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Social policy --- Hygiene. Public health. Protection --- Surgery --- Human medicine --- Critical Care --- Anesthesia, General. --- Anesthesiology --- Critical Illness. --- Intensive Care Units. --- Perioperative Care. --- Care, Perioperative --- ICU Intensive Care Units --- Intensive Care Unit --- Unit, Intensive Care --- Critically Ill --- Critical Illnesses --- Illness, Critical --- Illnesses, Critical --- Anesthesias, General --- General Anesthesia --- General Anesthesias --- methods.

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Computational fluid dynamics (CFD), which uses numerical analysis to predict and model complex flow behaviors and transport processes, has become a mainstream tool in engineering process research and development. Complex chemical processes often involve coupling between dynamics at vastly different length and time scales, as well as coupling of different physical models. The multiscale and multiphysics nature of those problems calls for delicate modeling approaches. This book showcases recent contributions in this field, from the development of modeling methodology to its application in supporting the design, development, and optimization of engineering processes.

wood dust --- nasal epithelia --- VOCs --- M1dG --- reactive oxygen species (ROS) --- nucleotide excision repair (NER) --- base excision repair (BER) --- oxidative DNA damage --- DNA damage response and repair network --- immune response --- autoimmunity --- systemic lupus erythematosus --- systemic sclerosis --- rheumatoid arthritis --- oxidative stress --- abasic sites --- chromatin organization --- apoptosis --- DNA damage --- general anesthesia --- neuraxial anesthesia --- comet assay --- chronic myeloid leukemia --- genetic instability --- DNA double-strand breaks --- DNA damage response --- benzo[a]pyrene --- BPDE-DNA adduct --- silymarin --- detoxification --- Nrf2 --- PXR --- DNA repair --- base excision repair (BER)glycosylases --- colorectal cancer --- reactive oxygen species --- metabolic adaptation --- drug resistance --- cancer --- thyroid --- thyroid cancer --- volcano --- metals --- metallome --- carcinogens --- hormesis --- environment pollution --- metal biocontamination --- n/a --- Diamond-Blackfan anemia --- 8-oxoguanine --- inflammatory cytokines --- erythrocyte lifespan

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Minimally invasive surgery has become a common term in visceral as well as gynecologic surgery. It has almost evolved into its own surgical speciality over the past 20 years. Today, being firmly established in every subspeciality of visceral surgery, it is now no longer a distinct skillset, but a fixed part of the armamentarium of surgical options available. In every indication, the advantages of a minimally invasive approach include reduced intraoperative blood loss, less postoperative pain, and shorter rehabilitation times, as well as a marked reduction of overall and surgical postoperative morbidity. In the advent of modern oncologic treatment algorithms, these effects not only lower the immediate impact that an operation has on the patient, but also become important key steps in reducing the side-effects of surgery. Thus, they enable surgery to become a module in modern multi-disciplinary cancer treatment, which blends into multimodular treatment options at different times and prolongs and widens the possibilities available to cancer patients. In this quickly changing environment, the requirement to learn and refine not only open surgical but also different minimally invasive techniques on high levels deeply impact modern surgical training pathways. The use of modern elearning tools and new and praxis-based surgical training possibilities have been readily integrated into modern surgical education,which persists throughout the whole surgical career of modern gynecologic and visceral surgery specialists.

ovarian cancer --- laparoscopy --- minimally invasive surgery --- survival --- mortality --- platelet-rich plasma (PRP) --- thin endometrium --- hysteroscopy --- robotic surgery --- sexuality --- laparoscopic hysterectomy --- learning curve --- quality of life --- counseling --- patient-doctor-relationship --- body donors --- surgical education --- clinical anatomy --- live surgery events --- neuropelveology --- LION procedure --- genital nerves stimulation --- chronic pelvic pain --- esophagectomy --- esophageal cancer --- Ivor-Lewis procedure --- health-related quality of life --- cervical cancer --- robotic radical hysterectomy --- recurrence rate --- surgery --- artificial intelligence --- machine learning --- augmented reality --- hysterectomy --- NOTES --- minimally invasive --- systematic review --- meta-analysis --- pediatric surgery --- fetal surgery --- single-incision surgery --- surgical techniques --- surgical devices --- open surgery --- endoscopy --- endoscopic surgery --- cysts of the canal of Nuck --- Nuck hydrocele --- hydrocelectomy --- TAPP --- Lichtenstein --- colorectal liver metastases --- laparoscopic liver surgery --- minimal invasive surgery --- general anesthesia --- anesthetics --- perioperative care --- laparoscopic surgery --- endometrial cancer --- lymphadenectomy --- embryology --- sentinel lymph node mapping --- indocyanine green --- PMMR --- technical aspects --- rectal cancer --- mesorectal --- transanal --- laparoscopic --- local recurrence --- conversion rate --- minimally invasive surgical procedures --- radiotherapy --- ovarian neoplasms --- endometrial neoplasms --- uterine cervical neoplasms --- vaginal neoplasms --- vulvar neoplasms --- survival analysis --- n/a --- video feedback --- video modeling --- gynecology --- surgical training --- pelvitrainer --- prolapse --- pelvic floor --- native tissue --- pectopexy --- robotic assisted surgery --- pancreatic surgery --- pancreaticoduodenectomy --- pelvic floor repair --- laparoscopic repair --- vaginal repair --- mesh use --- VATS --- pain --- postoperative pain control --- thoracic surgery --- lung cancer --- intercostal catheter --- opioid --- regional anaesthesia --- hepatectomy --- single-port laparoscopy --- radiofrequency pre-coagulation --- endometriosis --- endometrioma surgery --- ovarian reserve --- anti-Müllerian hormone --- spontaneous pregnancy --- robotic liver resection --- da Vinci --- intraoperative imaging --- hepatocellular cancer --- real-life imaging --- hepatic metastasis --- COVID-19 --- sars-cov-2 --- surgical performance --- 3D printing --- skill assessment --- snorkel mask --- malabsorption --- Roux-en-Y gastric bypass --- one-anastomosis gastric bypass --- SADI-S --- biliopancreatic diversion --- weight regain --- hepatocellular carcinoma --- cholangiocarcinoma --- risk score --- pelvic compartments --- embryologic development --- oncologic surgery --- pelvic lymphonodectomy --- topographic anatomy --- autonomic pelvic nerves --- uterine cancer --- prostate cancer --- diaphragmatic hernia --- liver resection --- hernia repair --- mesh --- enterothorax --- anti-Müllerian hormone