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Brain metastases are the most dreaded complication of systemic cancer, affecting approximately 170,000 people a year, a far greater incidence than primary brain tumors. Advances in modern chemotherapy have led to an improved control of system cancers, often with agents that poorly penetrate the central nervous system, resulting in an increasing incidence of brain metastases. Traditional chemotherapy has had little impact on brain metastases. The main therapeutic option is radiation therapy, and in a small number of patients - surgery. However, refinements in all of these treatments offer some positive outcomes and an increased ability to stratify patients based on certain criteria. This book will bring current information on the presentation and management of patients with brain metastases, providing available data, giving guidelines that can be applied in day to day practice, updated information for neuro-surgeons, radiation oncologists, medical oncologists, and neuro-oncologists, as well as an overview for physicians in training. "Brain metastases are one of the most devasting consequences of cancer. This text addresses the epidemiology, pathophysiology, imaging, and management of this complication. Experts in the field cover a broad array of relevant topics highlighting the challenges and current therapeutic strategies." Steven T. Rosen, M.D. Series Editor.
Brain --- Metastasis. --- Cancer. --- Cancer --- Cancer metastasis --- Dissemination of cancer --- Metastases --- Metastatic cancer --- Neoplasm metastasis --- Spread of cancer --- Tumor dissemination --- Tumor metastasis --- Tumor spread --- Pathology --- Cancer invasiveness --- Cancer of unknown primary origin --- Dissemination --- Metastasis --- Oncology . --- Surgical oncology. --- Neurosurgery. --- Oncology. --- Surgical Oncology. --- Nerves --- Neurosurgery --- Oncologic surgery --- Oncological surgery --- Surgical oncology --- Tumors --- Surgery --- Excision --- Treatment --- Nervous system --- Cancer Therapy. --- Treatment. --- Surgery. --- Cancer therapy --- Cancer treatment --- Therapy --- Brain Neoplasms --- Cerveau --- Métastases --- secondary. --- EPUB-LIV-FT LIVMEDEC LIVSANTE SPRINGER-B
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Distributed software systems are becoming evermore prevalent, and we increasingly desire them to operate in heterogeneous, dynamic, and open environments. Service-oriented computing (SOC) has emerged over recent years as a successful approach for building and maintaining such systems. However, as the environments in which we require systems to operate become more complex, we require software components to have increasing degrees of flexibility, autonomy, and intelligence. Agent-based systems naturally complement SOC by offering the intelligence and reasoning capabilities that are needed. The integration of agents and SOC is a broad and active research area. This book is a collection of chapters from experts in the field, that gives an overview of the state-of-the-art in the main areas of current research, and identifies likely future directions. Researchers, students and practitioners will find this book a useful insight into the current state-of-the-art. The book also includes a general introduction the basic notions of SOC for readers who are unfamiliar with the approach.
Business policy --- Business management --- Computer science --- Programming --- Computer architecture. Operating systems --- Information systems --- Artificial intelligence. Robotics. Simulation. Graphics --- Computer. Automation --- ICT (informatie- en communicatietechnieken) --- MIS (management informatie systeem) --- computers --- informatica --- programmeren (informatica) --- organisatiecultuur --- informatietechnologie --- software engineering --- KI (kunstmatige intelligentie) --- informatica management --- computerkunde --- Web services --- 681.3*D211 --- 681.3*D22 --- 681.3*D47 --- 681.3*H34 --- 681.3*H35 --- 681.3*H35 On-line information services: data bank sharing --- On-line information services: data bank sharing --- 681.3*H34 Systems and software: current awareness systems; selective dissemination of information; SDI; information networks; question-answering (fact retrieval) systems (Information storage and retrieval) --- Systems and software: current awareness systems; selective dissemination of information; SDI; information networks; question-answering (fact retrieval) systems (Information storage and retrieval) --- 681.3*D47 Organization and design: batch processing systems; distributed systems; hierarchical design; interactive systems; real-time systems (Operating systems) --- Organization and design: batch processing systems; distributed systems; hierarchical design; interactive systems; real-time systems (Operating systems) --- 681.3*D22 Tools and techniques: decision tables; flow charts; modules and interfaces; programmer workbench; software libraries; structured programming; top-down programming; user interfaces (Software engineering) --- Tools and techniques: decision tables; flow charts; modules and interfaces; programmer workbench; software libraries; structured programming; top-down programming; user interfaces (Software engineering) --- Application software --- Cloud computing --- Software architectures: data abstractio, domain-specific architectures, information hiding, languages (e.g. description, interconnection, definition), patterns (e.g. client/server, pipeline, blackboard)
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