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Bacterial Infections of Humans Epidemiology and Control Fourth Edition Edited by Philip S. Brachman, Emory University, and Elias Abrutyn, Drexel University. The new Fourth Edition of Bacterial Infections of Humans reflects a decade of important discoveries, technological progress, and valuable new therapies as well as emerging and reemerging infections, resistant strains of bacteria, and threats of bioterrorism. It offers accessible, up-to-date information across the range of disease entities. As in previous editions, introductory chapters review general concepts of infection and epidemiology, and the chapters devoted to specific infections follow a consistent and highly useful format: historical background, methodology (diagnosis and pathology), biology, descriptive epidemiology, mechanism and routes of transmission, pathogenesis, host responses, methods of prevention and control, and areas for future research. All material has been thoroughly updated, and two chapters on molecular epidemiology and health care-acquired bacterial infections, are entirely new. A sampling of the 40 diseases and clinical syndromes covered in the Fourth Edition: Anthrax Bacterial foodborne disease Chlamydia E. coli Legionellosis Meningitis Q fever Tuberculosis Bacterial Infections of Humans has been noted for ably complementing textbooks on the subject, and this most current edition remains a major reference for professionals in the field, including public health practitioners, microbiologists, immunologists, researchers studying pathogenic bacteria, clinicians working with infectious disease, and medical or nursing students.
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This book presents the state of art in the field of microbial zoonoses and sapronoses. It could be used as a textbook or manual in microbiology and medical zoology for students of human and veterinary medicine, including Ph.D. students, and for biomedicine scientists and medical practitioners and specialists as well. Surprisingly, severe zoonoses and sapronoses still appear that are either entirely new (e.g., SARS), newly recognized (Lyme borreliosis), resurging (West Nile fever in Europe), increasing in incidence (campylobacterosis), spatially expanding (West Nile fever in the Americas), with a changing range of hosts and/or vectors, with changing clinical manifestations or acquiring antibiotic resistance. The collective term for those diseases is (re)emerging infections, and most of them represent zoonoses and sapronoses (the rest are anthroponoses). The number of known zoonotic and sapronotic pathogens of humans is continually growing â over 800 today. In the introductory part, short characteristics are given of infectious and epidemic process, including the role of environmental factors, possibilities of their epidemiological surveillance, and control. Much emphasis is laid on ecological aspects of these diseases (haematophagous vectors and their life history; vertebrate hosts of zoonoses; habitats of the agents and their geographic distribution; natural focality of diseases). Particular zoonoses and sapronoses are then characterized in the following brief paragraphs: source of human infection; animal disease; transmission mode; human disease; epidemiology; diagnostics; therapy; geographic distribution.
Infectious diseases. Communicable diseases --- zoonoses --- besmettelijke ziekten
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Biological warfare has, unfortunately, in the post 9/11 world become a significant topic of discussion in both the medical and lay presses. In the wake of the biological "letter bombs" containing anthrax spores, the possibility of biologic and/or toxic attacks on civilians in any part of the world became no longer a possibility. It is now part of common discussion and consciousness. This book presents the history of the topics and clinically relevant discussions on those high risk (Category A) diseases beyond anthrax as well as a number of infections and toxins at the Category B level. Importantly, in addition, the text includes sections on Public Health Infrastructure, Public Health Law, Surveillance, Mental Health Management and Media Role all of which relate to epidemics of any sort, not just intentional biological events. Beyond Anthrax: The Weaponization of Infectious Diseases is a product that should serve as a reference point for clinicians, epidemiologists and public health personnel to understand in practical detail many of the aspects of weapons of biowarfare as well as the appropriate responses to them. It will be an invaluable information source for all those with an interest in biological warfare, including those who require a detailed, organized primer on the diseases thought to be those on the forefront of risk. Larry I. Lutwick, MD is Director of the Infectious Disease Unit at the Brooklyn Campus of the Veterans Affairs New York Harbor Health Care System in Brooklyn, New York and Professor of Medicine at the State University of New York, Downstate Medical Center. Suzanne M. Lutwick, MPH is Director of Grant Development for the Hackensack University Medical Center Foundation in Hackensack, New Jersey and adjunct faculty at State University of New York, Downstate Medical Center and at Seton Hall University, East Orange, New Jersey.
