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A major challenge in the modeling and simulation of tumor growth is the mathematical description of living matter, which is far more complex than a mathematical description of inert matter. One critical piece of this challenge is creating multiscale models that take into account subcellular, cellular, and macroscopic levels of cancer. The complexity of these different levels requires the development of new mathematical methods and ideas, which are examined in this work. Written by first-rate researchers in the field of mathematical biology, this collection of selected chapters offers a comprehensive overview of state-of-the-art mathematical methods and tools for modeling and analyzing cancer phenomena. Topics covered include: * Genetic and epigenetic pathways to colon cancer * A game theoretical perspective on the somatic evolution of cancer * Nonlinear modeling and simulation of tumor growth * Tumor cords and their response to anticancer agents * Modeling diffusely invading brain tumors * Multiphase models of tumor growth * Mathematical modeling of breast carcinogenesis * Predictive models in tumor immunology * Multiscale modeling of solid tumor growth Selected Topics in Cancer Modeling is an excellent reference for researchers, practitioners, and graduate students in applied mathematics, mathematical biology, and related fields. The book has an overall aim of quantitative, predictive mathematical modeling of solid tumor growth at all scales, from genetics all the way through to treatment therapy for patients.

Mathematics. --- Oncology. --- Applications of Mathematics. --- Physiological, Cellular and Medical Topics. --- Mathematical Biology in General. --- Mathematical Modeling and Industrial Mathematics. --- Biology --- Physiology --- Mathématiques --- Cancérologie --- Tumors --Growth --Computer simulation. --- Tumors --Growth --Mathematical models. --- Tumors --- Diseases --- Computing Methodologies --- Investigative Techniques --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Information Science --- Models, Theoretical --- Computer Simulation --- Neoplasms --- Medicine --- Health & Biological Sciences --- Oncology --- Growth --- Mathematical models --- Computer simulation --- Computer simulation. --- Mathematical models. --- Tumours --- Health informatics. --- Applied mathematics. --- Engineering mathematics. --- Biomathematics. --- Health Informatics. --- Mathematical and Computational Biology. --- Pathology --- Cysts (Pathology) --- Oncology  . --- Medical records --- Data processing. --- Math --- Science --- Animal physiology --- Animals --- Anatomy --- EHR systems --- EHR technology --- EHRs (Electronic health records) --- Electronic health records --- Electronic medical records --- EMR systems --- EMRs (Electronic medical records) --- Information storage and retrieval systems --- Medical care --- Engineering --- Engineering analysis --- Mathematical analysis --- Mathematics --- Clinical informatics --- Health informatics --- Medical information science --- Information science --- Models, Mathematical --- Simulation methods --- Data processing

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When speaking about eBusiness as applied to the healthcare market two questions arise immediately. Firstly, what is eBusiness? Secondly, why is eBusiness in healthcare different from eBusiness in other sectors? Within the arena of eBusiness in healthcare, the focus is on purchasing and selling online as the most advanced application. In this book, the Authors consider both the perspective of the healthcare providers and that of the suppliers, showing the interdependencies between the two and developing concepts for a new synergistic cooperation. eBusiness in Healthcare raises awareness of and interest in electronically mediated business processes in healthcare to a large audience including healthcare informaticians, medical business managers, clinicians, pharmacists and scientists. By taking an international approach to the topic the authors demonstrate the many similarities of eBusiness problems and their solutions among different countries which permits analysis of the differences that are often defined by the national healthcare systems and their rules. Case studies from healthcare institutions and from suppliers in the US, the UK and Germany will illustrate the achievements, barriers and future plans, thus enabling newcomers to learn from previous experience. Clinicians will gain significant insight by this book which demonstrates the interconnection between patient care processes and management issues at the level of medical supplies. The book also makes a plea for a multidisciplinary effort, to enable the right product to be procured for the right patient. As a rather new discipline, eBusiness in healthcare needs further scientific backing. Against this background, this book will not only provide answers but will also raise questions for future research. Managing change and innovation and establishing the critical mass for eBusiness in healthcare is a major undertaking. The aim of this book is to support this process.

