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The goal of Schistosomiasis is to provide the reader with insights into the active research and programs currently related to schistosomiasis, and to use these insights as a way to project forward into the next 10-15 years of work on this disease, spanning the spectrum from research to public health interventions. A secondary goal of this volume is to initiate conversations among those working across the research-to-control spectrum on schistosomiasis about the future of their field, and by doing so lead to constructive efforts to identify and address the most critical questions and challenges related to schistosomiasis. The book covers four main areas: schistosome phylogenetics, gene expression, and the overall genome, including information on exciting new tools for addressing questions that have long been inaccessible to schistosomologists; the host-schistosome interaction at the larval to adult worm interface and addresses aspects important for vaccine development as well as how differential gene expression as detected by DNA microarrays may be utilized to develop tools for detection and control of infection or pathology; the development of the host immune response to eggs, granuloma formation and factors affecting the development and regulation of immunopathology; and the public health concerns associated with schistosomiasis, including morbidity control, host genetics, treatment and proposals for improved partnerships. The volume concludes with a chapter addressing the schisms that sometimes exist along the spectrum from basic research programs to the implementation of control schemes, and a proposal to make these differences benefit patients and researchers rather than succumb to base temptations to compete for resources to no one’s benefit. Like many of the diseases featured in the World Class Parasites series, the prospects for dramatic advances in schistosomiasis coincide with a seemingly shrinking pool of both human and material resources. The most meaningful progress will occur as the laboratory better understands the needs in the field and the field better understands the capabilities of the laboratory.

Schistosomiasis. --- Distomatosis. --- Distomiasis --- Trematode infections --- Helminthiasis --- Bilharziasis --- Bilharziosis --- Katayama disease --- Snail fever --- Distomatosis --- Morphology (Animals). --- Emerging infectious diseases. --- Animal Anatomy / Morphology / Histology. --- Infectious Diseases. --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Animal morphology --- Animals --- Body form in animals --- Zoology --- Morphology --- Animal anatomy. --- Infectious diseases. --- Animal anatomy --- Biology --- Physiology --- Anatomy

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This book on “Biomphalaria Snails and Larval Trematodes” presents up to date information on the interactions of these snails and their trematode parasites, particularly on Schistosoma spp. larvae. Snails of the genus Biomphalaria are of significant medical importance since several species in this genus are obligate intermediate hosts of the human blood fluke S. mansoni, the causative agent of hepatosplenic schistosomiasis. In addition to the impact of Biomphalaria spp. on public health, these snails are also interesting models for the study of other topics such as population biology, including genetics and demography, proteomics, invertebrate immunobiology, mating systems, biogeography, among others. A purpose of this book is to provide an overview of the recent advances in Biomphalaria spp.-larval trematode interactions, especially in Biomphalaria-schistosome systems. Emphasis is placed on gaps in our knowledge that need to be filled to gain a better understanding of the relationships in these host-parasite systems. This may be critical to obtain a better understanding of our knowledge of the transmission of schistosomiasis and other snail-borne parasitic diseases. The book, “Biomphalaria Snails and Larval Trematodes” is an ideal volume for researchers and advanced students interested in modern aspects of parasitology , malacology and public health.

Biomphalaria. --- Snails. --- Trematoda. --- Biomphalaria --- Trematoda --- Host-parasite relationships --- Schistosomiasis --- Snails as carriers of disease --- Trematode Infections --- Snails --- Platyhelminths --- Host-Pathogen Interactions --- Biology --- Host-Parasite Interactions --- Parasitology --- Helminths --- Biological Processes --- Gastropoda --- Helminthiasis --- Biological Science Disciplines --- Parasitic Diseases --- Mollusca --- Natural Science Disciplines --- Invertebrates --- Biological Phenomena --- Phenomena and Processes --- Diseases --- Disciplines and Occupations --- Animals --- Eukaryota --- Organisms --- Zoology --- Invertebrates & Protozoa --- Microbiology & Immunology --- Health & Biological Sciences --- Parasites --- Larvae --- Host-parasite relationships. --- Schistosomiasis. --- Parasites. --- Larvae. --- Bilharziasis --- Bilharziosis --- Katayama disease --- Snail fever --- Host-organism relationships --- Host-pathogen relationships --- Parasite-host relationships --- Pathogen-host relationships --- Relationships, Host-parasite --- Fluke worms --- Flukes (Platyhelminthes) --- Flukeworms --- Trematode worms --- Trematodes --- Medicine. --- Parasitology. --- Infectious diseases. --- Biomedicine. --- Infectious Diseases. --- Biomedicine general. --- Distomatosis --- Parasitism --- Platyhelminthes --- Planorbidae --- Medical parasitology. --- Emerging infectious diseases. --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Human beings --- Human parasitology --- Parasitic diseases --- Biomedicine, general. --- Health Workforce