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Professor Lal has been remarkably successful in combining scholarship with autobiography in Mr Tulsi's Store.
Regions & Countries - Australia & Pacific Islands - Oceania --- History & Archaeology --- Immigrants --- East Indians --- Lal, Brij V. --- Asian Indians --- Indians, East --- Indic peoples --- Emigrants --- Foreign-born population --- Foreign population --- Foreigners --- Migrants --- Lāla, Br̥ja Vilāśa --- Ethnology --- Persons --- Aliens
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Beyond being the most important natural compound source, actinomycetes are the origin of up to two-thirds of all clinically used antibiotics. Currently, new antimicrobials are urgently needed, as infections caused by antibiotic-resistant pathogens are on the rise. In the identification of new antibiotics, many scientists are currently investigating biosynthetic aspects of antibiotic production in actinomycetes. Since the emergence of next-generation sequencing technologies, the field of antibiotics research has experienced a remarkable revival. These bacteria have the potential to produce more antibiotics than previously thought possible. Some antibiotics are produced in standard media, while others require the presence of a specific signaling molecule in the medium. Others, however, are only produced when the native regulation of the biosynthesis gene cluster is overruled. This book covers topics in the field of antibiotic-producing actinomycetes. The following tops are addressed: - Approaches to access novel antibiotic producers for novel natural compounds - Omics and genome mining approaches for the discovery of novel natural compounds - Analyses and genetic engineering of antibiotic biosynthesis - Regulation of the secondary metabolism in actinomycetes
Streptomyces --- biogeography --- comparative genomics --- diversification --- secondary metabolite biosynthetic gene clusters --- SMGC --- natural products --- streptomyces --- rishirilide --- biosynthesis --- polyketides --- polynucleotide phosphorylase --- ribonuclease --- regulation --- promoter --- RNA decay --- polyadenylation --- (p)ppGpp --- antibiotic --- antibiotics --- geomicrobiology --- Illumina sequencing --- microbiome diversity --- Actinobacteria --- Cave microbiology --- secondary metabolite --- rare Actinobacteria --- Amycolatopsis --- unculturability --- siderophore --- glycopeptide antibiotics --- dbv cluster --- regulatory genes --- StrR --- LAL --- LuxR solo --- dalbavancin --- A40926 --- Streptomyces lividans --- secretion pathways --- secretory proteins --- signal peptides --- actinomycetes --- teicoplanin --- van resistance genes --- Streptomyces tsukubaensis --- tacrolimus --- FK506 --- omics --- screening --- secondary metabolism --- differentiation --- elicitors --- morphology --- liquid cultures --- metagenomics --- rare actinomycetes --- dereplication --- metabolomics --- genome mining --- secondary metabolites --- novel compounds --- physicochemical screening --- physical and chemical properties --- structural diversity --- biological activity --- Actinoallomurus --- antibiotics polyethers --- lysolipin --- minimal PKS II --- cyclases --- benz[a]naphthacene quinone --- tridecaketide --- aromatic polyketide --- pentacyclic angular polyphenol --- extended polyketide chain --- actinobacteria --- β-lactamase --- resistance --- β-lactamase inhibitor --- polyketide synthases --- acyltransferases --- engineering --- new bioactive compounds --- symbiosis --- drug discovery --- chemical ecology --- culture-based approaches --- strain --- specialized metabolites --- biosynthetic gene cluster --- n/a
