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Carcinogens. --- Neoplasms --- chemically induced.
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Protein phosphorylation reactions are carried out in a cell by protein kinases, which predominantly use ATP as a phosphate donor that is transferred and covalently bound to an amino acid on a substrate protein. Protein phosphorylation was discovered in 1954 by Edmond Fischer who shared the Nobel Prize in Medicine or Physiology in 1992 with Edwin Krebs. There are so many kinases that one was called ""Just Another Kinase"" for JAK kinase. Their counterpart is protein phosphatases that remove phosphates from phosphorylated proteins. Kinases and phosphatases act as switches in the cell that activates or inactivates protein functions. These reactions are reversible; the cell can quickly react to a situation but can then go back to its initial state.
Chemical carcinogenesis. --- Chemical induction of cancer --- Chemical induction of neoplasms --- Chemical induction of tumors --- Chemical tumorigenesis --- Chemically induced cancer --- Chemically induced neoplasm --- Chemically induced neoplasms --- Chemically induced tumor --- Chemically induced tumors --- Carcinogenesis --- Life Sciences --- Genetics and Molecular Biology --- Chemical Biology --- Biochemistry --- Bioorganic Chemistry
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This book provides an overview on the molecular mode of action of carcinogenic polycyclic aromatic hydrocarbons (PAHs). PAHs are by-products arising from incomplete combustion of organic matter that are frequently released into our environment, and thus are ubiquitously detectable. Many PAHs are strong carcinogens in rodent bioassays and have been linked to increased incidences of various types of cancer in humans. The present book covers all aspects of PAH-induced carcinogenesis; it is a collection of articles written by some of the most recognizable PAH researchers, reviewing the present kno
Chemical carcinogenesis. --- Genetic toxicology. --- Polycyclic aromatic hydrocarbons --- Benzenoid hydrocarbons --- PAHs (Chemicals) --- Polyarenes --- Polynuclear aromatic hydrocarbons --- Hydrocarbons --- Polycyclic aromatic compounds --- Genotoxicity --- Genotoxicology --- Toxicology --- Biochemical genetics --- Medical genetics --- Carcinogenesis --- Chemical mutagenesis --- Chemical induction of cancer --- Chemical induction of neoplasms --- Chemical induction of tumors --- Chemical tumorigenesis --- Chemically induced cancer --- Chemically induced neoplasm --- Chemically induced neoplasms --- Chemically induced tumor --- Chemically induced tumors --- Carcinogenicity. --- Toxicology. --- Genetic aspects
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Nephrology. --- Kidneys --- Kidney Diseases --- Kidney Neoplasms --- Nephrology --- Cancer. --- Tumors. --- therapy. --- chemically induced. --- methods. --- Rein --- Cancérologie --- therapy --- Maladies --- Thérapeutique. --- chemically induced --- methods
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The Understanding, Prevention and Control of Human Cancer is an account of how a married couple opened understanding of environmental carcinogenesis. Elizabeth Cavert and James A. Miller showed that enzymes of the human body activate and enable otherwise benign organic chemicals to combine with DNA in such a manner that cancer results. Their work is of particular note because cancer causes more loss of life-years than the sum of all other causes of death—and, as the President’s (USA) Cancer Panel warned, environmental carcinogenesis is a form of cancer that has been previously “grossly underestimated”. The Millers’ cancer research led to tests that identify dangerous chemicals which in turn permits prevention and thus the control of human cancer.
Oncologists --- Cancer --- Chemical carcinogenesis --- Environmentally induced diseases --- Cancers --- Carcinoma --- Malignancy (Cancer) --- Malignant tumors --- Tumors --- Clinical ecology --- Diseases --- Environmental illness --- Environmental health --- Medical geography --- Chemical induction of cancer --- Chemical induction of neoplasms --- Chemical induction of tumors --- Chemical tumorigenesis --- Chemically induced cancer --- Chemically induced neoplasm --- Chemically induced neoplasms --- Chemically induced tumor --- Chemically induced tumors --- Carcinogenesis --- Cancer specialists --- Cancerologists --- Medical scientists --- Physicians --- Research --- History --- Prevention --- Environmental aspects --- Causes and theories of causation --- Miller, Elizabeth C. --- Miller, James A.
