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Book
The Statistical Analysis of Functional MRI Data
Authors: ---
ISBN: 9780387781914 Year: 2008 Publisher: New York, NY Springer-Verlag New York

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Abstract

One of the most intriguing questions facing modern science is the inner workings of the human brain. Functional magnetic resonance imaging (fMRI) is a powerful tool used to study the human brain in action. The data produced from mapping the active processes within the brain present many challenges to statisticians, computer scientists, engineers and other data analysts, due to their complex structure and the ever-increasing sophistication of the scientific questions being posed by researchers. This book represents the first in-depth discussion of statistical methodology, which it couples with an introduction to the scientific background needed to understand the data. Starting from the basic science - where fMRI data come from, why they are so complicated, and the role statistics can play in designing and interpreting experiments - the book gives a detailed survey of the numerous methods that have been applied in the last fifteen years. The analysis of fMRI data features many of the major issues of concern in modern statistics, such as high dimensionality, multiple testing, and visualization. The array of techniques examined in the book ranges from the simple two-sample t-test and the general linear model to hierarchical spatiotemporal models, multivariate methods such as principal components analysis, and Bayesian approaches as they have been used in fMRI. Software, including descriptions of the most popular freeware packages and their capabilities, is also discussed. This book offers researchers who are interested in the analysis of fMRI data a detailed discussion from a statistical perspective that covers the entire process from data collection to the graphical presentation of results. The book is a valuable resource for statisticians who want to learn more about this growing field, and for neuroscientists who want to learn more about how their data can be analyzed. Nicole A. Lazar is Professor of Statistics at the University of Georgia and affiliated faculty of the Center for Health Statistics, University of Illinois at Chicago. She is a prominent researcher in this area, a contributor to the FIASCO software for fMRI data analysis, and heads an fMRI statistics research group at the University of Georgia.

Totally accessible MRI : a user's guide to principles, technology, and applications
Author:
ISBN: 9780387488967 0387488952 9780387488950 0387488960 Year: 2008 Publisher: New York ; London : Springer,

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This practical guide offers a lucid introduction to the principles of MRI physics. The author, recognized in the imaging community for his exceptional teaching methods and lectures, has written an easy to understand text. Each chapter explains the "why" and "how" behind MRI. Readers will understand how altering MRI parameters will have many different consequences for image quality and the speed in which images are generated. Practical topics, selected for their value to clinical practice, include progressive changes in key MRI parameters, imaging time, and signal to noise ratio. A wealth of high quality illustrations, complemented by concise text, enables readers to gain a thorough understanding of the subject without requiring prior in-depth knowledge.


Book
MRI from A to Z : A Definitive Guide for Medical Professionals
Authors: ---
ISBN: 9781849961356 9781849961349 Year: 2011 Publisher: London Springer London

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This second edition of Gary Liney's MRI from A-Z, much expanded from the first edition, is both a reflection of and an apt companion for the dramatic growth in the field of MRI. The MRI trainee and the extensively experienced MRI practitioner alike will find this A-Z of the field, with 1,300 entries and 100 illustrations, to be an indispensable reference tool. Providing the reader with concise, clear and eloquent definitions of MRI terminology, this book is both highly practical and a pleasure to read. Gary Liney, PhD is the Principal Physicist for Oncology Imaging and Radiotherapy Physics at the Queen's Centre for Oncology, Castle Hill Hospital, Cottingham, UK.


Book
Diffusion MRI Outside the Brain
Authors: --- --- ---
ISBN: 9783642210525 Year: 2012 Publisher: Berlin, Heidelberg Springer Berlin Heidelberg

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Diffusion MRI allows indirect estimation of the perfusion and cellularity of normal and abnormal tissues and has conventionally been used in the brain in order to evaluate ischemia, tumors, and other conditions. Application in other parts of the body has been hampered by the occurrence of motion and susceptibility artifacts. However, recent advances in MR technology are overcoming these hurdles, allowing the use of diffusion MRI in organs outside the brain. In this book, the authors present cases drawn from daily clinical practice to illustrate the role of diffusion sequences, along with other morphological and functional MRI information, in the work-up of a variety of frequently encountered oncological and non-oncological diseases. Breast, musculoskeletal, whole-body, and other applications are covered in detail, with careful explanation of the pros and cons of diffusion MRI in each circumstance. Quantification and post-processing are discussed, and advice is provided on how to acquire state of the art images, and avoid artifacts, when using 1.5- and 3-T magnets. Applications likely to emerge in the near future, such as for screening, are also reviewed. The practical approach adopted by the authors, combined with the wealth of high-quality illustrations, ensures that this book will be of great value to practitioners.


