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The consumption of fruits, vegetables, herbs, spices, etc., is thought to be associated with reduced risk for many human diseases, including cancers. Recently, significant advances have been made in evaluating the efficacy of natural products (compounds from natural sources) against human diseases. The purpose of this Special Issue, “Natural Products and Disease Prevention, Relief and Treatment", was to collect manuscripts concerning natural products for treating human diseases. Consequently, we have collected several high-quality manuscripts that focus on the molecular mechanisms of natural products, including their anti-inflammatory, antioxidative, neuroprotective, cardioprotective, antifibrotic, and anticancer effects, as well as other health beneficial effects across a wide range of human diseases. Overall, this Special Issue is an excellent source for information on promising natural products for future preclinical and clinical research into multiple diseases.

Medicine --- Pharmacology --- Rubi Fructus --- Rubus coreanus --- lipopolysaccharide --- macrophage --- ER stress --- calcium --- chop --- STAT --- cytokine --- nitric oxide --- β-glucan --- anticancer activity --- antioxidant --- anti-inflammatory --- cyclooxygenase --- lipoxygenase --- cauliflower mushroom --- breast cancer --- Spirulina --- tocotrienol --- immunomodulatory --- synergistic --- metastasis --- YG-1 extract --- bronchodilation --- fine particulate matter (PM2.5) --- acute lung injury --- airway inflammation --- pancreatic cancer --- natural product --- traditional medicine --- apoptosis --- angiogenesis --- drug resistance --- inflammation --- interleukin-6 --- sepsis --- Dracocephalum moldavica --- NASH --- lactoferrin --- fibrosis --- hepatocarcinogenesis --- connexin --- brown algae --- Sargassum plagiophyllum --- constipation --- gastrointestinal transit --- gut microbiota --- transepithelial transport --- glaucoma --- herbs --- retinal ganglion cells --- intraocular pressure --- SLC22A12 --- quercetin --- fisetin --- uricosuric activity --- anti-hyperuricemia --- functional food --- transporter --- uric acid --- health promotion --- rooibos tea --- doxorubicin --- mokko lactone --- heart --- Mokko lactone --- Dracocephalum moldavica ethanol extract --- Sparassis crispa --- fisetin and quercetin --- Sargassum plagiophyllum extract