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Anti-Bacterial Agents --- Drug Therapy, Combination --- therapeutic use
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Combinational Therapy in Triple Negative Breast Cancer discusses TNBC at the molecular level from a holistic approach, focusing on combinational strategies targeting various pathways involved in this specific cancer type. Using a monotherapy for the treatment of cancer, especially high-grade tumors like TNBC, is mostly worthless due to the inherent genetic instability of tumor cells to develop intrinsic and acquired resistance. Combination therapy presents more, or at least the same, effectiveness with lower doses of every single agent and decreases the likelihood of chemoresistance, making it essential to understand for multiple therapy options.
Breast --- Cancer --- Treatment. --- Triple Negative Breast Neoplasms --- Drug Therapy, Combination --- therapy
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Antirheumatic Agents --- Arthritis, Rheumatoid --- Drug Therapy, Combination --- Randomized Controlled Trials as Topic --- therapeutic use --- drug therapy
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Drug delivery systems. --- Delivery systems, Drug --- Drug administration technology --- Drug delivery technology --- Drugs --- Pharmaceutical technology --- Delivery systems --- Injections, Hypodermic. --- Drug Delivery Systems --- Injections, Subcutaneous --- Hyaluronoglucosaminidase --- Drug Therapy, Combination --- methods --- administration & dosage
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"Combination Drug Delivery Approach as an Effective Therapy for Various Diseases explores the use of bioengineering tools in combination drug delivery approaches to control various diseases at different clinical stages of synergistic action, varying mechanisms of action, and during the suppression of drug resistance. The book presents fundamental knowledge on the experiential and experimental aspects of drug combination approaches in order to equip rational applications in preventing the emergence of resistance during the treatment of various diseases. It provides a holistic understanding of the principles behind formation, characterization, applications, regulations, toxicity, challenges and future perspectives of combination drug delivery approaches."--
Drug delivery systems. --- Delivery systems, Drug --- Drug administration technology --- Drug delivery technology --- Drugs --- Pharmaceutical technology --- Delivery systems --- Chemotherapy. --- Chemotherapy, Combination. --- Drug resistance --- Drug Delivery Systems --- Drug Therapy, Combination --- Drug Synergism --- Drug Resistance --- Prevention.
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Oncology. Neoplasms --- Drug Therapy --- Medicine, East Asian Traditional --- Diseases --- Medicine, Traditional --- Therapeutics --- Culture --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Complementary Therapies --- Anthropology, Cultural --- Anthropology --- Social Sciences --- Anthropology, Education, Sociology and Social Phenomena --- Medicine, Chinese Traditional --- Neoplasms --- Drug Therapy, Combination
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Pathological dermatology --- Pharmacology. Therapy --- Drug Therapy, Combination. --- Skin Diseases --- Acne Vulgaris --- Hirsutism --- Androgen Antagonists --- Chemotherapy, Combination --- Combination Drug Therapy --- Drug Polytherapy --- Therapy, Combination Drug --- Combination Chemotherapy --- Polychemotherapy --- Chemotherapies, Combination --- Combination Chemotherapies --- Combination Drug Therapies --- Drug Polytherapies --- Drug Therapies, Combination --- Polychemotherapies --- Polytherapies, Drug --- Polytherapy, Drug --- Therapies, Combination Drug --- Drug Combinations --- Polypharmacy --- drug therapy. --- therapeutic use. --- Drug Therapy, Combination --- drug therapy --- therapeutic use --- Anti-androgenes --- Dermatologie --- Oestrogenes
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Early clinical trials of the new molecular-based anticancer agents have shown that many are marginal in controlling cancer, but prove to be potent modulators and potentiators of chemotherapy-induced apoptosis when used in combination with classic cytotoxic drugs or radiation. In Combination Cancer Therapy: Modulators and Potentiators, expert physician-scientists and clinicians with first-hand experience in the clinical development of targeted therapies review those combinations that hold the most promise for the future of medical oncology, detailing their optimal sequence, pharmacokinetic interactions, and interaction with downstream cellular signals. The combinations run the gamut of targeted therapies against cell surface receptors (EGF-R and HER2), the cell cycle (the CDKs), signal transduction events (PKC and NF-kB), apoptosis (bcl-2), as well as focused therapies in ovarian cancer, hematologic diseases, and breast cancer. The authors emphasize novel translational approaches that are rapidly moving from the laboratory benchtop to the patient's bedside as a new generation of cancer therapeutics. Cutting-edge and forward-looking, Combination Cancer Therapy: Modulators and Potentiators offers everyone in the fields of cancer drug development and therapy a powerful new understanding of the optimal sequencing and scheduling of new combination drug therapies necessary to maximize the effects for cancer patients today.
Neoplasms --- Drug Therapy, Combination. --- Cancer --- Apoptosis. --- Apoptose --- drug therapy. --- Chemotherapy. --- Treatment. --- Chimiothérapie --- Traitement --- Apoptosis --- Drug Therapy, Combination --- Chemotherapy --- Treatment --- drug therapy --- Cancer -- Chemotherapy. --- Cancer -- Treatment. --- Drug Therapy --- Therapeutics --- Diseases --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Oncology --- Medicine --- Health & Biological Sciences --- Cancer therapy --- Cancer treatment --- Therapy --- Medicine. --- Oncology. --- Medicine & Public Health. --- Tumors --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Cell death --- Antineoplastic agents --- Oncology . --- Cancer - Chemotherapy --- Cancer - Treatment --- Neoplasms - drug therapy
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Neuropathology --- Toxicology --- Pharmacology --- Nervous system --- Drug Therapy --- Poisoning --- Système nerveux --- Toxicologie --- Drug effects --- adverse effects --- Diseases --- Maladies --- Neurotoxicology. --- Pharmacology. --- Drug therapy --- Poisoning. --- Drug effects. --- Adverse effects. --- Système nerveux --- Diseases. --- Nervous System --- drug effects. --- Drug-Related Side Effects and Adverse Reactions. --- Neurotoxicology --- Drug Therapy, Combination
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