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This book is a very provocative addition to the literature on pituitary diseases, it delivers lots of stimulating work and offers rich scientific material for readers in different disciplines. The book provides a detailed update on current diagnostic and therapeutic techniques useful in the management of pituitary diseases. Microsurgical surgery, medical treatment, and radiotherapy has been used in the last decades; however, the prediction of post-medical, postsurgical treatment, and post-radiotherapy treatment is still controversial. The book contents reflect the multidisciplinary approach needed for patients with pituitary diseases with contribution from neurosurgeons, endocrinologists, neurologists, radiologists, ophthalmologists, pathologists, and radiation oncologists. The book focuses on some pituitary diseases especially the most controversial subjects in the medical and surgical treatment such as dedicated surgical technique by huge pituitary adenoma, the management of celiac patients with growth failure, pituitary apoplexy, neuro ophthalmology findings in pituitary disease, and the immunohistochemical studies in pituitary adenomas, moreover there is a special chapter about transoral robotic surgery (TORS) with the da Vinci system.

Pituitary gland --- Diseases. --- Life Sciences --- Neuroscience --- Neuroendocrinology --- Endocrinology

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Melatonin, the pineal neurohormone, is a pleiotropic molecule acting in the center of the integrative molecular mechanisms of the organism, based on interconnections of the regulatory systems: neural, endocrine, immune, and genetic, conveying into the uniqueness of human architecture. This book provides a systematic and updated overview of melatonin biochemical mechanisms of action, pharmacological features, and clinical uses, clutching the subject with complete details of pharmaceutical formulations designed for different routes of administration and different health issues, aiming at optimal melatonin bioavailability when therapeutically delivered. The book addresses a broad range of audiences, from healthcare professionals, medically and pharmaceutically based, to highly profiled medical specialists and biomedical researchers, helping them to expand their knowledge of the physiological and pathological implications of melatonin and its metabolites.

Melatonin. --- Acetylmethoxytryptamine --- Methoxyindolylethylacetamide --- Hormones --- Pineal gland --- Tryptamine --- Secretions --- Medicine --- Neuroendocrinology --- Endocrinology --- Health Sciences

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This book presents an overview of adrenal tumors written by a multidisciplinary team of world experts who provide comprehensive, evidence-based perspective of their topics in this field and current approaches to the management of adrenal tumors. The areas discussed in this book include an overview of adrenal incidentalomas, unusual presentations of adrenal tumors, genetic basis of pheochromocytomas and paragangliomas, pathophysiology, and medical and surgical treatment and approaches to patients with benign and malignant adrenal tumors. Each chapter written by these experts provides clinical evidence, treatment recommendations, and algorithms. Clinical Management of Adrenal Tumors will serve as a valuable resource of current information regarding adrenal tumors for medical students, residents in training, physicians, and researchers.

Tumor antigens. --- Adrenal cortex. --- Adrenal glands --- Hypothalamic-pituitary-adrenal axis --- Antigens --- Tumor markers --- Medicine --- Neuroendocrinology --- Endocrinology --- Health Sciences

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Neurological and psychiatric disorders can occur in endocrine diseases either in the setting of the clinical manifestations of the same (i.e., hyper- or hyposecretion of hormones or peptides from the endocrine glands) or as events secondary to the pathogenetic mechanisms of the endocrinopathy (i.e., autommunity affecting endocrine glands and the brain). Also the medical or surgical treatment of the endocrine disease can sometimes determine the occurrence of neurological or psychiatric abnormalities. Moreover some genetic alterations can lead to syndromes affecting both the endocrine and the nervous system with a variety of possible manifestations. In the last couple of decades a number of associations between dysfunctions of the endocrine system and neurological or psychiatric manifestations have appeared and only in the minority of the cases this link has been fully elucidated. Often the neurological or psychiatric alterations still represent a relevant challenge for clinicians with regard to the management of the patients. The complexity of the topic and the limited availability of laboratory research models for the study of the endocrine system-nervous system cross-interaction are making the scientific progresses intricate and, sometimes, slow. A dedicated focus to such broad and often still obscure topic might help and clarify the current state-of-the-art in the field and direct the goals of future research.

Neuroendocrinology. --- Psychoneuroendocrinology. --- Neuropsychiatry. --- Endocrine System Diseases --- physiopathology. --- Eating Disorders --- Polycystic Ovary Syndrome --- Obesity --- Exercise --- gender identity --- Acromegaly --- Quality of Life --- Cushing Syndrome --- Thyroid Surgery --- Hypogonadism

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Research during the past decade highlights the strong link between appetitive feeding behavior, reward and motivation. Interestingly, stress levels can affect feeding behavior by manipulating hypothalamic circuits and brain dopaminergic reward pathways. Indeed, animals and people will increase or decrease their feeding responses when stressed. In many cases acute stress leads to a decrease in food intake, yet chronic social stressors are associated to increases in caloric intake and adiposity. Interestingly, mood disorders and the treatments used to manage these disorders are also associated with changes in appetite and body weight. These data suggest a strong interaction between the systems that regulate feeding and metabolism and those that regulate mood. This Research Topic aims to illustrate how hormonal mechanisms regulate the nexus between feeding behavior and stress. It focuses on the hormonal regulation of hypothalamic circuits and/or brain dopaminergic systems, as the potential sites controlling the converging pathways between feeding behavior and stress.

Neuroendocrinology. --- Paraneurons. --- Stress (Physiology) --- Obesity --- Dopamine. --- Ghrelin. --- Leptin. --- Neuroscience --- Human Anatomy & Physiology --- Health & Biological Sciences --- Endocrine aspects. --- Hormonal aspects of physiological stress --- Endocrinology --- Neuroendocrine cells --- Neurons --- Chromaffin cells --- Neurology --- Neurohormones --- Adiposity --- Corpulence --- Fatness --- Overweight --- Body weight --- Metabolism --- Nutrition disorders --- Ob protein --- Hormones --- Motilin-related peptide --- Gastrointestinal hormones --- Peptide hormones --- Biogenic amines --- Bromocriptine --- Catecholamines --- Neurotransmitters --- Hormonal aspects --- Disorders --- stress --- Dopamine --- Ghrelin --- Leptin --- Seasonal regulation --- feeding --- HPA axis --- Hypothalamus --- circadian rhythms