Book
MRI in Clinical Practice
Authors: ---
ISBN: 9781846281624 Year: 2006 Publisher: London Springer-Verlag London Ltd

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MRI in Clinical Practice provides an easily accessible source of reference material to supplement existing texts, distilling a wide breadth of theoretical and practical information into a pocket-sized manual. The book covers the basic Physics behind MRI, quality assurance, up-to-date safety guidelines and a useful gallery of image artefacts. Part of the book focuses on the specific areas of the body in which MRI is currently exploited, describing how MRI is performed in practice. In each of these sections, a common theme is followed with illustrations of MR images acquired with clinically relevant settings and typical imaging protocols are also explicitly stated. Additional information is provided which includes a subjective view of the strengths and weaknesses of MRI in comparison to other imaging modalities. As well as covering routine clinical techniques, the latest advanced methods (e.g. spectroscopy, fMRI, diffusion, high field MRI) are discussed and placed into the context of clinical application. While primarily useful to the MRI practitioner or trainee, MRI in Clinical Practice will be useful for a larger audience including post-graduate students, physicists, radiologists and technologists.


Book
Liver MRI
Authors: ---
ISBN: 9783540682394 Year: 2007 Publisher: Berlin, Heidelberg Springer-Verlag Berlin Heidelberg

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In March 1973, a short paper was published in Nature, entitled žImage formation by induced local int- action; examples employing nuclear magnetic resonance. The author was Paul C. Lauterbur, a Prof- sor of Chemistry at the State University of New York at Stony Brook. In this seminal manuscript the - thor described a new imaging technique which moved the single dimension of NMR spectroscopy to the dual dimension of spatial orientation, thereby resulting in the foundation of modern magnetic re- nance (MR) imaging. Over the ensuing years, MR imaging has assumed an increasingly important role in clinical imaging. It distinguishes itself from other imaging modalities, such as ultrasound (US) or computed tomography (CT), by the unique ability to visualize specific tissue components in a non-- vasive manner. In the earlier days, diagnostic MR imaging was limited to cerebral and musculoskeletal diseases. - aging of other areas which are more prone to movement through breathing (abdominal) or pulsation motions (cardiac) became available more recently, with the introduction of faster sequences and the - velopment of more dedicated MR imaging coils. Currently, liver MRI is considered the cornerstone of abdominal imaging. In most centers, however, liver MRI is still employed largely as a problem solving modality, when US and CT have provided an unsatisfactory outcome.

How does MRI work? : an introduction to the physics and function of magnetic resonance imaging
Authors: --- ---
ISBN: 9783540300670 3540300678 9783540378457 9786610620593 3540378456 1280620595 1429420995 Year: 2006 Publisher: Berlin, Germany : Springer,

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Abstract

It is with great pleasure that we present this completely revised English e- tion of our book How Does MRI Work? An Introduction to the Physics and Function of Magnetic Resonance Imaging only two years afer publication of the frst English edition. We are particularly pleased that our introductory textbook met with great approval in the English-speaking world and not just in the German-speaking countries. Tis success has been an enormous - centive for us to further improve and update the text. For this reason, we are now presenting a second edition. All chapters have been thoroughly revised and updated to include the latest developments in the ever-changing feld of MRI technology. In particular, the chapter on cardiovascular imaging has been improved and expanded. We gratefully acknowledge the contribution of Daniel Nanz, PhD, the author of this chapter. Moreover, two completely new chapters have been added: “Fat Suppression Techniques” and “High- Field Clinical MR Imaging”. Notwithstanding these additions, the intended readership of our book remains the same: it is not a book for MR specialists or MR physicists but for our students, residents, and technologists, in short, all those who are interested in MRI and are looking for an easy-to-understand introduction to the technical basis of this imaging modality at the beginning of their MRI training. Te second English edition presented here corresponds to and appears together with the completely revised ffh German edition.