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The revised and up-to-date third edition of Drug Interactions in Infectious Diseases delivers a text that will enhance your clinical knowledge of the complex mechanisms, risks, and consequences of drug interactions associated with antimicrobials, infection, and inflammation. The third edition features five new chapters that cover material not addressed in previous editions. These new chapters describe interactions with a number of drug classes such as non-HIV antiviral, antimalarial, antiparasitic, antihelmintic, macrolide, azalide and ketolide agents. A novel chapter on probe cocktail studies has been included to highlight an important research tool for drug development. These chapters address material that cannot be retrieved easily in the medical literature. The highly acclaimed food-drug interactions as well as the study design and analysis chapters remain definitive references. The newly written drug-cytokine interaction highlights the need for our improved understanding of the complex interrelationship of acute infection, inflammation, and the risk of drug interactions. Informative tables on specific drug-drug interactions are provided throughout the chapters as a quick clinical resource. The Third Edition of Drug Interactions in Infectious Diseases is a distillation of relevant drug interactions associated with antimicrobials, infection, and inflammation. This concise review of the mechanisms and strategies to manage drug interactions should be valuable to all health care practitioners. Features · Definitive reference source of up-to-date information on antimicrobial drug interactions · Informative tables on the degree of interaction for specific antimicrobial agents · In-depth discussion of mechanisms and potential mechanistic pathways of interaction · New chapters on non-HIV antiviral, antimalarial, antiparasitic, and macrolide, azalide and ketolide agents · New chapter on probe-cocktail studies as a research tool to study drug-drug interactions · Inclusion of new antimicrobial agents and their associated drug interactions · First rate chapters on study design and analysis, and drug-food interactions · A fresh perspective on drug-cytokine interactions · Authoritative chapter on regulatory considerationsof drug interactions during drug development · Inclusion of new antimicrobial agents and their associated drug interactions
Pharmacology. Therapy --- Infectious diseases. Communicable diseases --- farmacologie --- besmettelijke ziekten
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The anthrax envelopes incident in the United States in 2001 created the impetus for a substantial increase in preparedness for bioterrorist threats among both public health and law enforcement professionals, worldwide. Ever increasing resources are now being allocated for dealing with a wide variety of potential threats, from the reintroduction of eradicated viruses such as smallpox to the possibility of genetically engineered novel pathogens. Despite the potentially devastating consequences of the various projected bioterror scenarios, it remains remarkably difficult to quantitatively assess the actual risk in each of these scenarios. Nevertheless, such risk assessment is crucial for determining the appropriate allocation of resources for research and preparedness. The public anxiety expected during a large-scale bioterrorism attack may even be more damaging than the direct effects of the bioterrorism agent, both in health-related and economic outcomes. Carefully tailored risk communication is a major tool for individuals, decision-makers or even entire communities to make educated decisions about their responses to well-being, and avoid social disruption. In this book, we have included articles from leading experts in the various disciplines associated with risk assessment and risk communication associated with bioterrorism. These papers are based on presentations at a NATO Advanced Research Workshop in Israel in June 2005, which addressed these issues. The resulting volume integrates the viewpoints of public health, law enforcement, risk analysis and media experts into a comprehensive, practical guide for approaching risk assessment and risk communication in a bioterrorism event.
Epidemiology --- Infectious diseases. Communicable diseases --- besmettelijke ziekten --- epidemiologie
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Dermatology is unusual as a medical specialty in that the traditional language of medicine often does not fit the needs of the specialty. The formal language of dermatology is so distinctive, it can take many months to learn, much like a foreign language. Similarly, dermatopathology has its own language that differs dramatically from the language of pathology. Dermatology Terminology uniquely describes and catalogs dermatologic diseases with the verbiage dermatologists use when speaking to each other. With many disorders, a description can be reduced to a word, phrase, or acronym, where such a keyword substitutes for a much fuller and lengthier formal presentation. This book is a compilation of these keywords, together with photos of the diseases they represent, coupled with short descriptions and literature references for each disease. The descriptions have been prepared over many years for dermatology residents and medical students and as such this book is a key learning resource for all students of dermatology.
