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In the Research Topic "History of Chemoattractant Research" we will portray some of the key discoveries that helped to transform cell migration research into a global playing field within immunology (and beyond). Early progress had a profound effect on both, academia and industry. Today, numerous academic laboratories are fully engaged in compiling a detailed road map describing the highly complex network of immune and tissue cells that respond to chemoattractants. Industrial research, on the other hand, centers on drugs that interfere with immune cell traffic in inflammatory diseases and cancer. The following series of “short stories” provide personal accounts on key discoveries. The individual molecular discoveries enabled numerous research laboratories worldwide to unravel their significance in steady-state or pathological immune processes. Although ground-breaking in their own right, it is therefore worth emphasizing that rapid progress in chemoattractant research was made possible by many other laboratories who were not directly involved in the original discovery process. Therefore, the authors of this mini-series are discussing their findings in the context of time, place and subsequent progress enabled by their discoveries. It is hoped that a wide readership will find these accounts entertaining as well as educational although those who wish to gain a more detailed knowledge are referred to the many outstanding reviews on chemokines and other chemoattractants.

Homing --- chemokine --- tumour --- cell migration --- Inflammation --- Chemotaxis --- Immunity --- immune surveillance

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This open access book deals with a rich variety of taxis-type cross-diffusive equations. Particularly, it intends to show the key role played by quasi-energy inequality in the derivation of some necessary a priori estimates. This book addresses applied mathematics and all researchers interested in mathematical development of reaction-diffusion theory and its application and can be a basis for a graduate course in applied mathematics.

Boundary value problems. --- Chemotaxis --- Navier-Stokes equations. --- Mathematical models. --- Equations, Navier-Stokes --- Differential equations, Partial --- Fluid dynamics --- Viscous flow --- Chemiotaxis --- Chemotropism --- Biochemistry --- Growth --- Taxes (Biology) --- Boundary conditions (Differential equations) --- Differential equations --- Functions of complex variables --- Mathematical physics --- Initial value problems --- Problemes de contorn --- Quimiotaxi --- Models matemàtics --- Equacions de Navier-Stokes --- Navier-Stokes (Equacions) --- Dinàmica de fluids --- Equacions en derivades parcials --- Models (Matemàtica) --- Models experimentals --- Models teòrics --- Mètodes de simulació --- Anàlisi de sistemes --- Mètode de Montecarlo --- Modelització multiescala --- Models economètrics --- Models lineals (Estadística) --- Models multinivell (Estadística) --- Models no lineals (Estadística) --- Programació (Ordinadors) --- Simulació per ordinador --- Teoria de màquines --- Models biològics --- Bioquímica --- Creixement --- Problemes de valor límit --- Equacions diferencials --- Física matemàtica --- Funcions de variables complexes --- Dispersió (Matemàtica) --- Equacions de Von Kármán --- Problema de Dirichlet --- Problema de Neumann --- Problemes de Riemann-Hilbert --- Problemes de valor inicial --- Reaction-Diffusion --- Haptotaxis --- Navier-Stokes --- Cancer invasion --- Coral fertilization --- Sensity-suppressed motility --- Oncolytic virotherapy --- Foraging scrounging interplay

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Nowadays, assisted reproductive technologies (ARTs) have a pivotal role not only in achieving fertilization in subfertile animals, but they are also involved in the management of the herd, decreasing disease spread and even allowing offspring sex selection. Nonetheless, there are differences between species or even within species that have led researchers worldwide to focus on those differences in order to bypass these specific difficulties. This Special Issue, titled “The Era of Assisted Reproductive Technologies Tailored to the Specific Necessities of Species, Industry and Case Reports” and published in Animals, is composed of 12 original manuscripts and three reviews that offer an overview of current and future ARTs used to improve reproductive outcomes, mainly focused on farm animals, such as horse, pig, bovine, rabbit and ovine species. Thus, the Special Issue covers information from the classical point of view, including comparative studies of different semen extenders, to the most advanced technologies of sperm selection by thermotaxis or chemoattractants, as well as the improvement of sperm features by red light irradiation. The female and embryo contributions to ART outcomes are also covered, for instance, with a study that improves our knowledge by the metabolomic description of follicular fluid composition or the description of better culture conditions of oocytes. In brief, this Special Issue provides a balanced overview of emerging techniques and technologies used to preserve, improve, rescue or even create fertility for domestic farm animals with high economic impact.

IVM --- oocytes --- equine --- metabolomic --- embryo transfer --- reproductive fluids --- pregnancy --- vitrification --- calving --- selection programme --- embryo vitrification --- Gompertz growth curve --- biobanking --- reproductive performance --- stallion sperm --- capacitation --- penicillamine --- thermotaxis --- selection --- BMP15 --- ram --- semen --- semen freezing --- semen extender --- stallions --- semen quality --- fertilizing ability --- Tris --- boar spermatozoa --- perfluorinated compounds --- PFHxS --- PFOS --- spermatozoa toxicology --- glucocorticoid receptor --- gene expression --- RT-qPCR --- seminal plasma --- female genital tract --- rabbit --- spermatozoa --- oocyte --- in vitro fertilization --- extracellular vesicles --- assisted reproductive technologies --- embryo --- oocyte competence --- livestock production --- assisted reproductive technology --- embryo development --- micromanipulation --- in vitro production --- nanoparticles --- liposomes --- exosomes --- cryopreservation --- sheep --- ovary storage --- transport --- in vitro embryo production --- sperm selection --- chemotaxis --- IVF --- IVC --- porcine --- cryopreserved sperm --- sperm–oviduct interaction --- ARTs --- equines --- horse --- sperm --- red light irradiation --- extender --- straw