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Drugs for Pregnant and Lactating Women, 2nd Edition, by Carl P. Weiner, MD, MBA, FACOG, and Catalin Buhimschi, MD, is a must-have reference that details how virtually all of today's drugs and herbal supplements interact with pregnancy and lactation. Updated thoroughly and covering nearly 2,000 substances, the new edition explains whether each drug is FDA-approved for use by expecting or nursing mothers...is known to be safe for use...or is known to pose a danger. An alphabetical organization by both trade and generic name...a special index listing drugs by category...and an easy-to-read page f
Fetus --- Newborn infants --- Obstetrical pharmacology --- Effect of drugs on --- Breast Feeding --- Infant. --- Pharmaceutical Preparations --- Pregnancy Complications --- Pregnancy --- adverse effects --- drug effects --- contraindications --- chemically induced
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"Ideal for ophthalmologists, optometrists and busy clinicians, Drug-Induced Ocular Side Effects provides the clinically relevant information you need to diagnose and manage chemical and drug-related ocular problems. An easily accessible format, meticulous revisions and comprehensive coverage of all drugs' generic and trade names, primary uses, ocular and systemic side effects, and clinical significance make this best-selling resource the ideal reference for quick, on-the-spot consultation"--Publisher's description.
Eye Diseases --- Eye --- Drug-Related Side Effects and Adverse Reactions --- Toxicology --- Oeil --- Médicaments --- Toxicologie. --- chemically induced --- drug effects --- methods --- Maladies. --- Effets secondaires. --- Ocular pharmacology --- Drugs --- Ocular toxicology --- Eye Disorders --- Eye Disease --- Eye Disorder --- Ophthalmology --- Ocular toxicity --- Oculotoxicity --- Oculotoxicology --- Ophthalmopharmacology --- Pharmacology --- Ophthalmic drugs --- Side effects --- Drug effects --- Effect of drugs on --- Drug-Related Side Effects and Adverse Reactions. --- chemically induced. --- drug effects. --- methods.
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"Clinical Signs in Humans and Animals Associated with Minerals, Trace Elements and Rare Earth Elements is the first book to compile the clinical signs associated with deficiencies, toxicities, imbalances, exposures to minerals, trace elements and rare earth elements in animals. This book aims to increase awareness to improve diagnosis and to encourage further investigation based on comparative data. Written by an experienced veterinary clinician having worked in private practice, academia, pharmaceutical and pet food industries, this book includes data on companion animals, horses, rabbits, reptiles, ruminants, poultry, fish, and species typical in zoo populations. In addition, the book touches upon human and other primate data. The subject material is divided into three sections to provide easy access to information on clinical signs, specific elements, or species. This is an ideal resource for veterinary researchers, clinicians and practitioners, specifically those working with animal nutrition and animal feed health. Academics and public health scientists will also benefit from this book's information and data on rehabilitating and maintaining animal health"-- |c Provided by publisher.
Minerals in animal nutrition. --- Feeds --- Animal nutrition --- Mineral content --- Trace Elements --- Metals, Heavy --- Phosphorus --- Transition Elements --- Metalloids --- Elements --- Occupational Exposure --- Chemically-Induced Disorders --- Poisoning --- Animals --- Humans --- Oligoéléments. --- Éléments (chimie) --- Métaux. --- Intoxication. --- Risques professionnels --- Chez les animaux --- Trace Elements. --- Occupational Exposure. --- Poisoning. --- Animals. --- Humans. --- Metals, Heavy. --- Phosphorus. --- Transition Elements. --- Metalloids. --- Elements. --- Chemically-Induced Disorders.
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Environmental pollutants such as lead, mercury, and pesticides interfere with brain development, yet we do not test industrial chemicals for brain toxicity. In this book, Philippe Grandjean argues for the necessity of protecting the brains of future generations and proposes a plan of action to halt what he refers to as chemical brain drain.
Brain --- Brain Diseases --- Environmental Pollution --- Prenatal influences. --- Fetus --- Pollution. --- Influence prénatale --- Foetus --- Cerveau --- Pollution --- growth & development. --- chemically induced. --- prevention & control. --- adverse effects. --- Abnormalities --- Etiology --- Diseases --- Environmental aspects --- Malformations --- Maladies --- Aspect de l'environnement --- Children --- Pregnancy --- Etiology.
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Neurotoxicology --- Behavioral toxicology --- Nervous system --- Neuropsychological tests --- Diseases --- Behavior and Behavior Mechanisms --- Noxae --- Publication Formats --- Psychiatry and Psychology --- Publication Characteristics --- Toxic Actions --- Chemical Actions and Uses --- Chemicals and Drugs --- Nervous System Diseases --- Neurotoxins --- Behavior --- Congresses --- Medicine --- Health & Biological Sciences --- Neurology --- Environmental aspects --- drug effects --- chemically induced --- adverse effects --- Environmental toxicology --- Drug effects --- Chemically induced --- Adverse effects --- Neuropsychological assessment --- Neuropsychological evaluation --- Tests, Neuropsychological --- Organs (Anatomy) --- Neurosciences --- Clinical neuropsychology --- Neurologic examination --- Psychological tests
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