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Reporter cells: - Yeast Based Sensors by Mifumi Shimomura-Shimizu and Isao Karube - Mammalian Cell-Based Sensor Systems by Pratik Banerjee, Briana Franz, and Arun K. Bhunia - Fluorescent and Bioluminescent Cell-Based Sensors: Strategies for Their Preservation by Amol Date, Patrizia Pasini, and Sylvia Daunert - Electrochemical Cell-Based Sensors by Eliora Z. Ron and Judith Rishpon - Microbial Cell Arrays by Tal Elad, Jin Hyung Lee, Man Bock Gu, and Shimshon Belkin Devices: - Surface Functionalization for Protein and Cell Patterning by Pascal Colpo , Ana Ruiz , Laura Ceriotti , and François Rossi - Fiber-Optic Based Cell Sensors by Evgeni Eltzov and Robert S. Marks - Electronic Interfacing with Living Cells by James T. Fleming - On-Chip Detection of Cellular Activity by R. Almog , R. Daniel , S. Vernick , A. Ron , H. Ben-Yoav, and Y. Shacham-Diamand
Chemistry. --- Biotechnology. --- Cell Biology. --- Biological Techniques. --- Analytical Chemistry. --- Analytical biochemistry. --- Cytology. --- Cytology --- Chimie --- Biochimie analytique --- Biotechnologie --- Cytologie --- Research_xMethodology. --- Biosensors --- Cells
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Earlier works on plant essential elements have revealed a series of complicated, counter-intuitive relationships among various chemical elements in different plant species, due to both unlike usage of certain elements in plants and to different carriers effecting resorption and transport. In an attempt to provide a more coherent theory behind plant mineral nutrition, this groundbreaking book adopts a very different approach from the existing literature, presenting an explanation of the essentiality of chemical elements in biological systems and the application of stoichiometric network analysis (SNA) to the biological system of elements. Starting with data from biochemical environmental analysis, and a discussion of the phenomena involved in metal ion partition and autocatalytic behaviour, conditions and criteria controlling the partition of metals into biomass are investigated. Several rules are derived and investigated in terms of their interaction both in comparisons among contemporary organisms and in terms of evolution. This allows the construction, for example of a map which directly traces the biological feature of essentiality to parameters of coordination chemistry. The book will have worldwide appeal for researchers interested in fields such as soil/plant interactions, bioinorganic chemistry, plant nutrition, phytomining, bioremediation, biogeochemistry, nutrient cycling, soil chemistry, and cellular physiology.
Life Sciences. --- Plant Biochemistry. --- Analytical Chemistry. --- Inorganic Chemistry. --- Molecular Ecology. --- Environmental Monitoring/Analysis. --- Life sciences. --- Analytical biochemistry. --- Chemistry, inorganic. --- Biochemistry. --- Molecular ecology. --- Sciences de la vie --- Biochimie analytique --- Biochimie --- Écologie moléculaire
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Organic Spectroscopy presents the derivation of structural information from UV, IR, Raman, 1H NMR, 13C NMR, Mass and ESR spectral data in such a way that stimulates interest of students and researchers alike. The application of spectroscopy for structure determination and analysis has seen phenomenal growth and is now an integral part of Organic Chemistry courses. This book provides: A logical, comprehensive, lucid and accurate presentation, thus making it easy to understand even through self-study; Theoretical aspects of spectral techniques necessary for the interpretation of spectra; Salient features of instrumentation involved in spectroscopic methods; Useful spectral data in the form of tables, charts and figures; Examples of spectra to familiarize the reader; Many varied problems to help build competence ad confidence; A separate chapter on ‘spectroscopic solutions of structural problems’ to emphasize the utility of spectroscopy. Organic Spectroscopy is an invaluable reference for the interpretation of various spectra. It can be used as a basic text for undergraduate and postgraduate students of spectroscopy as well as a practical resource by research chemists. The book will be of interest to chemists and analysts in academia and industry, especially those engaged in the synthesis and analysis of organic compounds including drugs, drug intermediates, agrochemicals, polymers and dyes. L.D.S. Yadav is currently Professor in the Department of Chemistry, University of Allahabad, India.
