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Abnormalities, Drug-Induced. --- Prenatal Exposure Delayed Effects. --- Late Effects, Prenatal Exposure --- Delayed Effects, Prenatal Exposure --- Maternal Exposure --- Abnormalities, Drug-induced --- PRENATAL EXPOSURE DELAYED EFFECTS --- Abnormalities, Drug-induced. --- PRENATAL EXPOSURE DELAYED EFFECTS. --- Abnormalities, drug-induced. --- Prenatal exposure delayed effects. --- Drug-Induced Abnormalities --- Abnormalities, Drug Induced --- Abnormality, Drug-Induced --- Drug Induced Abnormalities --- Drug-Induced Abnormality --- Congenital Abnormalities --- Maternal-Fetal Exchange --- Teratogens --- Teratogenesis --- chemically induced --- Abnormalities, Drug-Induced --- Prenatal Exposure Delayed Effects
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Geneeskunde --- Médecine --- Psychologie --- Parapsychology. --- Prenatal Exposure Delayed Effects. --- Psychoanalytic Theory. --- #GSDBP --- 607.32 --- foetale ontwikkeling --- foetus --- gezondheidszorg --- psychoanalyse --- psychodynamiek --- psychologie --- Psychoanalytical Theory --- Theory, Psychoanalytic --- Oral Character --- Character, Oral --- Characters, Oral --- Oral Characters --- Psychoanalytic Theories --- Psychoanalytical Theories --- Theories, Psychoanalytic --- Theories, Psychoanalytical --- Theory, Psychoanalytical --- Late Effects, Prenatal Exposure --- Delayed Effects, Prenatal Exposure --- Maternal Exposure --- Psychic Research --- Clairvoyance --- Extrasensory Perception --- Psychical Research --- Extrasensory Perceptions --- Perception, Extrasensory --- Perceptions, Extrasensory --- Research, Psychic --- Research, Psychical --- Spirit Possession --- Telepathy --- Spiritual Therapies --- Psychoanalyse als therapie --- Parapsychology --- PRENATAL EXPOSURE DELAYED EFFECTS --- Psychoanalytic theory --- PRENATAL EXPOSURE DELAYED EFFECTS. --- Psychoanalytic theory. --- Prenatal exposure delayed effects. --- Prenatal Exposure Delayed Effects --- Psychoanalytic Theory
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Abnormalities, Drug-Induced. --- Embryonic and Fetal Development --- Mutagenicity Tests. --- Reproduction --- Teratogens --- Prenatal Exposure Delayed Effects. --- Toxicology. --- Developmental toxicology --- Reproductive toxicology --- Toxicology --- Toxicology, Developmental --- Developmental biology --- Teratogenesis --- Evidence Based Toxicology --- Evidence-Based Toxicology --- Toxinology --- Based Toxicologies, Evidence --- Based Toxicology, Evidence --- Evidence Based Toxicologies --- Evidence-Based Toxicologies --- Toxicologies, Evidence Based --- Toxicologies, Evidence-Based --- Toxicology, Evidence Based --- Toxicology, Evidence-Based --- Pharmacogenetics --- Late Effects, Prenatal Exposure --- Delayed Effects, Prenatal Exposure --- Maternal Exposure --- Tests, Genetic Toxicity --- Toxicity Tests, Genetic --- Genetic Toxicity Tests --- Genotoxicity Tests --- Mutagen Screening --- Genetic Toxicity Test --- Genotoxicity Test --- Mutagen Screenings --- Mutagenicity Test --- Screening, Mutagen --- Screenings, Mutagen --- Test, Genotoxicity --- Tests, Genotoxicity --- Toxicity Test, Genetic --- Carcinogenicity Tests --- drug effects. --- toxicity. --- Developmental toxicology. --- Reproductive toxicology. --- Abnormalities, Drug-Induced --- Mutagenicity Tests --- Prenatal Exposure Delayed Effects --- Drug-Induced Abnormalities --- Abnormalities, Drug Induced --- Abnormality, Drug-Induced --- Drug Induced Abnormalities --- Drug-Induced Abnormality --- Congenital Abnormalities --- Maternal-Fetal Exchange --- drug effects --- toxicity --- chemically induced
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Developmental biology --- Embryology, Human --- Disease susceptibility --- Prenatal influences --- Diseases --- Developmental biology. --- Disease susceptibility. --- Embryology, Human. --- Prenatal influences. --- Prenatal Exposure Delayed Effects. --- Causes and theories of causation --- Causes and theories of causation. --- Developmental Biology. --- Disease Susceptibility. --- Susceptibility, Disease --- Diathesis --- Diatheses --- Disease Susceptibilities --- Susceptibilities, Disease --- Late Effects, Prenatal Exposure --- Delayed Effects, Prenatal Exposure --- Biology, Developmental --- Human embryology --- Aetiology --- Etiology --- Disease predisposition --- Disease proneness --- Predisposition to disease --- Proneness to disease --- Susceptibility to disease --- Development (Biology) --- Human beings --- Illness --- Illnesses --- Morbidity --- Sickness --- Sicknesses --- Susceptibility --- Maternal Exposure --- Embryonic and Fetal Development --- Growth and Development --- Children --- Fetus --- Pregnancy --- Embryology --- Human biology --- Human reproduction --- Pathology --- Constitutional diseases --- Biology --- Growth --- Ontogeny --- Medicine --- Epidemiology --- Health --- Sick --- Developmental Biology --- Prenatal Exposure Delayed Effects --- Disease Susceptibility --- Auxology --- Life Sciences
