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Epigenetics Traits in Mammalian Tissues. From New Technology to New Hypotheses
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Year: 2019 Publisher: Frontiers Media SA

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact


Book
In-vitro fertilization and assisted reproduction : a history
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ISBN: 1108551947 1108579019 1108589049 1108427855 1108448240 Year: 2018 Publisher: Cambridge : Cambridge University Press,

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The birth of Louise Joy Brown - the world's first baby born following in-vitro fertilization - heralded a medical revolution. Forty years later, many thousands of babies are born each year following IVF. Assisted reproduction is a global industry with a multi-billion dollar turnover. It is a complex mix of science, clinical management, bioethics, and commercial imperatives. Many of the pioneers of IVF are still with us and have a fascinating tale to tell. Here, they relate the story of the development of IVF and related technologies in a way that will prove invaluable to future generations of practitioners seeking to understand the genesis of the specialty. This is not an academic history: rather it takes an informal and anecdotal approach; informing and entertaining for generations of past, present and future medical and scientific specialists of IVF, alongside the millions of parents, who celebrated the successes of IVF treatment worldwide.


Book
Presenting the first test-tube baby : the Edwards and Steptoe lecture of 1979
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ISBN: 100921098X 1009211005 1009210998 100921103X Year: 2023 Publisher: Cambridge : Cambridge University Press,

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In January 1979, Robert Edwards and Patrick Steptoe delivered a lecture detailing the ten-year clinical and scientific research programme that led to the birth of Louise Brown, the first baby born utilising IVF. This thoroughly-researched book provides both a full annotated transcript of the lecture as well as recorded reminiscences from those who attended, detailing the contemporary understandings of the event. An essay on the lecture's historical context adds fresh insight into the biographies of Edwards and Steptoe and highlights sources from print and broadcast media that have received scant attention in earlier publications. Current and future implications of the advances in IVF since the first procedure are also explored, examining future medical and scientific possibilities as well as ethical issues that may arise.


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Making Multiple Babies : Anticipatory Regimes of Assisted Reproduction
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ISBN: 9781800738850 Year: 2022 Publisher: New York : Berghahn Books,

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"Human beings have been producing more twins, triplets, and quadruplets than ever before, due to the expansion of medically assisted conception. This book analyzes the anticipatory regimes of making multiple babies. With archival documents, participant observation, in-depth interviews, and registry data, this book traces the global and local governance of the assisted reproductive technologies (ARTs) used to tackle multiple pregnancy since the 1970s, highlighting the early promotion of single embryo transfer in Belgium and Japan and the making of the world's most lenient guidelines in Taiwan"--


Book
In Vitro Fertilization : Innovative Clinical and Laboratory Aspects
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ISBN: 9535169629 9535105035 Year: 2012 Publisher: IntechOpen

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The field of In Vitro Fertilization is a relatively new field in medicine, constantly on the move. This field is an exquisite example of the vast power in the complementary use of basic research with clinical practice and opened a new route of great basic and clinical research possibilities. The knowledge base that allowed the accomplishment of the idea of in vitro fertilization and embryo transfer has much developed since. The vast body of research pertaining to this field allowed deepening our understanding in the processes related to reproduction. In this book on in vitro fertilization we present new and interesting updated information in various aspects of this field. This work is a result of collaborative work of an international group of professionals dedicated to contribute to the advancement of our knowledge.


Book
Umwege zum eigenen Kind : ethische und rechtliche Herausforderungen an die Reproduktionsmedizin 30 Jahre nach Louise Brown
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Year: 2008 Publisher: Universitätsverlag Göttingen

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Even 30 years after the birth of the first "artificially produced baby Louise Brown in 1978, the desire for a child remains unfulfilled for many couples. Their hopes are to modern techniques of assisted reproduction. Reproductive medicine has since made enormous progress and opens up new opportunities. With these opportunities, however, are also linked new challenges, their moral and legal implications are considerable. Auch 30 Jahre nach der Geburt des ersten „Retortenbabys“ Louise Brown im Jahr 1978 bleibt für viele Paare der Wunsch nach einem eigenen Kind unerfüllt, und ihre Hoffnungen richten sich auf moderne Techniken assistierter Reproduktion. Die Reproduktionsmedizin hat seitdem immense Fortschritte gemacht und neue Chancen eröffnet. Mit diesen Chancen ist indessen zugleich eine Fülle neuer Herausforderungen verbunden, deren moralische und rechtliche Implikationen erheblich sind. Der vorliegende Band vereint Beiträge zweier Tagungen, die im Jahr 2007 vom »Forum für Ethik in der Medizin Frankfurt am Main e.V.« gemeinsam mit der »Arbeitsgruppe Reproduktionsmedizin und Embryonenschutz in der Akademie für Ethik in der Medizin« sowie vom »Zentrum für Medizinrecht« der Universität Göttingen veranstaltet wurden und welche die aktuelle Debatte um die Reproduktionsmedizin und ihre Möglichkeiten aufgreifen. Sie wenden sich den Errungenschaften und Problemen assistierter Fortpflanzung im Allgemeinen zu, widmen jedoch ihr Augenmerk speziell donogenen Techniken (Eizellspende, Samenspende, Embryospende) sowie dem Kinderwunsch in besonderen Situationen (etwa körperliche Behinderung, letale Erkrankung eines Partners, gleichgeschlechtliche Lebensgemeinschaften).


