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Optofluidics combines and integrates optics and fluidics to produce versatile systems that are achievable only with difficulty through either field alone. With the spatial and temporal control of the microfluids, the optical properties can be varied, providing highly flexible, tunable, and reconfigurable optical systems. Since the emergence of optofluidics, numerous systems with varied configurations have been developed and applied to imaging, light routing, bio-sensors, energy, and other fields. This Special Issue aims to collect high quality research papers, short communications, and review articles that focus on optofluidics, micro/nano technology, and related multidisciplinary emerging fields. The special issue will also publish selected papers from the 5th Optofluidics 2015 conference (http://www.optofluidics2015.org/), 26–28 July 2015, Taipei, Taiwan. The aim of optofluidics 2015 conference is to provide a forum to promote scientific exchange and to foster closer networks and collaborative ties between leading international optics and micro/nanofluidics researchers across various disciplines. The scope of Optofluidics 2015 is deliberately broad and interdisciplinary, encompassing the latest advances and the most innovative developments in micro/nanoscale science and technology. Topics range from fundamental research to its applications in chemistry, physics, biology, materials and medicine.

droplets and emulsions --- energy and environment --- optofluidic & 3D displays --- micro-/nano-fluidics --- plasmonics and metamaterials --- fabrication and materials --- biochemical sensors and assays --- optical imaging and light sources --- optical devices and systems

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The recent global events of the SARS-CoV-2 pandemic in 2020 have alerted the world to the urgent need to develop fast, sensitive, simple, and inexpensive analytical tools that are capable of carrying out a large number of quantitative analyses, not only in centralized laboratories and core facilities but also on site and for point-of-care applications. In particular, in the case of immunological tests, the required sensitivity and specificity is often lacking when carrying out large-scale screening using decentralized methods, while a centralized laboratory with qualified personnel is required for providing quantitative and reliable responses. The advantages typical of electrochemical and optical biosensors (low cost and easy transduction) can nowadays be complemented in terms of improved sensitivity by combining electrochemistry (EC) with optical techniques such as electrochemiluminescence (ECL), EC/surface-enhanced Raman spectroscopy (SERS), and EC/surface plasmon resonance (SPR). This Special Issue addresses existing knowledge gaps and aids in exploring new approaches, solutions, and applications for opto-electrochemical biosensors in the quantitative detection of disease markers, such as cancer biomarkers proteins and allergens, and pathogenic agents such as viruses. Included are seven peer-reviewed papers that cover a range of subjects and applications related to the strategies developed for early diagnosis.

gold nanoparticles --- doxycycline --- tetracycline --- SPR biosensor --- signal amplification --- clinical diagnosis --- microRNA --- electrochemical biosensor --- catalysts --- RedOx indicator --- cancer biomarker --- electrochemical immune platform --- human ST2 --- plasma --- pancreatic cancer --- collagen type I --- 4,4′-thiobisbenzenethiol --- nanogold --- electrochemical impedance spectroscopy --- surface plasmon resonance --- half antibody --- medical diagnostic devices --- peptide --- antifouling --- protease --- biomarker --- bioreceptor --- SARS-CoV-2 detection --- nasopharyngeal swab --- saliva --- serum --- droplets --- amperometric biosensor --- neural esterase --- acetylcholinesterase --- inhibition --- organophosphate --- design --- optimization --- mathematical model --- flux control --- dimensionless --- n/a --- 4,4'-thiobisbenzenethiol

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Biopolymers including natural (e.g., polysaccharides, proteins, gums, natural rubbers, bacterial polymers), synthetic (e.g., aliphatic polyesters and polyphosphoester), and biocomposites are of paramount interest in regenerative medicine, due to their availability, processability, and low toxicity. Moreover, the structuration of biopolymer-based materials at the nano- and microscale along with their chemical properties are crucial in the engineering of advanced carriers for drug products. Finally, combination products including or based on biopolymers for controlled drug release offer a powerful solution to improve the tissue integration and biological response of these materials. Understanding the drug delivery mechanisms, efficiency, and toxicity of such systems may be useful for regenerative medicine and pharmaceutical technology. The main aim of the Special Issue on “Biopolymers in Drug Delivery and Regenerative Medicine” is to gather recent findings and current advances on biopolymer research for biomedical applications, particularly in regenerative medicine, wound healing, and drug delivery. Contributions to this issue can be as original research or review articles and may cover all aspects of biopolymer research, ranging from the chemical synthesis and characterization of modified biopolymers, their processing in different morphologies and hierarchical structures, as well as their assessment for biomedical uses.