Chemistry. --- Organic Chemistry. --- Analytical Chemistry. --- Analytical biochemistry. --- Chemistry, Organic. --- Chimie --- Biochimie analytique --- Chimie organique --- Separation (Technology). --- Spectrum analysis. --- Chemistry --- Physical Sciences & Mathematics --- Biochemistry --- Spectrum analysis --- Chemistry, Organic --- Organic Chemistry --- Organic chemistry --- Analysis, Spectrum --- Spectra --- Spectrochemical analysis --- Spectrochemistry --- Spectroscopy --- Analytical chemistry. --- Organic chemistry. --- Analytic biochemistry --- Chemistry, Analytic --- Interferometry --- Optics --- Radiation --- Wave-motion, Theory of --- Absorption spectra --- Light --- Spectroscope --- Qualitative --- Spectrometry --- Analysis, Chemical --- Analytic chemistry --- Chemical analysis
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For the first time, distinguished scientists from key institutions worldwide provide a comprehensive approach to optical sensing techniques employing the phenomenon of guided wave propagation for chemical and biosensors. This includes both state-of the-art fundamentals and innovative applications of these techniques. The authors present a deep analysis of their particular subjects in a way to address the needs of novice researchers such as graduate students and post-doctoral scholars as well as of established researchers seeking new avenues. Researchers and practitioners who need a solid foundation or reference will find this work invaluable. This first of two volumes contains eight chapters covering planar waveguides for sensing, as well as sensing techniques based on plasmonic waveguides.
Chemistry. --- Analytical Chemistry. --- Industrial Chemistry/Chemical Engineering. --- Medical Biochemistry. --- Optics, Optoelectronics, Plasmonics and Optical Devices. --- Analytical biochemistry. --- Chemical engineering. --- Biochemistry. --- Chimie --- Biochimie analytique --- Génie chimique --- Biochimie --- Biosensors. --- Chemical detectors. --- Optical detectors. --- Optical wave guides. --- Optics, Lasers, Photonics, Optical Devices. --- Biodetectors --- Biological detectors --- Biological sensors --- Biomedical detectors --- Biomedical sensors --- Detectors --- Medical instruments and apparatus --- Physiological apparatus --- Chemical sensors --- Chemical apparatus --- Light-sensitive cells --- Light-sensitive detectors --- Light sensor photodevices --- Photodetectors --- Photodevices, Light sensor --- Photoelectric detectors --- Photosensors --- Optical transducers --- Optoelectronic devices --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Chemistry, Industrial --- Engineering, Chemical --- Industrial chemistry --- Engineering --- Chemistry, Technical --- Metallurgy --- Analytic biochemistry --- Biochemistry --- Chemistry, Analytic --- Composition --- Bioanalytic chemistry --- Bioanalytical chemistry --- Analytical chemistry --- Analytical chemistry. --- Medical biochemistry. --- Lasers. --- Photonics. --- Analysis, Chemical --- Analytic chemistry --- Chemical analysis --- New optics --- Optics --- Light amplification by stimulated emission of radiation --- Masers, Optical --- Optical masers --- Light amplifiers --- Light sources --- Nonlinear optics --- Optical parametric oscillators --- Medical biochemistry --- Pathobiochemistry --- Pathological biochemistry --- Pathology
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Nuclear Magnetic Resonance is a powerful tool, especially for the identification of 1 13 hitherto unknown organic compounds. H- and C-NMR spectroscopy is known and applied by virtually every synthetically working Organic Chemist. Con- quently, the factors governing the differences in chemical shift values, based on chemical environment, bonding, temperature, solvent, pH, etc. , are well understood, and specialty methods developed for almost every conceivable structural challenge. Proton and carbon NMR spectroscopy is part of most bachelors degree courses, with advanced methods integrated into masters degree and other graduate courses. In view of this universal knowledge about proton and carbon NMR spectr- copy within the chemical community, it is remarkable that heteronuclear NMR is still looked upon as something of a curiosity. Admittedly, most organic compounds contain only nitrogen, oxygen, and sulfur atoms, as well as the obligatory hydrogen and carbon atoms, elements that have an unfavourable isotope distribution when it comes to NMR spectroscopy. Each of these three elements has a dominant isotope: 14 16 32 16 32 N (99. 63% natural abundance), O (99. 76%), and S (95. 02%), with O, S, and 34 14 S (4. 21%) NMR silent. N has a nuclear moment I = 1 and a sizeable quadrupolar moment that makes the NMR signals usually very broad and dif cult to analyse.