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‘What I have sought to do in my work is to give voiceless people a voice, place and purpose, the sense of dignity and inner strength that comes from never giving up no matter how difficult the circumstances. History belongs as much to the vanquished as to the victors.’ — Brij V. Lal. ‘Professor Brij Lal is the finest historian of the Indian indentured experience and the Indian diaspora. His Girmitiyas is a classic.’ — Emeritus Professor Clem Seecharan, London Metropolitan University. ‘Brij Lal is a highly respected, versatile and imaginative scholar who has made a lasting contribution to the historiography of the Pacific.’ — Dr Rod Alley, Victoria University of Wellington. ‘Professor Brij Lal’s life is a remarkable journey of a scholar and an intellectual whose writings are truly transformative; a man of moral clarity and courage who also has deep pain at being cut off from his homeland.’ — Professor Michael Wesley, Dean of the College of Asia and the Pacific, The Australian National University. ‘Brij Lal is a singular scholar, whose work has spanned disciplines – from history, political commentary, encyclopedia, biography and “faction”. Brij is without doubt the most eminent scholar in the humanities and social sciences Fiji has ever produced. He also remains one of the most significant public intellectuals of his country, despite having been banned from entering it in 2009.’ — Emeritus Professor Clive Moore, University of Queensland. ‘Brij Lal is an accomplished and versatile historian and true son of Fiji. Above all, there is affirmation here of the enduring worth of good literature and the value of good education that Lal received and wants others to experience. The world needs more Lals who speak out against ruling opinions and dare to stray into the pastures of independent thought.’ — Professor Doug Munro, historian and biographer, Wellington, and Adjunct Professor at the University of Queensland
Lal, Brij V. --- Lāla, Br̥ja Vilāśa --- Oceania --- Australasian & Pacific history --- Fiji --- history --- Social life and customs. --- Politics and government. --- Fig'i --- Iye Fig'i --- Feejee --- Feejee Islands --- Fiji Islands --- Fei-chi kuo --- Fei-chi --- Fei-chi chʻün tao --- Fidschi --- Republic of Fiji --- Republic of the Fiji Islands --- Fijian Republic --- Matanitu ko Viti --- Matanitu Tu-Vaka-i-koya ko Viti --- Fijī Ripablik --- Fidji --- Fichi --- Republica d'as Islas Fichi --- Ficgiege --- Fixi --- República de les Islles Fixi --- Fici adaları --- Фіджы --- Fidz︠h︡y --- Fidži --- Republika Fidži ostrva --- Фиджи --- Fidzhi --- Република Фиджи --- Republika Fidzhi --- Fidžijská republika --- Gweriniaeth Ynysoedd Fiji --- Republik Fidschi-Inseln --- Fííjii --- Fidži Vabariik --- Φίτζι --- Phitzi --- Δημοκρατία των Νησιών Φίτζι --- Dēmokratia tōn Nēsiōn Phitzi --- Fiyi --- República de las Islas Fiyi --- Fiĝioj --- Fiji uharteetako Errepublika --- République des îles Fidji --- Fidzjy --- Fidsí --- Poblacht Oileán Fhidsí --- Pobblaght Ellanyn Fiji --- Fìdi --- Fidxi --- República das Illas Fidxi --- 피지 --- Pʻiji --- Republika Fidžijskoga Otočja --- Republica dagiti Isla ti Fiji --- Republik Kepulauan Fiji --- Fídjieyjar --- Fijieyjar --- Lýðveldið Fídjieyjar --- פיג׳י --- Jamhuri ya Visiwa vya Fiji --- Viti --- Insulae Vitienses --- Insulae Fisienses --- Res Publica Insularum Vitiensium --- Fidži Salu Republika --- Fidžis --- Fidžio Salų Respublika --- Fidzsi-szigetek --- Фиџи --- Република Фиџиски Острови --- Republika Fidžiski Ostrovi --- Tlācatlahtohcāyōtl in Tlālhuāctli Fiyi --- Bidji --- Republiek Fiji-eilanden --- フィジー --- Republikken Fijiøyene --- Republikken Fijiøyane --- Fiji Orollar Respublikasi --- Republika Wysp Fidżi --- Fidźi Dwip-samuh Ganaradźja --- República de Fiji --- República de Fidji --- República das Ilhas Fiji --- Republica Insulelor Fiji --- Phiyi --- Phiyi Wat'akuna Republika --- Witi --- Республика Островов Фиджи --- Respublika Ostrovov Fidzhi --- Fiži --- Fiti --- Fidyïi --- Ködörösêse tî mbênî Fidyïi Zûa --- Fixhi --- Republika e Ishujve Fixhi --- Figgi --- Republika Fidžijských ostrovov --- Republika Fidžijski otoki --- Republika Wyspůw Fidżi --- Република Фиџи Острва --- Fidžisaarten tasavalta --- Republiken Fijiöarna --- Fidzji --- Pidyi --- Republika ng mga Pulo ng Pidyi --- Republika ng Kapuluan ng Pidyi --- Fisi --- Fiji Adaları Cumhuriyeti --- Фіджі --- Республіка Фіджі --- Respublika Fidz︠h︡i --- Cộng hòa Quần đảo Fiji --- Ficiyuäns --- Fijii --- Republik bu iil yu Fiiji --- Fici --- Fėdžis --- Fėdžė Salū Respoblėka --- 斐济 --- Feiji --- Colony of Fiji
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