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This volume brings some of the worlds best investigators to describe recent advances in both the scientific and clinical aspects of malaria, and bridges between the two. The opening chapters discuss antimalarials and resistance to them in Africa and Asia. Then there are reviews of the different clinical manifestations of malaria, ranging from uncomplicated infections to severe disease and its complications. This section is followed by detailed reviews of what the new ˜omics' offer to investigators of Plasmodium biology and is completed by descriptions of advances in understanding the biology of Plasmodium in the mosquito. If this volume attracts new students and provokes existing investigators to explore new directions, then it will have achieved much of what it has set out to do.

General parasitology --- parasitologie --- malaria

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This book on Biomphalaria Snails and Larval Trematodes  presents up to date information on the interactions of these snails and their trematode parasites, particularly on Schistosoma spp. larvae. Snails of the genus Biomphalaria are of significant medical importance since several species in this genus are obligate intermediate hosts of the human blood fluke S. mansoni, the causative agent of hepatosplenic schistosomiasis. In addition to the impact of Biomphalaria spp. on public health, these snails are also interesting models for the study of other topics such as population biology, including genetics and demography, proteomics, invertebrate immunobiology, mating systems, biogeography, among others. A purpose of this book is to provide an overview of the recent advances in Biomphalaria spp.-larval trematode interactions, especially in Biomphalaria-schistosome systems. Emphasis is placed on gaps in our knowledge that need to be filled to gain a better understanding of the relationships in these host-parasite systems. This may be critical to obtain a better understanding of our knowledge of the transmission of schistosomiasis and other snail-borne parasitic diseases. The book, Biomphalaria Snails and Larval Trematodes  is an ideal volume for researchers and advanced students interested in modern aspects of parasitology , malacology and public health.

General parasitology --- Human biochemistry --- Infectious diseases. Communicable diseases --- medische biochemie --- biochemie --- parasitologie --- besmettelijke ziekten

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Without a doubt the recently accelerating globalization supports the import of agents of disease into countries where they never had been or where they had long since been eradicated, leading to a false sense of living on a safe island.  These newly imported or reintroduced diseases - called emerging diseases  - may lead to severe outbreaks in cases where the countries are not prepared to combat them, or in cases where viruses are introduced that cannot be controlled by medications or vaccines.  Arthropods are well known vectors for the spread of diseases. Thus their invasion from foreign countries and their spreading close to human dwellings must be blocked everywhere (in donor and receptor countries) using safe and effective measures.  This book presents reviews on examples of such arthropod-borne emerging diseases that lurk on the fringes of our crowded megacities. The following topics show that there is an ongoing invasion of potential vectors and that control measures must be used now in order to avoid disastrous outbreaks of mass diseases.

General parasitology --- Zoology --- Hygiene. Public health. Protection --- Veterinary medicine --- diergeneeskunde --- preventieve gezondheidszorg --- parasitologie --- gezondheidspromotie --- zoölogie

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will follow

General parasitology --- Immunology. Immunopathology --- Medical microbiology, virology, parasitology --- Neuropathology --- immunologie --- neurologie --- parasitologie --- virologie

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Nature helps... of course at first itself by developing measures that give bacteria, fungi, plants and animals a chance to be successful in their struggle for life. As a latecomer on Earth, Homo sapiens was gifted with some droplets of the divine spirit of recognition and thus became able to observe, to analyse and recombine skills of other living beings and to use them for his overwhelming career over the last 10,000 years. Of course fungi, plants, animals and even bacteria were primarily used by mankind as food or as lifestyle products such as beer, but soon it became clear that there was much more potential hidden in these organisms and that they could be used for other purposes, too. Extracts of plants and fungi were recognized as powerful remedies, as medicines, as insecticides or acarizides, as repellents against parasites or even as weapons, e.g. when poisonous compounds from frogs or plants were applied to arrowheads. Over the last 110 years the pharmaceutical industry has often simulated nature by analyzing complex organic substances taken from living organisms and then producing by synthesis absolutely pure compounds, which mostly consisted of only one single active substance. These products had the advantage of acting against precisely one target and thus produced fewer possible side effects than the complex plant extracts. However, the more serious side effect was that disease agents could develop resistances to pure medicinal products much more easily. Thus after 70 years of excellent prospects for chemotherapy, some dark clouds appeared and quickly gathered, so that several therapeutic remedies now no longer work. Therefore in many countries - especially in those where the pure chemotherapeutics are too expensive for the poor population - the cry back to nature  is becoming louder and louder. This has led to an enormous increase of studies that again use natural extracts as remedies in the fight against diseases. The present book summarizes examples of promising aspects in a broad spectrum of applications and shows how extracts derived from bacteria, marine organisms, plants or even animals may help to treat infectious diseases, how such organisms may keep away parasites and pests from the bodies of plants or animals, including humans, and how they can be used directly to aid in diagnosis, promote wound healing and even to help catch criminals. These 15 chapters offer not only basic research on these different fields, but also show how useful and effective products can be developed from research.

General parasitology --- General microbiology --- General ecology and biosociology --- Zoology --- microbiologie --- parasitologie --- ecologie --- zoölogie