementia (including Alzheimer’s disease), among other diseases. However, the problem is much wider. These disorders can lead to a number of cardiovascular diseases and can lead to the development of vascular diseases of the brain as well as in many other organs. Therefore, pharmacological intervention is a therapy that tries to interfere with regulatory processes year after year. Such treatments improve survival, reduce the frequency of readmission, and improve patients' quality of life.
white matter hyperintensities --- dysautonomia --- genetic polymorphisms --- dementia --- levodopa --- renin-angiotensin system --- orthostatic hypotension --- reserpine-induced fibromyalgia model --- vortioxetine --- ropinirole --- serotonin and dopamine in fibromyalgia --- mouse --- dopamine --- acetylcholine --- glutamate --- BDNF --- serotonin --- neurotransmitters --- statins --- neurodegenerative diseases --- stroke --- depression --- androgenetic alopecia --- 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors --- mixed dyslipidemia --- risk factors --- halogenated pyrazolines --- monoamine oxidase inhibitors --- kinetics --- reversibility --- molecular dynamics --- guanylate cyclase (GC) --- chronic heart failure (CHF) --- pulmonary arterial hypertension (PAH) --- tiagabine --- cardiac voltage-gated ion channels --- molecular modeling --- ECG study --- SGLT2i --- sodium-glucose cotransporter 2 inhibitors --- neuroprotection --- atheroprotection --- mTOR --- type 2 diabetes mellitus --- cognitive impairment --- inflammation --- oxidative stress --- antibiotics --- neurotoxicity --- adverse drug reaction --- neurotransmission --- 5-HT receptors --- gastrointestinal tract
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Adverse drug reactions are one of the major constraints when using drugs. These adverse reactions can impact healthcare systems as strongly as many prevalent diseases. Identifying DNA variants associated with adverse drug reactions can help personalize medicine and sustain healthcare systems. This book delves into new advances in pharmacogenetics of cardiovascular, cancer, and nervous system drugs. It may be useful for clinicians and patients to understand the basics of pharmacogenetics.
5-fluorouracil --- capecitabine --- fluoropyrimidine --- thymidylate synthase --- thymidylate synthase enhancer region --- upstream stimulatory factor 1 --- adverse drug reactions --- pharmacogenomics --- epistasis --- random forest --- statin --- cardiovascular disease --- colorectal cancer --- personalised medicine --- toxicity --- (es)citalopram --- drug-gene-interaction --- drug-drug-interaction --- drug-drug-gene-interaction --- the PharmLines initiative --- antipsychotic agents --- pharmacogenetics --- cytochrome P-450 enzyme system --- psychotic disorders --- precision medicine --- direct oral anticoagulants --- clinical implementation --- atorvastatin --- SLCO1B1 --- HLA --- cutaneous adverse drug reaction --- SCAR --- genetic polymorphism --- antiepileptics --- CYP450 enzymes --- platelet reactivity --- single-nucleotide variants --- acute coronary syndrome --- clopidogrel --- genotype --- allele --- polymorphism --- HLA B --- CYP2C9*3 --- cutaneous adverse drug reactions (CADRs) --- anti-epileptic drugs (AEDS) --- phenytoin (PHT) --- genetic risk factors --- South India --- India --- cardiology --- adverse events --- guidelines --- n/a
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Pharmacology. Therapy --- Pharmacology --- Environmental toxicology --- Environmental Pollutants --- Pharmaceutical Preparations --- Pharmacologie --- Ecotoxicologie --- Periodicals --- periodicals --- toxicity --- Périodiques --- Drug Toxicity. --- Environmental Pollutants. --- Pharmacology. --- Écotoxicologie --- Périodiques. --- Toxicology. --- Evidence Based Toxicology --- Evidence-Based Toxicology --- Toxinology --- Based Toxicologies, Evidence --- Based Toxicology, Evidence --- Evidence Based Toxicologies --- Evidence-Based Toxicologies --- Toxicologies, Evidence Based --- Toxicologies, Evidence-Based --- Toxicology, Evidence Based --- Toxicology, Evidence-Based --- Pharmacogenetics --- Pharmacologies --- pharmacology --- Agriculture Sciences --- Health Sciences --- Veterinary Science --- Public health --- farmacologie --- toxicologie --- Toxicology --- Pollutants --- Pollutants, Environmental --- Environmental Pollutant --- Pollutant --- Pollutant, Environmental --- Radiation Exposure --- Environmental Exposure --- Environmental Pollution --- Adverse Drug Event --- Adverse Drug Reaction --- Drug Side Effects --- Drug Toxicity --- Side Effects of Drugs --- Toxicity, Drug --- Adverse Drug Events --- Adverse Drug Reactions --- Drug Event, Adverse --- Drug Events, Adverse --- Drug Reaction, Adverse --- Drug Reactions, Adverse --- Drug Related Side Effects and Adverse Reactions --- Drug Side Effect --- Drug Toxicities --- Effects, Drug Side --- Reactions, Adverse Drug --- Side Effect, Drug --- Side Effects, Drug --- Toxicities, Drug --- Drug Therapy --- Contraindications, Drug --- Drug Interactions --- Clinical Trials, Phase IV as Topic --- adverse effects
