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This book gathers relatively recent and significant topics in the field of ion channel research. Ion channels form the molecular basis for membrane excitability in cells from the cardiovascular and nervous systems. In many non-excitable cells, ion channels contribute to diverse function including secretion of signaling compounds like hormones and insulin, cell volume regulation, intracellular signaling especially Ca2+ signaling, etc. Many human diseases have been attributed to abnormal channel functions and defective membrane expression of channel proteins. On the other hand, ion channels are excellent models for studying protein biophysics, especially the allosteric regulation of protein function by miscellaneous stimuli. Therefore, researches on ion channels carry significant meaning for the understanding of basic protein biophysics and diverse physiological functions and for developing novel and effective treatment for related human diseases. This book could provide graduates and scientists in both basic and clinical levels, a comprehensive understanding of cutting-edge advances and a useful and stimulating platform for tackling their own questions about ion channels.
Histology. Cytology --- Biology --- Human physiology --- celmembranen --- biologie --- fysiologie --- Ion channels. --- Ion channels --- Canals iònics --- Biologia --- Fisiologia --- Research --- Methodology. --- Biologia.
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This book covers the molecular structures and the cellular and in vivo function of endosomes and lysosomes, i.e. intracellular vesicles which are involved in many cellular processes such as endocytosis, intracellular trafficking, degradation of material from inside (e.g. autophagy) and outside the cell as well as exocytosis. Membranes of endolysosomal organelles contain an amazing number and diversity of ion channels. These ion channels are the topic of the present book that focusses on describing the structure, the biophysical properties, physiological functions of endolysosomal ion channels at the molecular, cellular and in vivo level. .
Histology. Cytology --- Biology --- History of human medicine --- Human physiology --- farmacologie --- biologie --- fysiologie --- cytologie --- histologie --- Endosomes. --- Ion channels. --- Lysosomes.
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Biological transport --- Ion channels --- Cell receptors --- Transport biologique --- Canaux ioniques --- Récepteurs cellulaires --- Periodicals. --- Periodicals --- Périodiques --- Biological Transport. --- Ion Channels. --- Receptors, Cell Surface. --- Cell Surface Hormone Receptors --- Endogenous Substances Receptors --- Cell Surface Receptors --- Hormone Receptors, Cell Surface --- Receptors, Endogenous Substances --- Binding Sites --- Hormones --- Ligands --- Receptor Cross-Talk --- Ion Channel --- Ionic Channel --- Ionic Channels --- Membrane Channel --- Membrane Channels --- Channel, Ion --- Channel, Ionic --- Channel, Membrane --- Channels, Ion --- Channels, Ionic --- Channels, Membrane --- Signal Transduction --- Biologic Transport --- Transport, Biological --- Transport, Biologic --- Transport Vesicles --- Membrane Transport Proteins --- Chemistry --- Life Sciences --- Biochemistry --- Biology --- Physics --- Cell Surface Receptor --- Receptor, Cell Surface --- Surface Receptor, Cell --- Biological Transport --- Ion Channels --- Receptors, Cell Surface
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