Book
Undoing motherhood : collaborative reproduction and the deinstitutionalization of US maternity
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ISBN: 1978808712 Year: 2023 Publisher: New Brunswick, NJ : Rutgers University Press,

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In 1978 the world’s first “test-tube baby” was born from in vitro fertilization (IVF), effectively ushering in a paradigm shift for infertility treatment that relied on partially disembodied human reproduction. Beyond IVF, the ability to extract, fertilize, and store reproductive cells outside of the human body has created new opportunities for family building, but also prompted new conflicts about rights to and control over reproductive cells. In collaborative forms of reproduction that build on IVF technologies, such as egg and embryo donation and gestational surrogacy, multiple women may variously contribute to conception, gestation/birth, and the legal and social responsibilities for rearing a child, creating intentionally fragmented maternities. Undoing Motherhood examines the implications of such fragmented maternities in the post-IVF reproductive era for generating maternity uncertainty—an increasing cultural ambiguity about what does and should constitute maternity. Undoing Motherhood explores this uncertainty in the social worlds of reproductive medicine and law.


Book
Human in vitro fertilization : a case study in the regulation of medical innovation
Authors: ---
ISBN: 1855213478 9781855213470 Year: 1993 Publisher: Aldershot Dartmouth


Book
Organization and Management of IVF Units : A Practical Guide for the Clinician
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ISBN: 3319293710 3319293737 Year: 2016 Publisher: Cham : Springer International Publishing : Imprint: Springer,

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Bringing together the latest information on the organization, management and quality of in-vitro fertilization (IVF) units, this is the first true field guide for the clinician working in assisted reproductive technologies (ART). Divided thematically into four main sections, part one discussed the establishment and organization of the IVF unit, including location, design and construction, practical considerations for batching IVF cycles, and regulations and risk management. Part two, the largest section, covers the many aspects of overall quality management and its implementation – staff and patient management, cryobank and PGD/PGS management, and data management – as well as optimization of treatment outcomes and statistical process control analysis to assess quality variation. Part three addresses the relationship between IVF units and society at large, including the ethics of IVF treatment, as well as public/low-cost and private/corporate IVF units. Advertising and marketing for IVF units is discussed in part four, including the building and managing of websites and the use of traditional print and social media. With approximately five thousand IVF units worldwide and a growing number of training programs, Organization and Management of IVF Units is a key resource for clinic directors, unit managers, embryologists, quality experts, and students of reproductive medicine and clinical embryology.


Book
Development of In Vitro Maturation for Human Oocytes : Natural and Mild Approaches to Clinical Infertility Treatment
Authors: --- ---
ISBN: 3319534548 3319534521 Year: 2017 Publisher: Cham : Springer International Publishing : Imprint: Springer,

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An ideal reference for infertility specialists and reproductive endocrinologists alike, this comprehensive text discusses current natural and mild approaches to in vitro fertilization (IVF) and the development of in vitro maturation (IVM) as a clinical treatment. It is divided thematically into four sections. Part I presents the basic science of ovarian endocrinology and the mechanism of oocyte maturation, including follicular development and the importance of mitochondrial changes. The differences between natural cycle IVF and stimulated IVF are presented in part II, including the standard ovarian stimulation protocols and their outcomes and the etiology, prevention and management of ovarian hyperstimulation syndrome (OHSS). Minimal and mild stimulation for IVF is discussed in part III, including mild stimulation protocols for oncofertility patients and the new minimally invasive INVO procedure. In vitro maturation as a clinical treatment is the subject of part IV, discussing the methodology of immature oocyte retrieval as well as other laboratory aspects and congenital and obstetrical outcomes of babies born from IVM. Combining expertise from thought leaders around the world, Development of In Vitro Maturation for Human Oocytes will be a go-to resource for infertility researchers and practitioners and reproductive endocrinologists working with infertile couples looking for safer and more cost-effective options for treatment.

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