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Bones --- Metabolism --- Disorders. --- Metabolic bone disease
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Many heterogeneous causes (e.g., metabolic, inflammatory, autoimmune, vascular, and renal diseases, and even drugs), collectively grouped as secondary causes of osteoporosis, may lead to bone loss or damage to architecture through a number of mechanisms. Although these secondary causes of osteoporosis are the most frequently observed causes of unexpected bone loss, they can only be diagnosed via a high degree of suspicion and clinical experience and by performing the appropriate investigations. In inflammatory disorders such as rheumatoid arthritis or chronic inflammatory bowel diseases, as well as vascular diseases, T-cell activation, and consequently pro-inflammatory cascades, trigger the increased expression of T-cell-derived RANKL. In addition, a new biomarker signature of bone-related miRNAs is promising in certain clinical features. Glucocorticoids, often used to control disease activity, decrease the number and function of osteoblasts and inhibit OPG expression. The ubiquitous occurrence of disease-related secondary changes in bone metabolism implies that numerous medical disciplines need to interact. Screening for secondary causes of osteoporosis and the search for new modes of action should present a substantial aspect of osteoporosis manageme.
Bones --- Osteoporosis --- Metabolism --- Disorders. --- Genetic aspects. --- Metabolic bone disease --- Vitamin D deficiency --- Diseases
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Metabolic Bone Disease, Third Edition is the new, expanded edition of the classic text, featuring the latest advancements and research information in this fast-moving field. The Third Edition includes the most up-to-date information on molecular mechanisms, basic biology, pathophysiology, and diagnosis and management strategies of metabolic bone disease.Key Features* Edited by ""fathers of the field""* An expanded version of a classic AP text* Complete coverage of a fast-growing field
Bone Diseases --- Metabolic Diseases --- Bone and Bones --- metabolism --- Bones --- Metabolic bone disease --- Metabolism --- Disorders. --- Diseases. --- Bone and Bones - metabolism
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Os --- Minéraux --- Tissu osseux --- Bone Diseases, Metabolic. --- Minerals --- Bone and Bones --- Maladies --- Métabolisme --- metabolism --- Bones --- Mineral metabolism --- Mineral metabolism disorders --- Metabolic bone disease --- Metabolism --- Disorders --- metabolism. --- Maladies. --- Métabolisme.
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The Bioarchaeology of Metabolic Bone Disease provides a comprehensive and invaluable source of information on this important group of diseases. It is an essential guide for those engaged in either basic recording or in-depth research on human remains from archaeological sites. The range of potential tools for investigating metabolic diseases of bone are far greater than for many other conditions, and building on clinical investigations, this book will consider gross, surface features visible using microscopic examination, histological and radiological features of bone, that can be use
Bones --- Human remains (Archaeology) --- Paleopathology. --- Metabolism --- Disorders. --- Medical archaeology --- Pathology --- Bioarchaeology --- Skeletal remains (Archaeology) --- Human skeleton --- Primate remains (Archaeology) --- Metabolic bone disease
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Bones --- Mineral metabolism --- Bone and Bones --- Bone Diseases, Metabolic --- Minerals --- Metabolic Bone Diseases --- Low Bone Density --- Low Bone Mineral Density --- Osteopenia --- Bone Density, Low --- Bone Disease, Metabolic --- Low Bone Densities --- Metabolic Bone Disease --- Osteopenias --- Mineral metabolism disorders --- Osteology --- Musculoskeletal system --- Bone --- Skeleton --- Diseases --- Metabolism&delete& --- Disorders --- metabolism --- Metabolism --- Metabolic bone disease --- Bone diseases, Metabolic --- Bone and bones
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Bone Diseases, Metabolic. --- Bone and Bones --- metabolism. --- Metabolic Bone Diseases --- Osteopenia --- Bone Disease, Metabolic --- Disease, Metabolic Bone --- Diseases, Metabolic Bone --- Metabolic Bone Disease --- Osteopenias --- Low Bone Density --- Low Bone Mineral Density --- Bone Density, Low --- Low Bone Densities --- Bones --- Metabolism
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Bones --- Mineral metabolism --- Metabolism --- Disorders --- Diseases --- Osteology --- Mineral metabolism. --- Diseases. --- Metabolism. --- Disorders. --- Musculoskeletal system --- Bone --- Skeleton --- Minerals in nutrition --- Minerals in the body --- Metabolic bone disease --- Musculoskeletal System Diseases
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This concise, case-based text discusses the current state of the art for the diagnosis and management of metabolic bones diseases. Each chapter opens with a unique case presentation and utilizes a consistent format that includes relevant anatomy, physiology, and pathophysiology as well as examination, treatment approaches and clinical outcomes. Topics covered include osteoporosis, rickets and osteomalacia, hypoparathyroidism and pseudohypoparathyroidism, osteogenesis imperfecta, Paget's disease of bone, calcium and phosphorous disorders, hypophosphatasia, sclerotic bone disorders, fibrous and osteochondroplasia, and other malignancies of bone. Written and edited by experts in the field, Metabolic Bone Diseases is a valuable resource for practicing endocrinologists, rheumatologists and orthopedic surgeons, residents and fellows.
Bones --- Metabolism --- Disorders. --- Metabolic bone disease --- Endocrinology. --- Metabolic diseases. --- Orthopedics. --- Metabolic Diseases. --- Orthopaedics --- Orthopedia --- Surgery --- Disorders of metabolism --- Metabolic diseases --- Metabolic disorders --- Metabolism, Disorders of --- Diseases --- Internal medicine --- Hormones --- Endocrinology .
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Bones --- Mineral metabolism --- Bone Diseases, Metabolic. --- Bone and Bones --- Calcium Metabolism Disorders. --- Minerals --- Mineral metabolism. --- Metabolism --- Disorders --- Diseases --- metabolism. --- Diseases. --- Metabolism. --- Disorders. --- Calcium Metabolism Disorder --- Disorder, Calcium Metabolism --- Disorders, Calcium Metabolism --- Metabolic Bone Diseases --- Osteopenia --- Bone Disease, Metabolic --- Disease, Metabolic Bone --- Diseases, Metabolic Bone --- Metabolic Bone Disease --- Osteopenias --- Metabolic bone disease --- Osteology --- Bone Diseases, Metabolic --- Calcium Metabolism Disorders --- metabolism --- Bone --- Bones and Bone --- Bones and Bone Tissue --- Bony Apophyses --- Bony Apophysis --- Condyle --- Bone Tissue --- Apophyses, Bony --- Apophysis, Bony --- Bone Tissues --- Condyles --- Tissue, Bone --- Tissues, Bone --- Skeleton --- Minerals in nutrition --- Minerals in the body --- Musculoskeletal system --- Low Bone Density --- Low Bone Mineral Density --- Bone Density, Low --- Low Bone Densities --- Mineral
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