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Der Autor untersucht die Tradition der Graphomanie in der russischen Literatur des 19 und 20 Jh. und stellt sich die Frage, wozu sie in dieser Literatur und insbesondere bei Chlebnikov eingesetzt wird.

Graphomanie --- Hypothetischer Realismus --- Konzeptualisierung --- Kunst und Obsession --- Literatur --- Moskauer Konzeptualisten --- Pianca --- postmodernen --- russischsprachigen --- Schizophrenie und Kunst --- Tchouboukov

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Major depression and obsessive–compulsive disorder (OCD) are now recognized among the most frequent psychiatric disorders, affecting 16–17% and 2–3% of the general population, respectively. They are commonly characterized by: i) a high level of psychiatric and somatic comorbidities; ii) a recurrence or chronic profile; and iii) a negative impact on daily functions, thereby leading to a profound impairment of quality of life. Despite significant advances in pharmacological and psychological therapies over the last decades, unsuccessful responses to standard treatment strategies are classically observed in approximately 20–30% of cases. Therefore, there is a significant need for improving the pathophysiological knowledge through a better identification of environmental, clinical, psychological, genetic, anatomical, and biological determinants, specifically implied in the development, the phenotypic expression, and the relapsing course and/or contributing to the therapeutic failure in major depression and OCD. We are convinced that this research approach is particularly relevant providing critical support for the promotion of innovative treatment alternatives potentially useful for the management of resistant forms of major depression and OCD.

n/a --- i-health --- olfaction --- psychiatry --- obsession --- obsessive–compulsive disorder --- transcranial direct current stimulation --- ecological momentary assessment --- Streptococcus pyogenes --- cytokines --- immunology --- compulsion --- cognition --- nosography --- pediatric autoimmune neuropsychological disorders associated with streptococcal infection (PANDAS) --- symptoms networks --- brain stimulation --- neuromodulation --- OCD --- m-health --- categorizations --- ecological momentary intervention --- fictional case study --- pediatric acute-onset neuropsychiatric syndrome (PANS) --- Toxoplasma gondii --- tDCS --- therapeutic tool --- depression --- markers --- quality of life --- Tourette syndrome --- Obsessive-compulsive disorder. --- Depression, Mental. --- Dejection --- Depression, Unipolar --- Depressive disorder --- Depressive psychoses --- Melancholia --- Mental depression --- Unipolar depression --- Affective disorders --- Neurasthenia --- Neuroses --- Manic-depressive illness --- Melancholy --- Sadness --- Compulsive disorder --- Fixed ideas --- Obsession (Psychology) --- Obsessive-compulsive neuroses --- Obsessive-compulsive neurosis --- OCD (Disease) --- Compulsive behavior --- Bipolar disorder --- obsessive-compulsive disorder

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This book represents one of the most up-to-date collections of articles on clinical practice and research in the field of Autism Spectrum Disorders (ASD). The scholars who contributed to this book are experts in their field, carrying out cutting edge research in prestigious institutes worldwide (e.g., Harvard Medical School, University of California, MIND Institute, King’s College, Karolinska Institute, and many others). The book addressed many topics, including (1) The COVID-19 pandemic; (2) Epidemiology and prevalence; (3) Screening and early behavioral markers; (4) Diagnostic and phenotypic profile; (5) Treatment and intervention; (6) Etiopathogenesis (biomarkers, biology, and genetic, epigenetic, and risk factors); (7) Comorbidity; (8) Adulthood; and (9) Broader Autism Phenotype (BAP). This book testifies to the complexity of performing research in the field of ASD. The published contributions underline areas of progress and ongoing challenges in which more certain data is expected in the coming years. It would be desirable that experts, clinicians, researchers, and trainees could have the opportunity to read this updated text describing the challenging heterogeneity of Autism Spectrum Disorder.

autism spectrum disorder --- infants --- frontal EEG alpha asymmetry --- early detection --- autism spectrum disorders --- toddlers --- eye tracking --- joint attention --- longitudinal --- regression --- cytokines --- PAI-1 --- neuroinflammation --- gastrointestinal --- autism --- literature review --- comorbidity --- early intervention --- early intensive behavioral intervention --- behavioral intervention --- First Year Inventory --- early screening --- risk --- cross-cultural generalisability --- validity --- preschool teachers --- self-efficacy --- knowledge --- belief --- skills --- identify --- autism spectrum disorder (ASD) --- level 1 and level 2 screening tools --- systematic review --- COSMIN --- PRISMA --- screening --- infection --- prion --- meta-analysis --- motion analysis --- video signal processing --- neurodevelopmental disorders --- infant screening --- n/a --- developmental language disorder --- semantic features --- word learning --- central coherence --- biomarker --- p-cresol --- mouse social behavior --- dopamine --- ASD --- vision --- proprioception --- self-motion --- immersive virtual reality --- IVR --- HMD --- technology --- persuasive text writing --- perspective-taking --- adolescence --- intervention --- sign language --- imitation --- cognition --- language acquisition --- prevalence estimate --- predictors --- surveillance review --- Autism Spectrum Disorder (ASD) --- early intensive intervention --- developmental trajectories --- moderators and mediators of intervention. --- psychosis --- schizophrenia --- psychopathology --- AQ --- accuracy --- attention to detail --- self-awareness --- insight --- preconception risk factor --- Gilles de la Tourette --- obsession --- compulsion --- social behavior --- social impairment --- sensory profile --- sensory responsiveness --- feeding problems --- short sensory profile (SSP) --- sensory experience questionnaire (SEQ) --- coronavirus --- 2019-nCoV --- neurodevelopment --- child and adolescent psychiatry --- mental health prevention --- Asperger syndrome --- adults --- cerebrospinal fluid --- antibodies --- blood–brain barrier --- GAD65 --- Early Start Denver Model --- high-risk infants --- motor development --- high-functioning autism --- language --- experience --- communication --- autonomic nervous system --- wearable technologies --- EEG --- theory of mind --- adults and adolescents --- human figure drawings --- Draw-a-Man --- drawings maturity --- social perception --- ERP --- reward response --- RewP --- sensitization --- social skills intervention --- PEERS® --- adulthood --- diagnosis --- autistic traits --- action observation --- action prediction --- context --- priors --- hypothalamus --- amygdala --- oxytocin --- social cognition --- social interaction --- affiliative behavior --- neuroimaging --- COVID-19 --- challenging behavior --- dental care --- oral health --- medical procedures --- ICT --- wearable sensors --- migration --- Europe --- health system --- autism in adulthood --- intellectual disability --- regressive autism --- epilepsy --- challenging behaviors --- empathy --- executive functions --- attention deficit and hyperactivity disorder --- disruptive behavior disorders --- alexithymia --- anxiety --- depression --- TAS-20 --- TSIA --- parents --- broader autism phenotype --- autistic-like features --- social-cognitive development --- stereotypical behaviors --- visual impairment --- language profiles --- grammatical comprehension --- cannabinoids --- cannabidiol --- cannabidivarin --- THC --- problem behaviors --- sleep --- hyperactivity --- side effects --- motor performance skills --- Gulf --- BOT-2 --- machine learning --- employment --- telehealth --- ABA --- RCT --- cortisol --- group activity --- stress --- art --- assessment --- sensorimotor integration --- postural balance --- false positive report probability (FPRP) --- Bayesian false-discovery probability (BFDP) --- Genome-Wide Association Studies (GWAS) --- microbiome --- metabolomics --- study design --- biomarker discovery --- precise medicine --- bipolar disorder --- suicidal ideation --- suicidal attempts --- blood-brain barrier