Keywords

Magnetic Resonance Imaging --- Magnetic resonance imaging --- Imagerie par résonance magnétique --- 608.5 --- Medische beeldvorming --- MRI --- Radiologie --- Magnetic resonance imaging. --- Magnetic Resonance Imaging. --- Diagnostic Imaging --- Tomography --- Diagnostic Techniques and Procedures --- Diagnosis --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Physics --- Medicine --- Physical Sciences & Mathematics --- Health & Biological Sciences --- Electricity & Magnetism --- Radiology, MRI, Ultrasonography & Medical Physics --- Clinical magnetic resonance imaging --- Diagnostic magnetic resonance imaging --- Functional magnetic resonance imaging --- Imaging, Magnetic resonance --- Medical magnetic resonance imaging --- MR imaging --- MRI (Magnetic resonance imaging) --- NMR imaging --- Nuclear magnetic resonance --- Nuclear magnetic resonance imaging --- Diagnostic use --- Medicine. --- Radiology. --- Condensed matter. --- Biophysics. --- Biological physics. --- Medicine & Public Health. --- Imaging / Radiology. --- Condensed Matter Physics. --- Biophysics and Biological Physics. --- Cross-sectional imaging --- Diagnostic imaging --- Radiology, Medical. --- Biological and Medical Physics, Biophysics. --- Clinical radiology --- Radiology, Medical --- Radiology (Medicine) --- Medical physics --- Biological physics --- Biology --- Medical sciences --- Condensed materials --- Condensed media --- Condensed phase --- Materials, Condensed --- Media, Condensed --- Phase, Condensed --- Liquids --- Matter --- Solids --- Radiological physics --- Radiation


Book
Neurovascular Imaging
Authors: ---
ISBN: 9781848821347 9781848821330 Year: 2010 Publisher: London Springer London

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The comparison of MR images and cadaver microangiograms of the basal perforating arteries is crucial for understanding the courses and supply areas of these vessels and in turn, for diagnosing pathologies in this region. Divided into three sections- normal anatomy of brain vessels; neurovascular imaging in pathology; and anatomy and imaging of spinal vessels- Neurovascular Imaging contains a rich collection of images to teach the reader how to interpret MR images of the brain vessels and spinal vessels, and how to identify pathologies. Written and edited by a group of highly acclaimed experts in the field, Neurovascular Imaging is an authoritative account of the interpretation of MR images of the brain vessels and spinal vessels, and is a valuable addition to the library of the diagnostic radiologist.


Book
Dynamic Contrast-Enhanced Magnetic Resonance Imaging in Oncology
Authors: --- --- ---
ISBN: 9783540264200 Year: 2005 Publisher: Berlin, Heidelberg Springer-Verlag Berlin Heidelberg

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Dynamic contrast-enhanced MRI is now established as the methodology of choice for the assessment of tumor microcirculation in vivo. This is assisting clinical practitioners in the management of patients with solid tumors and is finding prominence in the assessment of tumor treatments, including anti-angiogenics, chemotherapy, and radiotherapy. In this book, targeted at both clinical practitioners and basic scientists, the principles of the methods, their practical implementation, and their application to specific tumor types are discussed by the leading authorities in the field today. The book will serve as an invaluable single-volume reference covering all the latest developments in contrast-enhanced oncological MRI.


Book
MRI of the Liver
Authors: --- --- ---
ISBN: 9788847004696 Year: 2006 Publisher: Milano Springer-Verlag Italia

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Due to the latest developments in magnetic resonance imaging for the evaluation of liver pathology, a second, completely revised and enlarged edition of this book was felt necessary - despite only three years having elapsed since the first edition. All chapters from the first edition have been revised and enriched with additional illustrations and information. New chapters have been added covering important and highly relevant topics, among which imaging of pseudolesions, imaging of neoplastic diseases in pediatric subjects, imaging of bile ducts, MR angiography and imaging pre and post liver transplantation. Particular attention has been paid to the differential use of contrast agents with emphasis placed on the authors' broad experience of MR imaging of focal liver lesions using different contrast agents. The diverse mechanisms of action of all MR contrast agents applicable for liver imaging are explained in detail and comparative examples are provided. As was the case with the first edition, this book will prove invaluable to radiologists wishing to further expand or consolidate their routine approach to MR imaging of the liver.

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