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Deze derde editie van het Handboek Psychofarmacotherapie bevat een grondige herziening van de bestaande data en aanvulling met meer recente wetenschappelijke gegevens en aanbevelingen. Het accent ligt op de farmacologische aspecten van de diverse aangehaalde farmaca en minder op de theoretische achtergrond van de ziektebeelden. Het gebruik van overzichtelijke schema's, beslissingsbomen en overzichtelijke tabellen werd aangemoedigd voor deze nieuwe editie. Naast evidence based literatuur, wordt ook gekeken naar eigen opinies of standpunten berustend op individuele ervaring (expert opinion). Er werden een aantal nieuwe hoofdstukken ingevoegd zoals de farmacologische benadering van ADHD en autisme, educatie in correct psychofarmacagebruik, ethiek van het voorschrijven, de toekomstperspectieven van de farmacogenetica, het interpreteren van onderzoek- en studieresultaten en een kort historisch overzicht van deze nog relatief jonge discipline.

Psychofarmaca. --- farmacologie --- Pharmacology. Therapy --- psychofarmaca --- Psychofarmaca --- Psychotropic drugs --- Handbooks, manuals, etc. --- Psychotherapy --- Farmacologie. Therapie --- Psychotropic Drugs --- psychiatrie --- psychofarmacotherapie --- 607.1 --- 612.8 --- gezondheidszorg --- 615 --- Geneesmiddelen --- Psychiatrie --- Farmacologie --- Psychotherapie --- therapeutic use --- Lichamelijke behandelingsmethoden --- Farmacie - Geneesmiddelen --- PHL-Healthcare 12 --- Schizofrenie --- Psychosen --- Stemmingsstoornissen --- Angststoornissen --- Slaapproblemen --- Agressiviteit --- Somatoforme stoornissen --- Eetstoornissen --- Zwangerschap --- Lactatie --- Seksualiteit --- Persoonlijkheidsstoornissen --- Psychofarmacon --- Psychose --- Stemmingsstoornis --- Angststoornis --- Slaapprobleem --- Somatoforme stoornis --- Eetstoornis --- Persoonlijkheidsstoornis --- Farmacotherapie --- Psychiatry

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Continuous rigorous research in basic neurosciences and in clinical studies has enormously increased our knowledge of the neurobiological basis of mental functions and of the neuronal dysfunctions underlying such diseases as schizophrenia, depression, attention deficit disorder, and Parkinson's disease. A transmitter system does not work in isolation, it interacts with other transmitters and the balance between several transmitter determines the outcome, either physiological or pathological. Such a critical balance exists between dopamine and glutamate, which in many brain areas play functionally opposing roles. In Dopamine and Glutamate in Psychiatric Disorders, a panel of neurochemists, pharmacologists, experimental psychologists, and clinicians summarizes our current understanding of the interactive role of dopamine and glutamate in psychiatric diseases and from that develops novel therapeutic strategies and possibilities for the future. Among the new ideas presented are hypotheses on the role of dopamine and glutamate in aggression, the glutamate system in anxiety disorders, glutamate and neurodegeneration, on the origin, progression, and cognitive aspects of Parkinson's disease. Additional chapters offer illuminating insights into a variety of psychiatric diseases, including attention deficit hyperactivity disorder, stress, aggression, addiction, schizophrenia, depression, social phobias, dementias, bulimia, and neurodegenerative diseases like Parkinson's and Alzheimer's diseases. Each chapter summarizes the prevalence and symptoms of the disease and explains the involvement of dopamine and/or glutamate systems using the newer molecular approaches such as transgenic knockout or knockin mice and recent brain imaging techniques. The authors also offer a critical selection and evaluation of relevant literature and a description of future directions for new therapy development. Path-breaking and insightful, Dopamine and Glutamate in Psychiatric Disorders offers behavioral pharmacologists, neurobiologists, and clinicians an enlightening review of the neurobiological basis and treatment strategies of today's most important psychiatric and neurological diseases.

Medicine & Public Health. --- Psychiatry. --- Medicine. --- Médecine --- Psychiatrie --- Antidepressive Agents -- pharmacology. --- Antipsychotic Agents -- pharmacology. --- Dopamine -- Pathophysiology. --- Glutamate -- Pathophysiology. --- Mental Disorders -- drug therapy. --- Mental Disorders -- etiology. --- Nervous System Diseases -- drug therapy. --- Nervous System Diseases -- etiology. --- Neuropsychiatry. --- Neurotransmitter receptors. --- Neuropsychiatry --- Dopamine --- Glutamate --- Neurotransmitter receptors --- Tranquilizing Agents --- Receptors, Catecholamine --- Amino Acids, Dicarboxylic --- Psychiatry and Psychology --- Psychotropic Drugs --- Excitatory Amino Acids --- Receptors, Amino Acid --- Diseases --- Amino Acids, Acidic --- Catecholamines --- Central Nervous System Agents --- Amino Acids --- Receptors, Biogenic Amine --- Central Nervous System Depressants --- Biogenic Monoamines --- Receptors, Neurotransmitter --- Receptors, G-Protein-Coupled --- Amines --- Amino Acids, Peptides, and Proteins --- Receptors, Cell Surface --- Biogenic Amines --- Organic Chemicals --- Physiological Effects of Drugs --- Therapeutic Uses --- Pharmacologic Actions --- Membrane Proteins --- Chemicals and Drugs --- Proteins --- Chemical Actions and Uses --- Antidepressive Agents --- Antipsychotic Agents --- Mental Disorders --- Glutamic Acid --- Receptors, Dopamine --- Receptors, Glutamate --- Nervous System Diseases --- Medicine --- Psychiatry --- Health & Biological Sciences --- Neurology --- Psychiatry - General --- Pathophysiology --- Glutamic acid --- Pathophysiology. --- Behavioral neurology --- Medicine and psychology --- Mental health --- Psychology, Pathological --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Excitatory amino acids --- Umami (Taste) --- Biogenic amines --- Bromocriptine --- Neurotransmitters --- Biological psychiatry --- Cell receptors --- Hormone receptors --- Neural receptors