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This collection of specially commissioned articles aims to shed light on the Early Modern printer's mark, a very productive Early Modern word-image so far only occasionally noted outside the domain of book history. It does so from the perspectives of book history, literary history, especially emblem scholarship, and art history. The various contributions to the volume address issues such as those of the adoption of printer's devices in the place of the older heraldic printer's marks as a symptom of the changing self-image of the representatives of the Early Modern printing profession, of the mutual influence of emblems and printer's marks, of the place of Classical learning in the design of Humanist printer's marks, of the economic factors involved in the evolution of Early Modern printer's marks, the pictorial topics of the Early Modern printer's mark, and the printer's mark as a result of the 'Verbürgerlichung' of the device of Early Modern nobility. Special care was taken to account for the similarities and differences of the printer's marks produced and used in different regional and cultural contexts. The printer's mark thus becomes visible as a European phenomenon that invites studying some of the most significant shared aspects of Early Modern culture.
Marques typographiques --- printer's marks --- Book history --- Graphics industry --- Marques typographiques. --- Printers' marks --- History --- Printers. --- Printers --- History. --- Printers' marks - History
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Bibliotheques --- Qualite --- Controle --- libraries --- Qualité --- Quality --- Politique de marché --- Marketing policies --- Normalisation --- Standardizing --- Modèle --- Models --- Consumer behaviour --- Pays développé --- Developed countries --- 025 Bibliotheekbeheer --- 025 --- Bibliotheekbeheer --- Libraries --- Library education --- Documentation --- Public institutions --- Librarians --- Marketing --- Quality control --- Applied marketing --- Library management --- Normes --- Information retrieval --- Gestion --- management --- case studies --- Éducation --- education --- Developing countries --- Public relations --- Relations publiques --- Study and teaching --- Congresses --- Case studies --- Etude et enseignement --- Congrès --- Bibliothèques --- Cas, Etudes de --- Management --- International Federation of Library Associations and Institutions --- management. --- education. --- Bibliothèques. --- Contrôle --- Libraries - Marketing - Congresses. --- Libraries - Quality control - Congresses. --- Library education - Congresses. --- Bibliotheques - Marketing - Congres. --- Bibliotheques - Normes - Congres. --- Bibliotheques - Qualite - Controle - Congres. --- Marketing - Congres. --- Bibliothèques. --- Qualité --- Contrôle
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This book provides a 2012 reference for state-of-the-art gene transfer technology and the different aspects of its clinical translation with a focus on European-based initiatives. As examples of successful outcomes, recent clinical trials are presented together with Ethical, Safety and Regulatory issues, which are discussed. The broad range of various technologies is covered whether addressing direct in vivo gene transfer like with AAV, Adeno or non-viral vectors or ex-vivo genetically engineered cells including induced pluripotent stem cells (iPS) with integrating vectors such as retrovirus, lentivirus or transposon-derived systems. The critical path to clinical implementation is covered in the second part describing currently available tools - such as molecular imaging, ex-vivo organ cultures and high-throughput technologies used for evaluation of criteria towards a go-or-no go decision to move to the clinic; in addition, utmost salient biosafety and immunotoxicology aspects are discussed. This book is ideal for postgraduates, undergraduates, scientists, clinicians, regulators and patients' advocacy groups looking for states-of-the-art information as well as emerging prospects - including gene targeting and homologous recombination - in gene transfer intended for clinical translation.
Genetic transformation. --- Gene transfer --- Transformation (Genetics) --- Genetic recombination --- Microbial genetics --- Nucleic acids --- Transfection --- Gene Transfer Techniques --- Gene Delivery Systems --- Gene Transfer Technique --- Transgenesis --- Delivery System, Gene --- Delivery Systems, Gene --- Gene Delivery System --- Technique, Gene Transfer --- Techniques, Gene Transfer --- Transfer Technique, Gene --- Transfer Techniques, Gene --- Genetic Therapy --- Transgenes --- Human genetics --- Biotechnology
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