Chemistry. --- Organic Chemistry. --- Organometallic Chemistry. --- Analytical Chemistry. --- Inorganic Chemistry. --- Polymer Sciences. --- Catalysis. --- Analytical biochemistry. --- Chemistry, inorganic. --- Chemistry, Organic. --- Polymers. --- Chimie --- Biochimie analytique --- Chimie organique --- Polymères --- Catalyse --- Electronic books. -- local. --- Nuclear magnetic resonance spectroscopy. --- Phosphorimetry. --- Biochemistry --- Analytical Chemistry --- Chemistry --- Physical Sciences & Mathematics --- Luminescence analysis --- Phosphorescence analysis --- Phosphorimetric analysis --- NMR spectroscopy --- Spectroscopy, NMR --- Spectroscopy, Nuclear magnetic resonance --- Analytical chemistry. --- Inorganic chemistry. --- Organic chemistry. --- Organometallic chemistry. --- Nuclear spectroscopy --- Knight shift --- Chemistry, Analytic --- Activation (Chemistry) --- Chemistry, Physical and theoretical --- Surface chemistry --- Polymere --- Polymeride --- Polymers and polymerization --- Macromolecules --- Inorganic chemistry --- Inorganic compounds --- Analytic biochemistry --- Organic chemistry --- Bioanalytic chemistry --- Bioanalytical chemistry --- Analytical chemistry --- Ressonància magnètica nuclear. --- Compostos orgànics --- Síntesi. --- Organometallic chemistry . --- Polymers . --- Analysis, Chemical --- Analytic chemistry --- Chemical analysis --- Chemistry, Organometallic --- Metallo-organic chemistry --- Chemistry, Organic --- Organometallic chemistry --- Polymers --- Catalysis
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Speci?c binding of a ligand to a receptor is a key step in a variety of biol- ical processes, such as immune reactions, enzyme cascades, or intracellular transport processes. The ligand-receptor terminology implies that the rec- tor molecule is signi?cantly larger than the ligand, and the term bioactive conformation usually characterizes the conformation of a ligand when it is bound to a receptor. In a more general sense, bioactive conformation applies toanymoleculeinabiologicallyrelevantboundstateregardlessofsizecons- erations. Mostofthecontributions tothisbookaddressligandsthat aremuch smaller than their receptors. X-ray crystallography and high resolution NMR spectroscopy are the two main experimental techniques used to study bioactive conformations. The- fore,the twovolumes ofthisbookcover approachesthat use either ofthetwo techniques, or a combination thereof. The combination of X-ray crystallog- phy and NMR spectroscopy is particularly useful when a crystal structure of areceptorprotein,butnotofthereceptorprotein-ligandcomplex,isavailable. Anumberofexperimentaltechniquestoanalyzethebioactiveconformationof aligandwithNMRarebasedontheobservationoftheresonancesignalsofthe free ligand that is in exchange with the bound ligand. Several chapters focus onsuchapproachesthat rangefromclassical transferredNOEexperiments, totransferred dipolar couplings,toSTD (saturation transfer difference) NMR techniques. Incaseswhere tightbinding inthesub-nanomolar rangeprevents the analysis of the bioactive conformation via free ligand signals, the ligand- proteincomplexhas tobeanalyzed withproteinNMR-based techniques orby crystallography.Sincethisareahasbeenthesubjectofmanyreviewsandmo- graphsitwill not be covered here in particular detail. As a unifying theme, all contributionstargetthequestionofhowmolecular recognitionofbiologically active molecules is achieved on the atomic scale. Depending on the research topic the results from these studies have a strong impact not only in basic research but also in several ?elds of application ranging frompharmaceutical applications tothe use of biomolecules as, for example, cryoprotectants.
