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Despite many years of efforts to reduce the emission of toxic pollutants into the environment, the contamination of air, soils and water by heavy metals and organic xenobiotics is still a serious problem. This has urged many scientists around the world to undertake research that aims to find effective methods of removing pollutants from the environment. Special attention is paid to biological methods, which, thanks to their numerous advantages, meet the expectations of the whole society. As part of the Special Issue "Study of Biodegradation and Bioremediation", in the MDPI journal Processes, several valuable articles have been published, which together form a picture of the current state of advanced research on the effective fight against environmental pollution. These include papers on the biodegradation of petroleum compounds or synthetic dyes by microorganisms or the enzymes they produce. In addition, the Special Issue includes papers on the bioremediation of dangerous heavy metals such as mercury and copper, and the results make a valuable contribution to our current state of knowledge on this topic. A separate and valuable part of this collection of publications are review articles devoted to the remediation of antineoplastic drugs, as well as the hopes and challenges connected with the application of nanotechnology in bioremediation. We are pleased that so many researchers from different parts of the world have submitted their articles on this topic. We are very grateful to them. We hope that readers of this collection will find many interesting ideas and relevant information that will lead to new solutions in the bioremediation and biodegradation of emerging environmental contaminants. Prof. Ewa Kaczorek Dr. Wojciech Smułek.

Biodegradation. --- Bioremediation.

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Fungi-induced stains on paper are one of the most challenging forms of biodeterioration to study and to prevent; this is because they involve living organisms, and the ways in which fungi respond to changes in the environment and modifications of paper are unpredictable. Yet, there is a great desire among those who encounter fungi on documents, manuscripts, or artwork to remove fungi and clean the paper. This experience in most cases is particularly challenging. What are the reasons behind this challenge? This ground-breaking book attempts to answer this question, among others, by exploring the complex interfacial forces between paper, fungi, and their pigmented secretions which result in bio-stains on paper. Black fungi, collectively referred to as Dematiaceous fungi, were used in this study as a subset of pigment-producing fungi species. The focus is on two, under-studied aspects of the fungi infestation of paper, an interface of fungal pigments and paper, and the impact of light on the production of fungi bio-stains. The results of analytical testing included in this book elucidate the synergistic interactions between the environment, biological clocks of the microorganisms, and secretion of fungal pigments to paper. The black fungal pigment formation is explored in-depth in two scenarios: one that is 'natural', when the bio-stains of original artworks have occurred over time by chance, and another, induced by Aspergillus niger, in bio-simulation on known papers in a controlled environment. The findings are intended to provide guidance for preservation strategies, mitigating the biodeterioration of paper, and designing conservation treatment when applicable. The surface of artworks and artifacts is of great aesthetic and artistic importance; conversely, it plays a significant role in governing fungal attachments. In this book, the paper surface is characterized in detail and in correlation with chemical and physical alterations caused by fungal pigmentation. A broad range of analytical instruments was used for surface characterization, such as surface metrology profilometers, a confocal laser scanning microscope, and environmental scanning electron microscope; chemical microanalysis was carried out using X-ray energy dispersive spectroscopy. The novel, three-dimensional characterization of pigmented fungal inclusions and their interaction with paper matrix was studied with micro-X-ray-computed micro-tomography on the synchrotron ESRF. The proposed book is the first to explore the complexity of fungal-paper interactions with the intention to assist professionals working with cultural materials, especially paper-based materials, to make informed decisions when dealing with the fungi infestation of paper.

Biodegradation --- Cultural property --- Protection

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

pollutants --- bioremediation --- biodegradation --- biomineralization --- extremophiles

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Compared to conventional chemical technologies and other similar industrial processes, bioprocesses represent a more sustainable and environmentally-friendly alternative for the production of fuels and platform chemicals. In biorefineries, different kinds of feedstocks, such as biomass or lignocellulosic materials in general, can be used and fermented by microorganisms (e.g., bacteria, fungi, algae), after some pretreatment steps, to produce high added-value metabolites. More recently, wastes, wastewaters and also waste gases have been shown to be suitable for resource recovery or for their bioconversion to (bio)fuels (e.g., ethanol, butanol, hexanol, biodiesel, biohydrogen, biogas) or other commercial products (e.g., biopolymers). In this sense, much effort has also been made to bioconvert greenhouse gases, such as CO2, into useful products. The goal of this Special Issue is to publish both recent innovative research data, as well as review papers on the fermentation of different types of substrates to commercial (bio)fuels and (bio)products, mainly focusing on the bioconversion of pollutants in solid, liquid, or gas phases (wastes, wastewaters, waste gases).

Refuse and refuse disposal --- Biodegradation. --- Bioremediation

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This contribution book collects reviews and original articles from eminent experts working in the interdisciplinary arena of novel drug delivery systems and their uses. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of different drug delivery systems. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. On the other hand, this reference discusses advances in the design, optimization, and adaptation of gene delivery systems for the treatment of cancer, cardiovascular, pulmonary, genetic, and infectious diseases, and considers assessment and review procedures involved in the development of gene-based pharmaceuticals.

Biodegradation --- Toxicology and Pharmaceutical Science --- Pharmaceutical Drug --- Pharmacology --- Health Sciences