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The book deals with therapeutic monoclonal antibodies (mAbs) broadly, and relevant topics such as challenges and opportunities, next-generation antibody products, Antibody-Drug-Conjugates (ADC), bispecifics, glycosylation, and T-cell engagers are covered. Each topic has been written by leading groups around the world and the book should be of interest to researchers from both academia and industry.

Pharmaceutical industry.

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"At present India is a leading producer, distributor, and consumer of generic medicines globally. Disparate Remedies traces the genealogy of this development and examines the public cultures of medicine in the country between 1870 and 1960. The book begins by discussing the expansion of medical consumerism in late nineteenth-century India when British-owned firms extended their sales to distant provincial towns. As a result, laboratory-produced drugs competed with traditional street remedies through side-by-side production of 'Western' and 'Indian' drugs by pharmaceutical companies. The emergent middle classes, the creation of a public sphere, and nationalist politics transformed the medical culture of modern India and generated conflict between Western and Indigenous medical systems and their practitioners. Nandini Bhattacharya demonstrates that these disparate therapies were sustained through the tropes of purity or adulteration, potency or lack of it, and epistemic heritage, even when their material configuration often differed little. Uniquely engaging with the cultures of both consumption and production in the country, Disparate Remedies follows the evolution of medicine in colonial India as it confronted Indian modernity and changing public attitudes surrounding health and drugs."-- Provided by publisher.

Pharmaceutical industry.

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The book broadly deals with therapeutic monoclonal antibodies (mAbs) and various relevant topics, including different antibody formats such as Antibody-Drug Conjugates (ADC), bispecifics, nanoparticle-based mAbs and HER2+ cancers, immune checkpoint inhibitors and other closely related topics. Each paper was written by leading active research groups in their fields both from academia and industry. The book should be of interest to those scientists and researchers who develop or use biologics, biotherapeutics, biosimilars and biobetters in cancer treatment.

Pharmaceutical industry.

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Die Studie untersucht den bedeutenden mittelalterlichen Druckort Speyer, wo zwischen 1471 und 1500 vier unterschiedliche Druckereien tätig waren. Neben der wichtigsten Werkstatt der Familie Drach, die von Peter Drach d. Ä. 1475 begründet wurde, druckten dort Johann und Conrad Hist sowie zwei anonyme Offizinen. Aufbauend auf deren Biographien wird die Speyerer Inkunabelproduktion systematisch im Hinblick auf die Inhalte, die Gestaltung, die Papierbeschaffung und den -gebrauch sowie die zeitgenössische Verbreitung untersucht und verglichen. Die Studie kann dafür auf den reichhaltigen Überlieferungsbestand von über 7000 Exemplaren von gut 300 Ausgaben zurückgreifen, die durch Kataloge und Autopsie erschlossen wurden. Ergänzend zu zahlreichen Archivalien und Paratexten in den Drucken wurde das Rechnungsbuch Peter Drachs d. M. untersucht, das eine einzigartige Quelle für den deutschsprachigen Raum darstellt. Mit der systematischen Auswertung des Rechnungsbuchs und der überlieferten Inkunabeln sowie der Analyse der verwendeten Papiere versteht sich der vorliegende Band zum einen als Fallstudie für massenhaften Papiergebrauch im Spätmittelalter und bietet zum anderen neue methodische Perspektiven für die Inkunabelforschung.

Printing industry.