Medical supplies --- Hospital purchasing --- Electronic commerce. --- Purchasing --- Data processing. --- Cybercommerce --- E-business --- E-commerce --- E-tailing --- eBusiness --- eCommerce --- Electronic business --- Internet commerce --- Internet retailing --- Online commerce --- Web retailing --- Commerce --- Information superhighway --- Hospitals --- Hospital supplies --- Medical products --- Medicine --- Supplies, Medical --- Health products --- Materials management --- Equipment and supplies --- Medical records --- Industrial procurement. --- Health Informatics. --- Procurement. --- Buyer-supplier relations --- Buying, Industrial --- Industrial buying --- Industrial equipment --- Industrial purchasing --- Procurement, Industrial --- Purchasing, Industrial --- Supplier-buyer relations --- Industrial management --- EHR systems --- EHR technology --- EHRs (Electronic health records) --- Electronic health records --- Electronic medical records --- EMR systems --- EMRs (Electronic medical records) --- Information storage and retrieval systems --- Medical care --- Health informatics. --- Clinical informatics --- Health informatics --- Medical information science --- Information science --- Data processing

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Several theories consider the brain to be a network of neurons that process perception with simple activation functions. Real neurons, however, are far more intricate.Through reviews of literature and results from original experiments, Neural Cell Behavior and Fuzzy Logic offers a comprehensive look at these complex systems, supplying trustworthy evidence that neurons can predict the consequences of input signals and transiently change their own excitability to suit. The book also examines how fuzzy logic, the computing of perceptions, can be used to provide a theoretical description of real neuron behavior, and as a model for the "logic" the brain uses to describe environments and make decisions. This book includes sections for general and advanced readers, and will be particularly useful to neuroscience students, academics and researchers as well as to mathematicians and theoretical physicists. About the authors: Uziel Sandler is a professor in the Department of Applied Mathematics at Jerusalem College of Technology in Israel. Dr. Sandler is an expert in nonlinear properties and critical behavior of condensed matter, evolutionary computations, and fuzzy sets theory. He has published two books and more than 70 academic articles in scientific journals, and is a member in several worldwide committees in the aforementioned fields. Professor Lev E.Tsitolovsky is a senior researcher in the Life Science Department of Bar-Ilan University in Israel. He is a renowned expert in the fields of thorough mechanisms of learning, memory , and motivation , and has published over 100 scientific papers and reviews on these topics. Recently, his discovery of excitable membrane plasticity anticipated modern development in this area.

Biomedicine. --- Neurosciences. --- Computer Appl. in Life Sciences. --- Neurobiology. --- Neurology. --- Medicine. --- Biology --- Médecine --- Neurosciences --- Neurologie --- Biologie --- Neurobiologie --- Data processing. --- Informatique --- Fuzzy logic. --- Fuzzy Logic --- Models, Neurological --- Neurons --- Neural Networks (Computer) --- Models, Biological --- Pattern Recognition, Automated --- Artificial Intelligence --- Nervous System --- Cells --- Models, Theoretical --- Mathematical Concepts --- Logic --- Anatomy --- Information Science --- Computing Methodologies --- Phenomena and Processes --- Philosophy --- Investigative Techniques --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Humanities --- Neuroscience --- Neurology --- Medicine --- Human Anatomy & Physiology --- Health & Biological Sciences --- Neurobiology --- Mathematics. --- Nonlinear logic --- Bioinformatics. --- Computational biology. --- Fuzzy mathematics --- Logic, Symbolic and mathematical --- Fuzzy systems --- Nervous system --- Neuropsychiatry --- Neural sciences --- Neurological sciences --- Medical sciences --- Diseases --- Bioinformatics . --- Computational biology . --- Neurology . --- Bioinformatics --- Bio-informatics --- Biological informatics --- Information science --- Computational biology --- Systems biology --- Data processing