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Health Sciences --- Pharmacy and Pharmacology --- Therapeutics --- Internal medicine --- Internal medicine. --- Drug-Related Side Effects and Adverse Reactions. --- Drug Therapy. --- Medicine, Internal --- Medicine --- Therapy, Drug --- Chemotherapy --- Pharmacotherapy --- Chemotherapies --- Drug Therapies --- Pharmacotherapies --- Therapies, Drug --- Disease --- Pharmaceutical Preparations --- Pharmacologic Actions --- Adverse Drug Event --- Adverse Drug Reaction --- Drug Side Effects --- Drug Toxicity --- Side Effects of Drugs --- Toxicity, Drug --- Adverse Drug Events --- Adverse Drug Reactions --- Drug Event, Adverse --- Drug Events, Adverse --- Drug Reaction, Adverse --- Drug Reactions, Adverse --- Drug Related Side Effects and Adverse Reactions --- Drug Side Effect --- Drug Toxicities --- Effects, Drug Side --- Reactions, Adverse Drug --- Side Effect, Drug --- Side Effects, Drug --- Toxicities, Drug --- Drug Therapy --- Contraindications, Drug --- Drug Interactions --- Clinical Trials, Phase IV as Topic --- drug therapy --- therapeutic use --- adverse effects --- toxicity --- Internal Medicine
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Written by international authorities in ocular toxicology, including the Founder of The National Registry of Drug-Induced Side Effects and its current Director, this essential resource provides the clinically relevant information you need to effectively diagnose and manage herbal, chemical, and drug-related ocular problems. Comprehensive coverage of all drugs' generic and trade drug names, primary uses, ocular and systemic side effects, and clinical significance make this book - like its best-selling predecessor, Drug-Induced Ocular Side Effects - the ideal reference for quick, on-the-spot con
Clinical toxicology --- Ocular pharmacology --- Ocular toxicology --- Ocular toxicity --- Oculotoxicity --- Oculotoxicology --- Toxicology --- Eye --- Ophthalmopharmacology --- Pharmacology --- Ophthalmic drugs --- Clinical medicine --- Drug effects --- Effect of drugs on --- Eye Diseases --- Drug-Related Side Effects and Adverse Reactions. --- Adverse Drug Event --- Adverse Drug Reaction --- Drug Side Effects --- Drug Toxicity --- Side Effects of Drugs --- Toxicity, Drug --- Adverse Drug Events --- Adverse Drug Reactions --- Drug Event, Adverse --- Drug Events, Adverse --- Drug Reaction, Adverse --- Drug Reactions, Adverse --- Drug Related Side Effects and Adverse Reactions --- Drug Side Effect --- Drug Toxicities --- Effects, Drug Side --- Reactions, Adverse Drug --- Side Effect, Drug --- Side Effects, Drug --- Toxicities, Drug --- Drug Therapy --- Pharmaceutical Preparations --- Contraindications, Drug --- Drug Interactions --- Clinical Trials, Phase IV as Topic --- drug effects. --- chemically induced. --- methods. --- adverse effects --- toxicity --- Drug-Related Side Effects and Adverse Reactions --- drug effects --- chemically induced --- methods
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Pharmacoepidemiology --- Drugs --- Pharmaceutical Preparations --- Toxicology. --- Pharmacoepidemiology. --- Side effects --- Toxicology --- adverse effects. --- Side effects. --- Medicaments --- Medications --- Medicine (Drugs) --- Medicines (Drugs) --- Pharmaceuticals --- Prescription drugs --- Epidemiology --- Bioactive compounds --- Medical supplies --- Pharmacopoeias --- Chemotherapy --- Materia medica --- Pharmacology --- Pharmacy --- Drug toxicity --- Adverse drug reactions --- Adverse reactions to drug therapy --- Drug-induced disease --- Drug side effects --- Side effects of drugs --- Iatrogenic diseases --- Drug interactions --- Evidence Based Toxicology --- Evidence-Based Toxicology --- Toxinology --- Based Toxicologies, Evidence --- Based Toxicology, Evidence --- Evidence Based Toxicologies --- Evidence-Based Toxicologies --- Toxicologies, Evidence Based --- Toxicologies, Evidence-Based --- Toxicology, Evidence Based --- Toxicology, Evidence-Based --- Pharmacogenetics --- Complications --- Adverse reactions --- Physiological effect --- Health Sciences --- Pharmacy and Pharmacology --- Drug-Related Side Effects and Adverse Reactions. --- Adverse Drug Event --- Adverse Drug Reaction --- Drug Side Effects --- Drug Toxicity --- Side Effects of Drugs --- Toxicity, Drug --- Adverse Drug Events --- Adverse Drug Reactions --- Drug Event, Adverse --- Drug Events, Adverse --- Drug Reaction, Adverse --- Drug Reactions, Adverse --- Drug Related Side Effects and Adverse Reactions --- Drug Side Effect --- Drug Toxicities --- Effects, Drug Side --- Reactions, Adverse Drug --- Side Effect, Drug --- Side Effects, Drug --- Toxicities, Drug --- Drug Therapy --- Contraindications, Drug --- Drug Interactions --- Clinical Trials, Phase IV as Topic --- adverse effects --- toxicity --- drug safety --- clinical toxicology --- pharmacology --- pharmacotherapeutics --- Pharmacology. Therapy