Chemistry. --- Organic Chemistry. --- Biochemistry, general. --- Physical Chemistry. --- Medicinal Chemistry. --- Analytical Chemistry. --- Analytical biochemistry. --- Chemistry, Organic. --- Physical organic chemistry --- Biochemistry. --- Chimie --- Biochimie analytique --- Chimie organique --- Chimie organique physique --- Biochimie --- Conformational analysis --- Bioactive compounds --- Ligand binding (Biochemistry) --- Molecular Conformation --- Binding Sites --- Ligands --- Nuclear Magnetic Resonance, Biomolecular --- Protein Binding --- Analysis --- Chemistry --- Biochemistry --- Physical Sciences & Mathematics --- 577.354.3 --- Chemoreception --- 577.354.3 Chemoreception --- Conformational analysis. --- Analysis. --- Binding, Ligand (Biochemistry) --- Analysis, Conformational --- Biologically active compounds --- Compounds, Bioactive --- Compounds, Biologically active --- Compounds, Physiologically active --- Physiologically active compounds --- Analytical chemistry. --- Organic chemistry. --- Physical chemistry. --- Medicinal chemistry. --- Dye-ligand affinity chromatography --- Radioligand assay --- Molecular rotation --- Chemicals --- Chemistry, Physical organic. --- Analytic biochemistry --- Chemistry, Analytic --- Chemistry, Physical organic --- Chemistry, Organic --- Chemistry, Physical and theoretical --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Medical sciences --- Organic chemistry --- Composition --- Bioanalytic chemistry --- Bioanalytical chemistry --- Analytical chemistry --- Analysis, Chemical --- Analytic chemistry --- Chemical analysis --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Drugs --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Chemistry, Theoretical --- Physical chemistry --- Theoretical chemistry --- Bioactive compounds - Analysis
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see table of contents.
Chemistry. --- Polymer Sciences. --- Analytical Chemistry. --- Nanotechnology. --- Surfaces and Interfaces, Thin Films. --- Organic Chemistry. --- Analytical biochemistry. --- Chemistry, Organic. --- Polymers. --- Surfaces (Physics). --- Chimie --- Biochimie analytique --- Chimie organique --- Polymères --- Nanotechnologie --- Surfaces (Physique) --- Biomolecules --- Nanostructures --- Molecular biology --- Scanning tunneling microscopy --- Atomic force microscopy --- Analysis --- Research --- Molecular Biology --- Nanotechnology --- Microscopy, Scanning Probe --- Microscopy --- Genetics --- Biochemistry --- Natural Science Disciplines --- Miniaturization --- Manufactured Materials --- Technology --- Biological Science Disciplines --- Investigative Techniques --- Disciplines and Occupations --- Diagnostic Imaging --- Chemistry --- Biology --- Technology, Industry, and Agriculture --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Technology, Industry, Agriculture --- Diagnostic Techniques and Procedures --- Diagnosis --- Organic Chemistry --- Health & Biological Sciences --- Physical Sciences & Mathematics --- Atomic force microscopy. --- Scanning tunneling microscopy. --- Analysis. --- Research. --- STM (Microscopy) --- AFM (Microscopy) --- Analytical chemistry. --- Organic chemistry. --- Materials --- Thin films. --- Surfaces. --- Scanning probe microscopy --- Nanoscience --- Physics --- Molecular technology --- Nanoscale technology --- High technology --- Organic chemistry --- Surface chemistry --- Surfaces (Technology) --- Analytic biochemistry --- Chemistry, Analytic --- Polymere --- Polymeride --- Polymers and polymerization --- Macromolecules --- Bioanalytic chemistry --- Bioanalytical chemistry --- Analytical chemistry --- Polymers . --- Materials—Surfaces. --- Films, Thin --- Solid film --- Solid state electronics --- Solids --- Coatings --- Thick films --- Analysis, Chemical --- Analytic chemistry --- Chemical analysis --- Biomolecules - Analysis --- Nanostructures - Analysis --- Molecular biology - Research
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