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Abnormalities, Drug-Induced --- Diethylstilbestrol --- Genitalia --- Pregnancy --- Prenatal Exposure Delayed Effects --- adverse effects --- abnormalities --- drug effects --- Fetus --- Generative organs --- Late Effects, Prenatal Exposure --- Delayed Effects, Prenatal Exposure --- Maternal Exposure --- Drug-Induced Abnormalities --- Abnormalities, Drug Induced --- Abnormality, Drug-Induced --- Drug Induced Abnormalities --- Drug-Induced Abnormality --- Congenital Abnormalities --- Maternal-Fetal Exchange --- Teratogens --- Teratogenesis --- Generative tract --- Genital organs --- Genital system --- Genital tract --- Genitals --- Organa genitalia --- Reproductive organs --- Reproductive system --- Reproductive tract --- Sex organs --- Sexual organs --- Genitourinary organs --- Reproduction --- Fetal pharmacology --- Fetus, Effect of drugs on the --- Drugs --- Perinatal pharmacology --- DES (Drug) --- Estrostilben --- Stilbestrol --- Estrogen --- Toxicology --- Effect of drugs on --- Cancer --- chemically induced --- Drug effects --- Physiological effect --- Abnormalities, Drug-Induced. --- Prenatal Exposure Delayed Effects. --- adverse effects. --- abnormalities. --- drug effects.
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Personalised medicine is the next step in healthcare, especially when applied to genetically diverse diseases such as cancers. Naturally, a host of methods need to evolve alongside this, in order to allow the practice and implementation of individual treatment regimens. One of the major tasks for the development of personalised treatment of cancer is the identification and validation of a comprehensive, robust, and reliable panel of biomarkers that guide the clinicians to provide the best treatment to patients. This is indeed important with regards to radiotherapy; not only do biomarkers allow for the assessment of treatability, tumour response, and the radiosensitivity of healthy tissue of the treated patient. Furthermore, biomarkers should allow for the evaluation of the risks of developing adverse late effects as a result of radiotherapy such as second cancers and non-cancer effects, for example cardiovascular injury and cataract formation. Knowledge of all of these factors would allow for the development of a tailored radiation therapy regime. This Special Issue of the Journal of Personalised Medicine covers the topic of Radiation Response Biomarkers in the context of individualised cancer treatments, and offers an insight into some of the further evolution of radiation response biomarkers, their usefulness in guiding clinicians, and their application in radiation therapy.
carbon-ion radiotherapy --- head-and-neck tumors --- squamous cell carcinoma --- radiosensitivity --- relative biological effectiveness --- lung cancer --- radiotherapy --- radiotherapy monitoring --- radiation-induced lung injury --- RILI --- pneumonitis --- radiation-induced lung fibrosis --- RILF --- circulating biomarkers --- microRNA --- micronuclei --- uterine cervical cancer --- cGAS --- STING --- abscopal effect --- immunotherapy --- PBMCS --- micronucleus assay --- biological dosimetry --- human blood --- genotoxicity tests --- ionizing radiation --- biomarkers --- dicentric assay --- gamma H2AX foci assay --- health surveillance analyses --- clonogenic assays --- methods --- plating --- cancer --- radiation --- head and neck cancer --- exosomes --- serum --- metabolomics --- GC/MS --- biodosimetry --- chromosome aberrations --- normal tissue toxicity --- predictive tests --- normal tissue --- biomarker --- protein --- immune infiltrate --- stroma --- tumour microenvironment --- proteomics --- telomeres --- chromosomal instability --- inversions --- prostate cancer --- IMRT --- machine learning --- individual radiosensitivity --- late effects --- personalized medicine --- liquid biopsy --- circulating tumour cells --- extracellular vesicles --- microRNAs --- immune system --- inflammation --- n/a
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