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Developments over the past few years have revealed the remarkable versatility of RNA in any compartment of the cell, tasks that had been thought to be exclusively in the realm of proteins and even beyond. The chapters in this book written by leading investigators in the field provide insight into various promising avenues where RNA and nucleic acid derivatives including antisense RNAs, such as siRNA, miRNAs, amplification/selection (SELEX) generated aptamers as well as ribozymes are at the threshold of impacting medicine.

RNA. --- Messenger RNA. --- Informational RNA --- Messenger ribonucleic acid --- mRNA --- Protein transcript --- Protein transcripts --- Template RNA --- RNA --- Ribonucleic acid --- Ribose nucleic acid --- Nucleic acids --- Ribose --- Biochemistry. --- Toxicology. --- Medicine. --- Biochemistry, general. --- Pharmacology/Toxicology. --- Molecular Medicine. --- Medicine/Public Health, general. --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Chemicals --- Medicine --- Pharmacology --- Poisoning --- Poisons --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Toxicology --- Composition --- Health Workforce --- Pharmacology. --- Molecular biology. --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Drug effects --- Medical pharmacology --- Chemotherapy --- Drugs --- Pharmacy --- Physiological effect --- Medical sciences. --- Biomedical Research. --- Health Sciences. --- Research. --- Basic medical sciences --- Basic sciences, Medical --- Biomedical sciences --- Health sciences --- Preclinical sciences --- Sciences, Medical --- Biological research --- Biomedical research

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In the past few years nucleic acids technologies have grown into a powerful analytical and also increasingly therapeutic tool. It has been applied not only to the uncovering of gene functions in many organisms, but also to pathogenetic analysis and recently also for the treatment of human diseases. The book discusses in depth the potential of these innovative methods in the broad field of central nervous system and brain tumours particularly. Whereas there is currently no comprehensive overview on potential and challenges of nucleic acids technologies for basic brain tumours and for the clinical management of patients with brain tumours, this book does explicitly cover the many other aspects of the "RNA World" (pathogenic and therapeutic potential of microRNAs, aptamer technology, etc.), too. With this significantly broadened scope as compared to currently existing books it appears to be an urgently needed new publication.

Brain -- Cancer. --- Brain -- Tumors. --- Brain --- RNA --- Gene Therapy --- Brain Neoplasms --- RNA, Antisense --- Glioma --- Central Nervous System Neoplasms --- Antisense Elements (Genetics) --- Neoplasms, Neuroepithelial --- Biological Therapy --- Brain Diseases --- Neuroectodermal Tumors --- Nucleic Acids --- Nucleic Acid Probes --- Nucleic Acids, Nucleotides, and Nucleosides --- Nervous System Neoplasms --- Neoplasms, Glandular and Epithelial --- Therapeutics --- Central Nervous System Diseases --- Neoplasms by Site --- Neoplasms by Histologic Type --- Nervous System Diseases --- Molecular Probes --- Chemicals and Drugs --- Neoplasms, Germ Cell and Embryonal --- Neoplasms, Nerve Tissue --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Diseases --- Neoplasms --- Laboratory Chemicals --- Specialty Uses of Chemicals --- Chemical Actions and Uses --- Oncology --- Medicine --- Health & Biological Sciences --- Gene therapy --- Cancer --- Therapeutic use --- RNA. --- Tumors. --- Ribonucleic acid --- Ribose nucleic acid --- Medicine. --- Cancer research. --- Human physiology. --- Molecular biology. --- Oncology. --- Medical biochemistry. --- Neurosurgery. --- Biomedicine. --- Cancer Research. --- Human Physiology. --- Molecular Medicine. --- Medical Biochemistry. --- Nucleic acids --- Ribose --- Oncology  . --- Biochemistry. --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Nerves --- Neurosurgery --- Physiology --- Human body --- Tumors --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Surgery --- Composition --- Health Workforce --- Medical biochemistry --- Pathobiochemistry --- Pathological biochemistry --- Biochemistry --- Molecular biochemistry --- Molecular biophysics --- Biophysics --- Biomolecules --- Systems biology --- Cancer research --- Cancer. --- Nervous system --- Clinical biochemistry. --- Cancer Biology. --- Biomedical Research. --- Surgery. --- Research. --- Cancers --- Carcinoma --- Malignancy (Cancer) --- Malignant tumors --- Biological research --- Biomedical research