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This book presents the functions and mechanisms of macropinocytosis, an actin-driven endocytic uptake process. Key points, including the evolutionary origins of macropinocytosis and major signaling pathways that regulate this uptake mechanism, are highlighted. A wide-array of functions of macropinocytosis are described, including cellular metabolism, cell death, cell migration and antigen presentation. Macropinocytosis has recently been recognized as a critical pathway in disease pathology and treatment. Therefore, a broad overview of macropinocytosis will benefit clinicians, as well as translational and basic research scientists. Moreover, as one of the main clathrin-independent endocytic routes, compiling all the critical information about macropinocytosis in one collection, this book will also be helpful to educators and their students.

Histology. Cytology --- General biophysics --- Biology --- Pathological biochemistry --- Human medicine --- celmembranen --- medische biochemie --- biofysica --- biologie --- biomedische wetenschappen --- cytologie --- histologie --- Cytology. --- Biophysics. --- Cell interaction. --- Biological transport. --- Cell membranes. --- Medicine --- Cell Biology. --- Mechanobiological Cell Signaling. --- Membrane Trafficking. --- Biomedical Research. --- Research. --- Citologia

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"This journal publishes papers ... covering all aspects of mechanisms, actions, and structural components of cellular signalling systems. The emphasis is on effector systems, such as protein kinases, lipid signalling pathways, cyclic nucleotide signalling processes, NO signalling and ion channels; the production, regulation, degradation and action of second messengers; the structure, regulation, degradation and action of receptors; guanine nucleotide regulatory proteins; bio-informatic studies related to cell signalling mechanisms; compartmentalisation/compartmentation of signalling systems; anchor/scaffold signalling proteins; the effect of cellular signalling events on the functioning, growth and differentiation of cells in normal and pathological states and also cellular oncogenes."

Genetics --- Cell interaction --- Signal Transduction --- Cellules --- Periodicals --- periodicals --- Interaction --- Périodiques --- Cell Communication. --- Transduction du signal cellulaire --- Cell interaction. --- Cell Biology. --- Signal Transduction. --- Receptor Mediated Signal Transduction --- Signal Transduction Pathways --- Signal Transduction Systems --- Receptor-Mediated Signal Transduction --- Signal Pathways --- Pathway, Signal --- Pathway, Signal Transduction --- Pathways, Signal --- Pathways, Signal Transduction --- Receptor-Mediated Signal Transductions --- Signal Pathway --- Signal Transduction Pathway --- Signal Transduction System --- Signal Transduction, Receptor-Mediated --- Signal Transductions --- Signal Transductions, Receptor-Mediated --- System, Signal Transduction --- Systems, Signal Transduction --- Transduction, Signal --- Transductions, Signal --- Cell Communication --- Receptor-CD3 Complex, Antigen, T-Cell --- Receptor Cross-Talk --- Feedback, Physiological --- Gasotransmitters --- Cellular Biology --- Cytology --- Biologies, Cell --- Biologies, Cellular --- Biology, Cell --- Biology, Cellular --- Cell Biologies --- Cellular Biologies --- Life Sciences --- Biology --- Cytology, Cell Biology --- Périodiques --- EJBIOMO ELSEVIER-E EPUB-ALPHA-C EPUB-PER-FT --- Cell Biology --- periodicals. --- Cell Signaling

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Lipides --- Transduction du signal cellulaire --- Prostaglandins --- Metabolisme --- Cell Communication. --- Lipid Metabolism. --- Signal Transduction. --- Receptor Mediated Signal Transduction --- Signal Transduction Pathways --- Signal Transduction Systems --- Receptor-Mediated Signal Transduction --- Signal Pathways --- Pathway, Signal --- Pathway, Signal Transduction --- Pathways, Signal --- Pathways, Signal Transduction --- Receptor-Mediated Signal Transductions --- Signal Pathway --- Signal Transduction Pathway --- Signal Transduction System --- Signal Transduction, Receptor-Mediated --- Signal Transductions --- Signal Transductions, Receptor-Mediated --- System, Signal Transduction --- Systems, Signal Transduction --- Transduction, Signal --- Transductions, Signal --- Cell Communication --- Receptor-CD3 Complex, Antigen, T-Cell --- Receptor Cross-Talk --- Feedback, Physiological --- Gasotransmitters --- Metabolism, Lipid --- Lipids --- Cell Interaction --- Cell-to-Cell Interaction --- Cell Communications --- Cell Interactions --- Cell to Cell Interaction --- Cell-to-Cell Interactions --- Communication, Cell --- Communications, Cell --- Interaction, Cell --- Interaction, Cell-to-Cell --- Interactions, Cell --- Interactions, Cell-to-Cell --- metabolism --- Periodicals --- Chemistry --- Health Sciences --- Life Sciences --- Biochemistry --- Physiology --- Cytology, Cell Biology --- Micro and Molecular Biology --- General biophysics --- General biochemistry --- biochemie --- Lipid Metabolism --- Signal Transduction --- Cell Signaling

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Pathological biochemistry --- Neuropathology --- Cerebrospinal Fluid --- Nervous System Diseases --- Cerebrospinal fluid --- Neurology --- Nervous system --- Alzheimer's disease --- Parkinson's disease --- Cerebrospinal fluid pressure --- Liquide céphalorachidien --- Neurologie --- Système nerveux --- Maladie d'Alzheimer --- Maladie de Parkinson --- Research --- Periodicals --- Diseases --- Recherche --- Périodiques --- Maladies --- Pression --- Neurology. --- Alzheimer's disease. --- Parkinson's disease. --- Cerebrospinal fluid proteins. --- Cerebrospinal fluid pressure. --- Cerebrospinal Fluid. --- Nervous System Diseases. --- Diseases. --- biochemie --- Nervous System Disorders --- Neurological Disorders --- Neurologic Disorders --- Disease, Nervous System --- Diseases, Nervous System --- Disorder, Nervous System --- Disorder, Neurologic --- Disorder, Neurological --- Disorders, Nervous System --- Disorders, Neurologic --- Disorders, Neurological --- Nervous System Disease --- Nervous System Disorder --- Neurologic Disorder --- Neurological Disorder --- Cerebro Spinal Fluid --- Cerebro Spinal Fluids --- Cerebrospinal Fluids --- Fluid, Cerebro Spinal --- Fluid, Cerebrospinal --- Fluids, Cerebro Spinal --- Fluids, Cerebrospinal --- Spinal Fluid, Cerebro --- Spinal Fluids, Cerebro --- CSF proteins --- Palsy, Shaking --- Paralysis agitans --- Parkinson disease --- Parkinsonism --- Shaking palsy --- Alzheimer disease --- Alzheimer's dementia --- Medical neurology --- Nerves --- Cerebrorachidian fluid --- CSF (Cerebrospinal fluid) --- Pressure --- CSF --- chemical signaling --- physical buffering --- chemical buffering --- neurodevelopment --- neurodevelopmental disorders --- Body fluids --- Proteins --- Brain --- Extrapyramidal disorders --- Basal ganglia --- Presenile dementia --- Senile dementia --- Medicine --- Neuropsychiatry --- Spinal cord --- Neurologic disorders --- Neurological disorders --- csf