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The goal of Schistosomiasis is to provide the reader with insights into the active research and programs currently related to schistosomiasis, and to use these insights as a way to project forward into the next 10-15 years of work on this disease, spanning the spectrum from research to public health interventions. A secondary goal of this volume is to initiate conversations among those working across the research-to-control spectrum on schistosomiasis about the future of their field, and by doing so lead to constructive efforts to identify and address the most critical questions and challenges related to schistosomiasis. The book covers four main areas: schistosome phylogenetics, gene expression, and the overall genome, including information on exciting new tools for addressing questions that have long been inaccessible to schistosomologists; the host-schistosome interaction at the larval to adult worm interface and addresses aspects important for vaccine development as well as how differential gene expression as detected by DNA microarrays may be utilized to develop tools for detection and control of infection or pathology; the development of the host immune response to eggs, granuloma formation and factors affecting the development and regulation of immunopathology; and the public health concerns associated with schistosomiasis, including morbidity control, host genetics, treatment and proposals for improved partnerships. The volume concludes with a chapter addressing the schisms that sometimes exist along the spectrum from basic research programs to the implementation of control schemes, and a proposal to make these differences benefit patients and researchers rather than succumb to base temptations to compete for resources to no one's benefit. Like many of the diseases featured in the World Class Parasites series, the prospects for dramatic advances in schistosomiasis coincide with a seemingly shrinking pool of both human and material resources. The most meaningful progress will occur as the laboratory better understands the needs in the field and the field better understands the capabilities of the laboratory.
Zoomorphology. Zooanatomy --- Infectious diseases. Communicable diseases --- morfologie --- besmettelijke ziekten --- zoölogie
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In the past, many tropical and parasitic infections were confined to tropical areas of the world located between the Tropic of Cancer and the Tropic of Capricorn. However, with the increase in air travel and tourism and the changing patterns of immigration, an increasing number of individuals are coming into contact with these infectious agents and transmission across the world has been enhanced. Tropical and Parasitic Infections in the Intensive Care Unit provides an international perspective on this topic and an overview of those infections that may cause critical illness. Charles Feldman, MB BCh., PhD, FRCP, FCP (SA) is a Professor of Pulmonology, Chief Physician and Head, Pulmonology Division of the University of the Witwatersrand Medical School in Johannesburg, South Africa. George Sarosi, MD is the Chief, Medical Service at Roudebush VA Medical Center and Professor of Medicine, Department of Internal Medicine at the Indiana University School of Medicine in Indianapolis, Indiana.
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The subspecialty of genitourinary or pelvic pain suffers from the lack of objective data and level-1 evidence. Genitourinary Pain and Inflammation: Diagnosis and Management of GU-ITIS is a compilation of skilled creativity based upon critical review of the literature, consensus reports, and professional experiences. It includes detailed chapters that address iatrogenic causes of GU inflammation, caused by catheters, prosthetics, radiation, or chemotherapy. Chapters in Genitourinary Pain and Inflammation: Diagnosis and Management of GU-ITIS also discuss pain syndromes specific to the pelvic floor and the genitourinary system from several perspectives. Experts in the urological and gastrointestinal fields provide the specifics for gaining the basic understanding of inflammation and pains caused by infectious etiologies.
Pathological dermatology --- Urology. Andrology --- Infectious diseases. Communicable diseases --- Surgery --- dermatologie --- urologie --- chirurgie --- pijn --- besmettelijke ziekten
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Sepsis is an important public health problem around the world. Severe sepsis carries significant morbidity, mortality and high costs. The incidence of sepsis is increasing because of the aging population, the growing number of immunocompromised hosts, the increasing use of invasive procedures, and, to a lesser extent, antibiotic resistance among pathogens. Despite recent advances in the pathogenesis, diagnosis, and therapeutic approaches the mortality rate associated with this condition remains high. Therefore, the goal of Sepsis: New Strategies is to review novel targets to be considered in patients with severe sepsis and to assess new developments for patients with sepsis originating in the respiratory tract.
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