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With recent technological advances in multiple research fields such as materials science, micro-/nano-technology, cellular and molecular biology, bioengineering and the environment, much attention is shifting toward the development of new detection tools that not only address needs for high sensitivity and specificity but fulfil economic, environmental, and rapid point-of-care needs for groups and individuals with constrained resources and, possibly, limited training. Miniaturized fluidics-based platforms that precisely manipulate tiny body fluid volumes can be used for medical, healthcare or even environmental (e.g., heavy metal detection) diagnosis in a rapid and accurate manner. These new detection technologies are potentially applicable to different healthcare or environmental issues, since they are disposable, inexpensive, portable, and easy to use for the detection of human diseases or environmental issues—especially when they are manufactured based on low-cost materials, such as paper. The topics in this book (original and review articles) would cover point-of-care detection devices, microfluidic or paper-based detection devices, new materials for making detection devices, and others.

sepsis --- PCT --- procalcitonin --- immunoassay --- antibiotic --- chemiluminescence --- immunofluorescence --- n/a --- origami-based paper analytic device --- origami ELISA --- IgG --- paraquat --- diabetes mellitus --- ketone bodies --- human breath --- acetone --- beta-hydroxybutyrate --- acetoacetate --- gas chromatography-mass spectrometry (GC-MS) --- type 2 diabetes --- diabetic peripheral neuropathy (DPN) --- electrocardiogram (ECG) --- photoplethysmography (PPG) --- percussion entropy index (PEI) --- decision making, computer-assisted --- decision support systems, clinical --- precision medicine --- computational biology --- molecular tumor board --- cBioPortal --- requirements analysis --- neoplasms --- pH value --- diagnosis --- skin --- wound --- blood --- coagulation --- hemostasis --- point of care --- ROTEM --- TEG --- thromboelastography --- VHA --- viscoelastic testing --- partial-thickness burn injury --- burn blister fluid --- P-ELISA --- angiogenin --- burn wound healing --- Alzheimer’s disease --- β-amyloid peptide --- paper-based ELISA --- P-ELISA, point of care testing --- microfluidics --- point-of-care diagnostics --- antimicrobial resistance --- lab-on-a-chip --- capillary-driven flow --- capillary action --- detections --- smartphone imaging --- lateral flow assay --- immuno-chromatographic --- gold nanoparticles sensor --- UV/Vis spectrophotometer --- malaria pan rapid diagnostic strip --- point-of-care --- Alzheimer's disease