curcumin --- pectin aerogels --- chitosan coating --- burst release --- controlled release --- Keratose --- drug-coated balloon --- paclitaxel --- drug delivery --- pre-clinical --- peripheral arterial disease --- endovascular --- cellulose phosphate --- cellulose phosphate aerogel --- interconnected porosity --- supercritical carbon dioxide --- tetrabutylammonium fluoride --- TBAF/DMSO --- polysaccharide --- κ-carrageenan --- dexamethasone --- electrochemical active deliver system --- doping agent --- charged molecule --- conductive polymers --- colorectal cancer --- antioxidants --- 5-fluorouracil --- polymer nanomaterials --- nanocapsules --- chemotherapy --- cryogel --- starch --- NMR spectroscopy --- morphology --- drug release --- polysaccharides --- hydrogels --- prilling --- droplets --- ionotropic gelation --- drying --- xerogels --- cryogels --- aerogels --- lipid microparticles --- PGSS® --- supercritical CO2 --- modeling --- solvent-free technology --- biomaterials --- porous materials --- biomimetic --- multi-stimulation --- tissue engineering --- n/a

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The miniaturization of components in mechanical and electronic equipment has been the driving force for the fast development of micro/nanosystems. Heat and mass transfer are crucial processes in such systems, and they have attracted great interest in recent years. Tremendous effort, in terms of theoretical analyses, experimental measurements, numerical simulation, and practical applications, has been devoted to improve our understanding of complex heat and mass transfer processes and behaviors in such micro/nanosystems. This Special Issue is dedicated to showcasing recent advances in heat and mass transfer in micro- and nanosystems, with particular focus on the development of new models and theories, the employment of new experimental techniques, the adoption of new computational methods, and the design of novel micro/nanodevices. Thirteen articles have been published after peer-review evaluations, and these articles cover a wide spectrum of active research in the frontiers of micro/nanosystems.

Darcy-Forchheimer theory --- nonlinear stretching --- nanofluid --- magnetohydrodynamics --- convective conditions --- carbon nanotubes --- thermal radiation --- porous cavity --- wavy channels --- nanofluids --- forced convection --- heat enhancement --- pressure drop --- mesh model --- microfluidic --- flow distributions --- fluid network --- microchannel --- heat transfer enhancement --- numerical simulation --- monodisperse droplet generation --- satellite droplets --- piezoelectric method --- droplet coalescence --- lattice Boltzmann method --- inertial migration --- Poiseuille flow --- pulsatile velocity --- loop heat pipe --- deionized water --- two-phase flow --- visualization --- heat transfer experiment --- heat transfer --- porous media --- pore-scale modeling --- boundary condition --- thermal conductivity --- porosity --- conjugate interface --- aspect ratio --- Maxwell nanofluid --- Darcy–Forchheimer model --- chemical reaction --- Brownian diffusion --- wearable device --- microfluidic chip --- sweat collecting --- microfluidics --- liquid metal --- measurement --- temperature monitoring --- PCR --- pin-fins --- wavy pin-fins channel --- performance criterion --- friction factor --- n/a --- Darcy-Forchheimer model

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Digital agriculture is gaining traction among scientists implementing different new and emerging sensor technologies to monitor complex soil–plant–atmosphere interactions in an accurate, cost-effective and user-friendly manner. This book presents some of the latest advances in this emerging area of research. The diversity of applications in which digital agriculture can make an important difference in day-to-day farming decision making makes this discipline an important focus of research internationally.

apple orchards --- modeling and simulation --- unmanned aerial vehicles --- fruit ripeness --- ethylene gas detection --- 3D crop modeling --- remote sensing --- on-ground sensing --- depth images --- parameter acquisition --- capacitor sensor --- deposit mass --- pesticide droplets --- formulations --- ionization --- CFD --- airflow field test --- monitoring method --- spectral sensor --- crop growth --- computer vision --- deep learning --- image processing --- pose estimation --- animal detection --- precision livestock --- Citrus sinensis L. Osbeck --- mechanical harvesting --- acceleration sensor --- vibration time --- logistic regression --- adaptive thresholding --- fruit detection --- parameter tuning --- phenotype --- phenotyping --- phenomics --- Triticum aestivum --- water deficit --- stress --- infrared --- leaf area index --- cocoa beans --- volatile compounds --- artificial neural networks --- VitiCanopy app --- bushfires --- infrared thermography --- near-infrared spectroscopy --- smoke taint --- artificial intelligence --- Kinect sensor --- RGB --- RGB-D --- image segmentation --- colour thresholding --- bunch area --- bunch volume --- point cloud --- mesh --- surface reconstruction --- image analysis --- cluster morphology --- machine learning --- non-invasive sensing technologies --- proximal sensing --- precision viticulture --- partial least square --- support vector machine --- Gaussian processes --- soybean --- pigeon pea --- guar --- tepary bean --- n/a