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Cell surface GRP78, a new paradigm in signal transduction biology
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ISBN: 9780128123522 0128123524 0128123516 9780128123515 Year: 2018 Publisher: London, England : Academic Press, an imprint of Elsevier,

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'Cell Surface GRP78, a New Paradigm in Signal Transduction Biology' presents a new paradigm that has emerged in the past decade with the discovery that various intracellular proteins may acquire new functions as cell surface receptors. Two very prominent examples are ATP synthase and GRP78. While the role of cell surface ATP synthase has been reviewed in various books, this book directs its attention to the story of cell surface GRP78.


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Lipid signaling and metabolism
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ISBN: 9780128194058 0128194057 0128194049 9780128194041 Year: 2020 Publisher: London, England : Academic Press,

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The value of BCG and TNF in autoimmunity
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ISBN: 9780128004616 0128004614 9780127999647 Year: 2014 Publisher: London, England : Academic Press,

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The Value of BCG and TNF in Autoimmunity provides an overview of current research and thinking related to tumor necrosis factor (TNF) induction and the use of the bacillus Calmette-Guérin (BCG) vaccine as potential treatment approaches to diverse forms of autoimmunity. BCG, commonly known as an anti-tuberculosis vaccine, is being explored in worldwide clinical trials as an approach to the treatment of certain forms of autoimmunity. The scope of research behind this therapeutic approach spans from the basic science of TNF signaling to research in diverse autoimmune disciplines, such


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PI3K and AKT Isoforms in Immunity : Mechanisms and Therapeutic Opportunities
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ISBN: 9783031065668 9783031065651 9783031065675 9783031065682 Year: 2022 Publisher: Cham : Springer International Publishing : Imprint: Springer,

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This book provides an essential overview of the role of phosphoinositide-3-phosphate kinase (PI3K) isoforms in modulating the function of immune system cells and their involvement in disease. PI3K is a family of kinases involved in basic cellular processes such as proliferation, migration and cell death. Recent work has highlighted the multiple roles of PI3K classes and subunits and their involvement in the immune response to the body’s own and foreign antigens and diseases such as cancer and autoimmunity. This book offers a detailed introduction to the biology of the three PI3K classes, followed by an extensive discussion of the diverse roles of AKT and PI3K isoforms in immune cells. Based on this knowledge, it subsequently explains in more detail how specific isoforms are connected to immune-mediated diseases. The book concludes by highlighting the latest advances in the production of isoform-specific inhibitors and their use in various human diseases. This book is intended as a reference guide for students and researchers interested in the multifaceted aspects of PI3K biology.

Disorders of visual processing
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ISBN: 9780444529275 0444529276 9780444512338 0444512330 Year: 2005 Publisher: [Place of publication not identified] Elsevier

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A volume in the Handbook of Clinical Neurophysiology series on the visual system. The ultimate reference source for clinical neurophysiologists on disorders of visual processing. Volume in a prestigious series published in association with the International Federation of clinical Neurophysiology. International contributor list drawn from around the world. Discusses anatomy and physiology, techniques used in clinical neurophysiology, disorders of peripheral visual processing and disorders of central visual processing.

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