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"Part of the in-depth and practical Pattern Recognition series, Practical Surgical Soft Tissue Pathology, 2nd Edition, helps you arrive at an accurate diagnosis by using a proven pattern-based approach. Leading diagnosticians guide you through the most common patterns seen in soft tissue pathology, applying appropriate immunohistochemistry and molecular testing, avoiding pitfalls, and making the best diagnosis. High-quality illustrations capture key morphologic patterns for a full range of common and rare tumor types, and a "visual index" at the beginning of the book directs you to the exact location of in-depth diagnostic guidance"--Publisher's description.

Semiology. Diagnosis. Symptomatology --- Soft tissue tumors --- Neoplasms, Connective and Soft Tissue --- Neoplasm Grading. --- Diagnosis. --- pathology. --- diagnosis.

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This volume explores the mechanisms of resistance to targeted therapeutics. The focus is on the cancer cell signaling network, although other mechanisms of resistance including target mutation, and new areas of study such as cancer stem cells are included. Targeted Therapies: Mechanisms of Resistance highlights examples of changes in the signaling network in response to inhibition of a signaling event and underscores the importance in having a mechanistic understanding of the signaling network in cancer for developing effective targeted cancer therapies. Moreover, cutting edge tools to analyze the cell signaling network will be discussed. This includes the leading edge of techniques as well as computational biology and systems theory. This volume provides the reader with both an overview as well as a detailed perspective on the mechanisms of resistance to targeted therapeutics and will be of great value to the oncologist, the physician-scientist treating patients and the translational scientist working on any aspect of targeted therapeutics.

Molecular biology --- Oncology. Neoplasms --- oncologie --- moleculaire biologie --- Neoplasms --- Antineoplastic Agents --- Drug Resistance, Neoplasm. --- Molecular Targeted Therapy. --- Cancer --- Drug targeting. --- Médicaments --- drug therapy. --- therapeutic use. --- Treatment. --- Traitement --- Ciblage --- EPUB-LIV-FT LIVMEDEC SPRINGER-B