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Digital
Handbook of Neurochemistry and Molecular Neurobiology : Practical Neurochemistry Methods
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ISBN: 9780387304014 Year: 2007 Publisher: Boston, MA Springer-Verlag

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Handbook of Neurochemistry and Molecular Neurobiology : Behavioral Neurochemistry, Neuroendocrinology and Molecular Neurobiology
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ISBN: 9780387304052 Year: 2007 Publisher: Boston, MA Springer-Verlag

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Digital
Handbook of Neurochemistry and Molecular Neurobiology : Brain Energetics. Integration of Molecular and Cellular Processes
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ISBN: 9780387304113 Year: 2007 Publisher: Boston, MA Springer-Verlag

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Digital
Handbook of Neurochemistry and Molecular Neurobiology : Amino Acids and Peptides in the Nervous System
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ISBN: 9780387303734 Year: 2007 Publisher: Boston, MA Springer Science+Business Media, LLC

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Handbook of Neurochemistry and Molecular Neurobiology : Acute Ischemic Injury and Repair in the Nervous System
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ISBN: 9780387303833 Year: 2007 Publisher: Boston, MA Springer-Verlag

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Handbook of Neurochemistry and Molecular Neurobiology : Neurotransmitter Systems
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ISBN: 9780387303826 Year: 2008 Publisher: Boston, MA Springer Science+Business Media, LLC

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The brain is the organ that collects information from the environment, processes and stores the information, and generates behavior as and when needed. In essence, the brain makes us who we are. For this reason, understanding the biology of brain function is a great challenge and a major goal of modern science. The brain is one of the last great frontiers in science, and the unraveling of its mysteries is comparable in complexity to efforts in space exploration. A fundamental goal of neuroscience is to understand how neurons generate behavior and the pathophysiology of different mental and neurological diseases. This requires, among other things, information about where these neurons are located, how they are connected, and how they communicate with each other in various physiological and pathophysiological conditions. Our aim is to describe recent discoveries about the basic operations of the brain and to provide an introduction to the adaptations for specific types of information processing.


Multi
Handbook of Neurochemistry and Molecular Neurobiology : Neuroimmunology
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ISBN: 9780387303987 Year: 2008 Publisher: Boston, MA Springer Science+Business Media, LLC

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This volume contains data on multiple immunomodulators, many of which are also the products of hypothalamic brain cell neurosecretion. Interleukins (IL-1a, IL-1ß, IL-2, IL-4, IL-6, TNFa), immunophylin and ubiquitin as well as proline rich peptides, comprised of 10-15 amino acids are being produced in N. Supraopticus and N. Paraventricularis and then secreted into neurohypophysis. Along the neurosecretion of the mentioned cytokines, there are other immunomodulators, the primary structure of which had been completely deciphered such as: Immunophyllins, intracellular receptors of immunosuppressors FK506, cyclosporine A., rapamicin. They are peptidyl-prolyl-cis-trans-isomerases. There are novel immunological hypothalamic factors such as ubiquitin, macrophage migration inhibitory factor (MIF), as well as Thymosin ß 4(1-39). This data allowed us to propose the concept of neuroendocrine immune system of the brain.


Periodical
Axon
ISSN: 08347824 Publisher: Boucherville

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Digital
Neurotoxicity of Metals
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ISBN: 9783319601892 Year: 2017 Publisher: Cham Springer International Publishing

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In this book, international authorities address contemporary research in metal neurotoxicity. Essential and non-essential metals play an important role in neurodevelopmental and neurodegenerative diseases. Recent developments in understanding the role of metals in the etiology of these disorders have led to rapid growth in clarifying the pathology of some of the most devastating diseases we face and in identifying potential new therapies. Few books or periodicals have been wholly dedicated to the topic of metals, and this collection is intended to serve as a resource for all researchers interested in metals and their role in health and disease.


Digital
Toxicity and Autophagy in Neurodegenerative Disorders
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ISBN: 9783319139395 9783319139401 9783319139388 9783319382128 Year: 2015 Publisher: Cham Springer International Publishing

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Comprehensive overview of different aspects of autophagy as it relates to neurodegenerative diseases. The pathogenesis of the main neurodegenerative disorders includes either the accumulation of altered or misfolded proteins or exposure to several toxics. Autophagy constitute one of the two principal cellular pathways implicate in the clearance of these material and can serve as a neuroprotective mechanism. Topics include: the role of autophagy in the brain, the role of autophagy in the principal neurodegenerative disorders, and the mechanism by which different molecules cause neurotoxicity and the role autophagy plays.

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