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The future of food security will increasingly rely on more extensive exploration and effective exploitation of plant genetic resources. The remarkable progress in plant genomics, sequencing and bioinformatics offers unprecedented opportunities for mining germplasm collections, mapping and cloning loci of interest, identifying novel alleles and deploying them for breeding purposes.  Genomics of Plant Genetic Resources presents a state-of-the-art collection of highly interdisciplinary articles describing how genomics improves our capacity to characterize and harness natural and artificially induced variation in order to boost crop productivity and provide consumers with high-quality food. In the past decade, the appreciation of the value of biodiversity has grown rapidly, mainly due to the increased awareness of the pivotal role that plant genetic resources plays for securing the supply of plant-derived products. Meeting the challenges posed by climate change and the needs of the burgeoning population will require a quantum leap in crop productivity, which will only be possible through the integration of genomics-based approaches with extant breeding programs. Additionally, the new selection paradigm ushered in by genomics-assisted breeding will facilitate allele mining in orphan crops and underutilized species, previously less accessible via conventional approaches. The unifying picture that emerges from this book unequivocally shows the pivotal role played by genomics in order to mine germplasm collections, elucidate gene function, identify superior alleles and, ultimately, release improved cultivars. For each of these objectives, the book presents a number of compelling case studies and examples. This unique and timely book is an invaluable reference for educators, researchers, crop specialists, breeders and decision makers interested in managing, mining and harnessing the genetic richness of plant genetic resources. .

Biology --- bio-informatica --- genomics --- biologie --- klonen --- klimaatverandering

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Whether you're relatively new to git or you need a refresher, or if you just need a quick, handy reference for common tasks in git, Git Recipes is just the reference book you need. With recipes to cover any task you can think of, including working with GitHub and git on BitBucket, Git Recipes shows you how to work with large repositories, new repositories, forks, clones, conflicts, differences, and it even gives you practical scenarios you may find yourself dealing with while using git. If you work with Git at all, you need this hands-on, practical reference for all things Git.

Computer science --- Computer. Automation --- computers --- informatica --- klonen --- computerkunde

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This two-volume textbook provides a comprehensive overview on the broad field of Animal Biotechnology with a special focus on livestock reproduction and breeding. The reader will be introduced to a variety of state-of-the-art technologies and emerging genetic tools and their applications in animal production. Also, ethics and legal aspects of animal biotechnology will be discussed and new trends and developments in the field will be critically assessed. The two-volume work is a must-have for graduate students, advanced undergraduates and researchers in the field of veterinary medicine, genetics and animal biotechnology. This second volume is dedicated to genetic tools in animal biotechnology such as somatic cloning, transgenic technologies and the application of stem cells in livestock breeding. Also, ethics and legal aspects are discussed.

Molecular biology --- Animal embryology and growth --- Zoohistology. Zoocytology --- Animal husbandry --- stamcellen --- biotechnologie --- klonen --- moleculaire biologie

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This collection vigorously addresses the religious implications of extreme human enhancement technology. Topics covered include cutting edge themes, such as moral enhancement, common ground to both transhumanism and religion, the meaning of death, desire and transcendence, and virtue ethics. Radical enhancement programs, advocated by transhumanists, could arguably have a more profound impact than any other development in human history. Reflecting a range of opinion about the desirability of extreme enhancement, leading scholars in the field join with emerging scholars to foster enhanced conversation on these topics.

Philosophy --- Religious studies --- Sociology --- Genetics --- Engineering sciences. Technology --- transgenetische planten --- transgenetische dieren --- sociologie --- filosofie --- klonen --- ingenieurswetenschappen

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This book will contain the proceedings of the XV International Symposium on Retinal Degeneration (RD2012).  A majority of those who will speak and present posters at the meeting will contribute to this volume.  The blinding diseases of inherited retinal degenerations have no treatments, and age-related macular degeneration has no cures, despite the fact that it is an epidemic among the elderly, with 1 in 3-4 affected by the age of 70.  The RD Symposium will focus on the exciting new developments aimed at understanding these diseases and providing therapies for them.  Since most major scientists in the field of retinal degenerations attend the biennial RD Symposia, they are known by most as the “best” and “most important” meetings in the field.   The volume will present representative state-of-the-art research in almost all areas of retinal degenerations, ranging from cytopathologic, physiologic, diagnostic and clinical aspects; animal models; mechanisms of cell death; candidate genes, cloning, mapping and other aspects of molecular genetics; and developing potential therapeutic measures such as gene therapy and neuroprotective agents for potential pharmaceutical therapy.   While advances in these areas of retinal degenerations will be described, there will be many new topics that either were in their infancy or did not exist at the time of the last RD Symposium, RD2010.  These include the role of inflammation and immunity, as well as other basic mechanisms, in age-related macular degeneration, several new aspects of gene therapy, and revolutionary new imaging and functional testing that will have a huge impact on the diagnosis and following the course of retinal degenerations, as well as to provide new quantitative endpoints for clinical trials.   The retina is an approachable part of the central nervous system (CNS), and there is a major interest in neuroprotective and gene therapy for CNS diseases and neurodegenerations, in general.  It should be noted that with successful and exciting initial clinical trials in neuroprotective and gene therapy, including the restoration of sight in blind children, the retinal degeneration therapies are leading the way towards new therapeutic measures for neurodegenerations of the CNS.  Many of the successes recently reported in these areas of retinal degeneration sprang from collaborations established at previous RD Symposia, and many of those will be reported at the RD2010 meeting and included in the proposed volume.  We anticipate the excitement of those working in the field and those afflicted with retinal degenerations will be reflected in the volume.

Molecular biology --- Geriatrics --- Human genetics --- Neuropathology --- Ophthalmology --- neurologie --- medische genetica --- genetica --- geriatrie --- oftalmologie --- gentherapie --- gerontologie --- klonen --- moleculaire biologie