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Ocular toxicology --- Ocular pharmacology --- Drugs --- Eye Diseases --- Eye --- Drug-Related Side Effects and Adverse Reactions. --- Toxicology --- Side effects --- chemically induced. --- drug effects. --- methods. --- Ocular toxicology. --- Ocular pharmacology. --- Side effects. --- Adverse drug reactions --- Adverse reactions to drug therapy --- Chemotherapy --- Drug-induced disease --- Drug side effects --- Side effects of drugs --- Iatrogenic diseases --- Drug interactions --- Ophthalmopharmacology --- Pharmacology --- Ophthalmic drugs --- Ocular toxicity --- Oculotoxicity --- Oculotoxicology --- Complications --- Adverse reactions --- Physiological effect --- Drug effects --- Effect of drugs on --- Drug Interactions. --- Iatrogenic Disease. --- Hospital-Acquired Condition --- Condition, Hospital-Acquired --- Conditions, Hospital-Acquired --- Disease, Iatrogenic --- Diseases, Iatrogenic --- Hospital Acquired Condition --- Hospital-Acquired Conditions --- Iatrogenic Diseases --- Medical Errors --- Drug Interaction --- Interaction, Drug --- Interactions, Drug --- Contraindications, Drug --- Metabolic Detoxication, Phase I --- Drug-Related Side Effects and Adverse Reactions --- Metabolic Side Effects of Drugs and Substances --- Adverse Drug Event --- Adverse Drug Reaction --- Drug Side Effects --- Drug Toxicity --- Side Effects of Drugs --- Toxicity, Drug --- Adverse Drug Events --- Adverse Drug Reactions --- Drug Event, Adverse --- Drug Events, Adverse --- Drug Reaction, Adverse --- Drug Reactions, Adverse --- Drug Related Side Effects and Adverse Reactions --- Drug Side Effect --- Drug Toxicities --- Effects, Drug Side --- Reactions, Adverse Drug --- Side Effect, Drug --- Side Effects, Drug --- Toxicities, Drug --- Drug Therapy --- Pharmaceutical Preparations --- Drug Interactions --- Clinical Trials, Phase IV as Topic --- adverse effects --- toxicity --- Iatrogenic Disease --- chemically induced --- drug effects --- methods
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Pharmacology. --- Drug Evaluation, Preclinical. --- Drug-Related Side Effects and Adverse Reactions. --- Drug Evaluation. --- Consumer Product Safety. --- Risk Management. --- Hospital Incident Reportings --- Incident Reporting --- Incident Reportings, Hospital --- Management, Risks --- Reporting, Hospital Incident --- Reportings, Hospital Risk --- Voluntary Patient Safety Event Reporting --- Hospital Incident Reporting --- Incident Reporting, Hospital --- Hospital Risk Reporting --- Hospital Risk Reportings --- Incident Reportings --- Management, Risk --- Reporting, Hospital Risk --- Reporting, Incident --- Reportings, Hospital Incident --- Reportings, Incident --- Risk Reporting, Hospital --- Risk Reportings, Hospital --- Risks Management --- Truth Disclosure --- Product Approval --- Safety, Consumer Product --- Product Approvals --- Product Safety, Consumer --- Drug Evaluation Studies --- Evaluation Studies, Drug --- Drug Evaluation Study --- Drug Evaluations --- Evaluation Study, Drug --- Evaluation, Drug --- Evaluations, Drug --- Studies, Drug Evaluation --- Study, Drug Evaluation --- Drugs, Investigational --- Adverse Drug Event --- Adverse Drug Reaction --- Drug Side Effects --- Drug Toxicity --- Side Effects of Drugs --- Toxicity, Drug --- Adverse Drug Events --- Adverse Drug Reactions --- Drug Event, Adverse --- Drug Events, Adverse --- Drug Reaction, Adverse --- Drug Reactions, Adverse --- Drug Related Side Effects and Adverse Reactions --- Drug Side Effect --- Drug Toxicities --- Effects, Drug Side --- Reactions, Adverse Drug --- Side Effect, Drug --- Side Effects, Drug --- Toxicities, Drug --- Drug Therapy --- Pharmaceutical Preparations --- Contraindications, Drug --- Drug Interactions --- Clinical Trials, Phase IV as Topic --- Drug Evaluation Studies, Preclinical --- Drug Evaluations, Preclinical --- Evaluation Studies, Drug, Preclinical --- Evaluation, Preclinical Drug --- Evaluations, Preclinical Drug --- Medicinal Plants Testing, Preclinical --- Preclinical Drug Evaluation --- Preclinical Drug Evaluations --- Drug Screening --- Evaluation Studies, Drug, Pre-Clinical --- Drug Screenings --- Screening, Drug --- Screenings, Drug --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemicals --- Chemotherapy --- Drugs --- Pharmacy --- adverse effects --- toxicity --- Physiological effect
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